sorafenib相关论文
目的:明确低浓度索拉非尼（sorafenib）与RSL3联合用药增强肝癌细胞的杀伤作用。探究sorafenib、RSL3二者联合用药与gasdermin（GSDME）介......
目的 Hespintor是本课题组在2005年利用抑制性消减杂交（suppression subtractive hybridization,SSH）技术,从肝母细胞瘤细胞系Hep G2......
背景及目的肝癌（HCC）作为导致癌症病人死亡的重要原因,对我国人民身体健康造成巨大威胁。正常情况下,肿瘤的治疗方式包括手术切除、......
肝细胞癌（hepatocellular carcinoma,HCC）是一种具有高复发率和高死亡率的恶性肿瘤疾病。乙型肝炎病毒（Hepatitis B virus,HBV）编码的X......
Efficacy and Safety of Second-line Treatments in Patients with Advanced Hepatocellular Carcinoma aft
Background and Aims: In the last decade, several sec-ond-line therapies followed by sorafenib in patients with ad-vanced......
The multikinase inhibitor sorafenib induces caspase-dependent apoptosis in PC-3 prostate cancer cell
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Nanodiamond loading insoluble sorafenib enhances oral delivery and inhibited tumor metastasis of gas
Tumor metastasis is one of the greatest hurdles for cancer treatment, which accounts for 90% of cancer-associated mortal......
iRGD decorated lipid-polymer hybrid nanoparticles for targeted co-delivery of doxorubicin and sorafe
The combination of doxorubicin(DOX)with sorafenib(SOR)has been proved to be an effective strategy to enhance anti-hepato......
Computed tomographytextureanalysisofintermediate-advanced hepatocellularcarcinoma:implication
Background & Aims:Transcatheterarterial chemoembolization(TACE)andsorafenibcombinationtreatmentforunselected hepatocellu......
Sorafenib combined with TACE treatment:the effect of inhibiting portal vein invasion for hepatocellu
Purpose: This study aims to investigate the effect of combining sorafenib with Transarterial Chemoembolization (TACE) fo......
Objective Combination treatment through simultaneous delivery of anticancer drugs and gene with nano-formulation has bee......
Apatinib for patients with sorafenib-refractory advanced hepatocellular carcinoma:Results of a pilot
Objective Background: More than half of patients with advanced hepatocellular carcinoma(HCC)do not respond to primary tr......
Efficacy and safety for sorafenib in Chinese patients with metastasis renal cell cancer:a single-cen
Objective RCC is considered to be one of the most treatment-resistant cancers and is the tenth cancer-related cause of d......
Sorafenib with and without transarterial chemoembolization for advanced hepatocellular carcinoma wit
Background: The survival benefit of combining sorafenib and transarterial chemoembolization (TACE) therapy compared with......
Evaluation of Anti-angiogenic and Anti-proliferative Effects of orafenib by Sequential Histology and
Purpose To investigate the effectiveness of intravoxel incoherent motion (IVIM) in the assessment of the therapeutic eff......
Objective Liver cancer is the second leading cause of cancer related death globally.Hepatocellular carcinoma(HCC)account......
Platelet-albumin-bilirubin index:a valuable assessment method for prognostic prediction in HCC patie
Objective Background and aim: As repetitive transcatheter arterial chemoembolization(TACE)or combined therapy of TACE wi......
Objective An open-label,randomized,multicentre phase 3 trial(REFLECT)compared the efficacy and safety of lenvatinib vers......
FOXM1-mediated Linc-ROR Regulates the Proliferation and Sensitivity to Sorafenib in Hepatocellular C
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Prognostic analysis of Sorafenib treatment in patients with lung metastasis from advanced hepatocell
Purpose To evaluate the clinical efficacy of sorafenib treatment in patients with lung metastasis from advanced hepatoce......
Preliminary results of Main Portal Vein Tumor Thrombus treated by Endovascular Brachytherapy combine
Aim:To evaluate the safety and efficacy of endovascular brachytherapy(EVBT)with Iodine-125(125I)seeds strand implantatio......
目的：观察吡喹酮杀虫基础上Sorafenib对日本血吸虫病肝纤维化的治疗作用。方法：将SPF级雌性BALB/C小鼠随机分为6组：正常对照组、感染......
Sorafenib with or without transarterial chemoembolization for advanced hepatocellular carcinoma with
Background:The survival benefit of combining sorafenib and transarterial chemoembolization(TACE)therapy compared with so......
Sorafenib continuation or discontinuation in patients with unresectable hepatocellular carcinoma aft
Aims:To assess the efficacy of continued administration of sorafenib for patients with unresectable hepatocellular carci......
Reconsidering sorafenib-related trial design:amulticenter cohort study on transarterial chemoemboliz
Background & Aims:We conducted this multicenter retrospective study to evaluate the efficacy of sorafenib combined with ......
Transarterial chemoembolization in combination with sorafenib in the treatment of intermediate-advan
Objective To identify the survival benefits and safety of transarterial chernoembolization (TACE) combined with sorafeni......
Effectiveness and the strategy to treat the side effects of sorafenib administration after transarte
Objective:to study the clinical response and side effects of sorafenib administration after transarterial chemoembolizat......
Sraem:a Prognostic score to predict overall survival following combinat ion therapy with TACE and so
Aims:The purpose of our study was to establish a prognostic score to predict overall survival following combination ther......
目的 观察吡喹酮杀虫基础上Sorafenib对日本血吸虫病肝纤维化的治疗作用。方法 将健康雌性BALB/C小鼠随机分为6组：正常对照组、感染......
Hepatic arterial administration of sorafenib and iodized oil effectively attenuates tumor growth and
Aim: To investigate the therapeutic effect of the hepatic arterial administration of sorafenib in rabbit VX-2 hepatocell......
Activation of AKT-AP1-FOXM1 signaling pathway confers sorafenib resistance to hepatocellular carcino
Sorafenib is the first-line drug for advanced hepatocellular carcinoma(HCC),but the clinical response to sorafenib is se......
Purpose: To observe the efficacy and safety of sorafenib for advanced hepatocellular carcinoma with TACE refractoriness....
Efficacy and safety for sorafenib in Chinese patients with metastasis renal cell cancer:a single-cen
Purpose To evaluated the efficacy and safety of sorafenib for Chinese patients with mRCC.Methods We analyzed the clinica......
Sorafenib,a small-molecule drug for renal cell carcinoma (RCC),targets multiple kinases including inhibiting the serine-......
Preventive Effect of Celecoxib on Sorafenib-related Hand-Foot Syndrome in Hepatocellular Carcinoma P
目的 Skin toxicity,especially hand-foot syndrome(HFS),is the most common sorafenibinduced adverse events in hepatocellul......
The efficacy and safety of sorafenib in Chinese patients with metastatic renal cell carcinoma and pr
Objective: Sorafenib has been recommended as first-or second-line treatment for metastatic renal cell carcinoma(mRCC)by ......
iRGD decorated lipid-polymer hybrid nanoparticles for targeted co-delivery of doxorubicin and sorafe
The combination of doxorubicin (DOX) with sorafenib (SOR) has been proved to be an effective strategy to enhance anti-he......
An 81-year-old male with unresectable hepatocellular carcinoma underwent transarterial chemoembolization (TACE) combined......
目的探讨索拉非尼诱导甲状腺癌TPC-1细胞铁死亡的作用。方法体外培养人甲状腺癌TPC-1细胞，对其处理并分为索拉非尼组和阴性对照组，利......
Experimental Research on the Inhibitory Effect of IFN-Lambda 3 Combined with Sorafenib on the Growth
Objective:To investigate the effect of sorafenib combined with interferon-lambda 3 on the growth of liver cancer transpl......
目的 研究Sorafenib通过诱导铁死亡来抑制DU145前列腺癌细胞增殖的机制。方法 分别用Sorafenib、铁死亡诱导剂RSL3和FIN56以及上述......
Recent advances of sorafenib nanoformulations for cancer therapy:Smart nanosystem and combination th
Sorafenib,a molecular targeted multi-kinase inhibitor,has received considerable interests in recent years due to its sig......
