Disease-mediated alterations to drug disposition constitute a significant source of adverse drug reactions.Cisplatin(CDD......

目的:探讨不同化疗药物联合DNA甲基化酶抑制剂5-氮杂-2\'-脱氧胞苷（5-Aza-dC）对肺腺癌细胞A549细胞凋亡的影响。方法:采用前瞻性随......

目的:评价含十字形结构域蛋白3(JMJD3)在顺铂致急性肾损伤小鼠肾纤维化中的作用。方法:健康C57BL/6雄性小鼠48只，8~10周龄，体重20~30......

目的:探讨GNG4与卵巢癌顺铂耐药A2780/DDP细胞DNA损伤修复及化疗敏感性的关系。方法:将A2780/DDP细胞分为500 ng/ml顺铂作用组（cDDP......

Mitochondria are essential organelles that provide energy for mammalian cells and participate in multiple functions,such......

Cisplatin is a clinically advanced and highly effective anticancer drug used in the treatment of a wide variety of malig......

目的:探讨热疗对人喉癌Hep-2顺铂耐药（Hep-2/CDDP）细胞株生物学行为的影响和可能机制。方法:采用高浓度冲击联合浓度递增法诱导建立H......

目的:探讨血清miRNA-126（miR-126）、miRNA-449a（miR-449a）的表达水平对培美曲塞联合顺铂治疗非小细胞肺癌（NSCLC）的效果和预后的评估作用......

目的:探讨顺铂序贯重组人血管内皮抑制素胸腔灌注治疗恶性胸腔积液的疗效。方法:选取2018年1月至2021年2月茂名市人民医院收治的80......

目的:探讨正电子凋亡显像剂n 18F-2-（5-氟-戊基）-2-甲基丙二酸（n 18F-ML-10）检测顺铂诱导的肺腺癌A549细胞凋亡情况的可行性......

Objective:To examinie the synergistic effects of Banxia Xiexin Decoction（半夏泻心汤,Known as Banhasasim-tang in Korean) e......

Cisplatin and other platinum-based drugs are used frequently for treatment of lung cancer.However,their clinical perform......

Aim: To evaluate the protective effects of ginger (Gin) and roselle (Ros) against testicular damage and oxidative stress......

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DNA-damaging agents have been reported to be associated with cardiovascular complications;however, the underlying mechan......

Uncontrolled growth and metastasis are two fatal hallmarks of malignant tumors,which represent the dominant challenges f......

Nanoparticles mainly remain in the perivascular regions of solid tumors (Dmean...

Camels,belonging to the family Camelidae,are found throughout the world.This study deals mainly with the one-humped (dro......

As one of the most fatal diseases around the world,cancer is usually treated with chemotherapy,radiation therapy,and sur......

The uterine cervix carcinoma is one of the malignant diseases where platinum-based drugs such cisplatin are included in ......

Cisplatin is one of the most important and frequently used cytostatic drugs for the treatment of cancer.The cytostatic e......

Doxorubicin hydrochloride (DOX·HCl),an anthracycline antibiotic,is used in the first line treatment for a wide range of......

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Cisplatin is one of the most widely used anticancer agents[1].However,its therapeutic concentration is usually associate......

Objective: To Study on Increasing Efficacy and Reducing Toxic Substance of Angelica Sinensis and Sophorae Flavescentis a......

Osteosarcoma(OS)is the most common cancers in bone.Chemotherapy is commonly used for the clinical treatment of OS....

Objective Nasopharyngeal cancer,occurring at the top and side walls of the nasopharyngeal cavity,is one of the most comm......

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Background: Oldenlandia diffusa (OD) is a well-known traditional Chinese medicine, which is used to prevent and treat ma......

Objective:The present paper describes a comparative characterization of cytotoxic effects of doxycycline and cisplatin o......

This study was to explore a mechanism by which hydrogen sulfide(H2S)may protect human bone marrow-derived mesenchymal st......

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Objective: Toprepareadrugcarrier(Fe3O4/PAA-PEI)anddrug-loadedmagneticnanoparticles(Fe3O4/PAA-PEI-DDP)for effectivekillin......

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目的 Paclitaxel liposome plus cisplatin is an effective preoperative chemotherapyregimen which widely used for locally a......

目的 Our study was designed to investigate the usefulness of 99mTc-3PRGD2 SPECT forno-invasively monitoring the response......

Objective Platinum drugs and paclitaxel are widely used in the treatment of advanced bladder cancer.However,the efficacy......

Objective Artesunate(ART)has been used extensively as anti-malarial drugs worldwide.Besids,it has also been reported to ......

Objective Cisplatin is the major chemotherapeutic drug in gastric cancer,especially for advanced gastric cancer.The tumo......

目的 Cisplatin is widely used in the treatment of several solid malignant tumors,including gastric cancer(GC).However,ge......

Objective: Ovarian cancer is one of the most lethal of women cancers and lack potent therapeutic options.There have many......

Volasertib (BI 6727),a highly selective and potent inhibitor of PLKI,has shown broad antitumor activities in the preclin......

Aim Ethnopharmacological relevance: Ribes diacanthum Pall.(Saxifragaceae) , a Mongolian folk medicinal plant, was used t......

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Chrysin(5,7-dihydroxyflavone) exists widely in plants, honey and propolis.The anticancer property of chrysin has been de......

Aim: Failure to engage apoptosis appears to be a leading mechanism of resistance to traditional platinum drugs in patien......

ObjectiveThe present paper describes a comparative characterization of cytotoxic effects of doxycycline and cisplatin on......

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