Ferroptosis相关论文
Disulfiram, an aldehyde dehydrogenase inhibitor, works as a potent drug against sepsis and cancer vi
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Ferroptosis is a non-apoptotic regulated cell death caused by iron accumulation and subse-quent lipid peroxidation.Curre......
Owing to incurable castration-resistant prostate cancer(CRPC)ultimately developing after treating with androgen deprivat......
Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and ho
Acetaminophen(APAP)is a widely used analgesic and antipyretic drug,which is safe at ther-apeutic doses but can cause sev......
铁死亡（ferroptosis）是近年来新发现的，以铁依赖性的脂质活性氧（lipid reactive oxygen species，L-ROS）过度积累为特征的一种新的细胞程......
A novel anticancer property of Lycium barbarum polysaccharide in triggering ferroptosis of breast ca
Breast cancer is one of the most malignant tumors and is associated with high mortality rates among women. Lycium barbar......
目的:评价大鼠肺缺血再灌注时核因子E2相关因子2(Nrf2)与铁死亡的关系。方法:健康雄性SD大鼠54只，体重220~250 g，采用随机数字表法分......
脑出血是急性脑血管病死亡率最高的卒中亚型，占所有脑卒中的15%~20%。脑出血后继发性神经功能损伤的机制尚不明确，是否与脑出血后铁......
Tumor microenvironments self-activated nanoscale metal-organic frameworks for ferroptosis based canc
Ferroptosis,as a newly discovered cell death form,has become an attractive target for pre-cision cancer therapy.Several ......
Aberrant de novo lipid synthesis is involved in the progression and treatment resistance of many types of cancers,includ......
Ferroptosis,an iron-dependent form of regulated cell death driven by peroxidative damages of polyunsatu-rated-fatty-acid......
Oxidized low-density lipoprotein receptor 1 (OLR1) is upregulated in neurons and participates in hypertension-induced ne......
Versatile iron-vitamin K3 derivative-based nanoscale coordination polymer augments tumor ferroptotic
Ferroptosis is a newly form of regulated cell death,which has attracted great attention for tumor therapy.Herein,we prep......
ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and
Ferroptotic cell death is characterized by iron-dependent lipid peroxidation that is initiated by ferrous iron and H2O2 ......
Liproxstatin-1 is an effective inhibitor of oligodendrocyte ferroptosis induced by inhibition of glu
Our previous studies showed that ferroptosis plays an important role in the acute and subacute stages of spinal cord inj......
Objective Ferroptosisis identified as a new form of regulated cell death,which is morphologically,biochemically,and gene......
Objective Programmed cell death(PCD)plays important roles in normal biology,and its dysregulation impacts human disease.......
Activity-based protein profiling(ABPP)has emerged as a powerful functional chemoproteomic strategy which enables global ......
铁死亡是一种新型的细胞死亡方式，是指铁依赖下的活性氧过量蓄积，导致细胞发生致死性的脂质过氧化，最终引起细胞死亡。脂肪肝对缺血再......
Ferroptosis is a cell death modality triggered by excessive lipid peroxidation.Two recent studies (Zou et al.,2020;Cui e......
目的探讨索拉非尼诱导甲状腺癌TPC-1细胞铁死亡的作用。方法体外培养人甲状腺癌TPC-1细胞，对其处理并分为索拉非尼组和阴性对照组，利......
The cystine/glutamate antiporter SLC7A11 (also com-monly known as xCT) functions to import cystine for glutathione biosy......
BACKGROUND Colon adenocarcinoma(COAD)is one of the most common and fatal malignant tumors,which increases the difficulty......
糖尿病肾脏病是糖尿病主要并发症之一，也是终末期肾病的主要原因。铁在人体生命活动中十分重要，大量研究证据都表明，铁代谢与糖尿病肾......
Glutathione peroxidase 4 deficit-mediated fer⁃roptosis contributes to dopaminergic neuron degenerati
OBJECTIVE Intracellular aggre⁃gation ofα-synuclein(SNCA)is one of the core pathological features of neurodegenerative ......
N2L,a novel lipoic acid-niacin dimer,attenu⁃ates ferroptosis and decreases lipid peroxida⁃tion in HT
OBJECTIVE N2L is a novel lipoic acid-niacin dimer regulating lipid metabolism with multifunction,including antioxidant e......
Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivat
Ferroptosis is a type ofcell death accompanied by iron-dependent lipid peroxidation,thus stimu-lating ferroptosis may be......
MAFG-AS1/MAFG positive feedback loop contributes to cisplatin resistance in bladder urothelial carci
Though promoting ferroptosis can reduce cisplatin resistance in tumor cells,ferroptosis and cisplatin resistance in blad......
The essential trace element iron regulates a wide range of biological processes in virtually all living organisms.Becaus......
脓毒症是感染导致机体宿主反应失调引起的危及生命的器官功能障碍，在全球有较高的发病率与病死率。脓毒症的重要特征是炎症反应，剧烈......
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调节性坏死是新发现的新型细胞死亡途径，包括程序性坏死、细胞焦亡、铁死亡等。有研究报道，调节性坏死在缺血/再灌注、顺铂等药物、......
目的观察铁死亡在阿霉素（ADR）诱导小鼠局灶节段性肾小球硬化（FSGS）中的作用。方法雄性BALB/c小鼠按完全随机设计分为对照组和模型组，每......
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The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury. However, it is unclear wheth......
Ferroptosis is a type of programmed cell death dependent on iron. It is different from other forms of cell death such as......
The crosstalk between autophagy and ferroptosis: what can we learn to target drug resistance in canc
Autophagy is a conserved intracellular degradation system that plays a dual role in cell death; thus, therapies targetin......
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Ferroptosis is a novel form of regulated cell death distinguished from apoptosis,autophagy and other forms of cell death......
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Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammatio
Ferroptosis is a form of iron-dependent regulated cell death.Evidence of its existence and the effects of its inhibitors......
Clear cell renal cell carcinoma(ccRCC)is a common kidney malignancy characterized by a poor prognosis.Suppressor of vari......
Metformin is a widely prescribed hypoglycemic drug.Many studies have shown its anti-cancer properties.In the present stu......
Ferroptosis and autophagy,playing significant roles in tumor treatment,are two typical forms of the programmed cell deat......
研究设想:生命体的发育和稳固依赖于细胞存活、死亡和再生的平衡,而机体对于死亡细胞的清除是细胞更新换代的必然条件。常见的细胞......
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Sorafenib is the first-line medication for advanced hepatocellular carcinoma(HCC),but it can only extend limited surviva......
Sorafenib is the first-line treatment of advanced hepatocellular carcinoma(HCC).However,there is a lack of validated bio......
Lysosome is a ubiquitous acidic organelle fundamental for the turnover of unwanted cellular molecules,particles,and orga......
Ferroptosis is a newly characterized iron-dependent form of nonapoptotic regulated cell death triggered by lipid reactiv......
,Beclin1-mediated ferroptosis activation is associated with isoflurane-induced toxicity in SH-SY5Y n
The widely used inhalation anesthetic,isoflurane,potentially induces neuronal injury in clinical practice.Previous studi......
