metformin相关论文
目的:糖尿病患者治疗中应用阿卡波糖,并分析其有效性及安全性.方法:选取2019年10月-2021年10月,在我院治疗的92例糖尿病患者.采取......
Based on the host-guest molecular recognition capability of cucurbit[6]uril (CB[6]) modified on the gold surface,sensiti......
目的:分析初诊2型糖尿病应用达格列净联合二甲双胍治疗效果情况?方法:资料选取2020年6月-2021年6月本院诊治的84例初诊2型糖尿病患......
目的:对二甲双胍+阿卡波糖联合治疗2型糖尿病的临床效果及对患者血糖水平的改善作用进行评价?方法:课题研究对象为2019年12月~2020......
目的:观察瑞格列奈与二甲双胍治疗2型糖尿病的效果和患者不良反应?方法:选取我院2型糖尿病患者78例(2019年7月至2020年9月)，随机分......
目的 分析2型糖尿病疾病特点，探讨甘舒霖30R联合二甲双胍治疗2型糖尿病的效果，为糖尿病治疗工作提供参考。方法 选择我院2018年3月至......
The expanded lifespan of people, while a positive advance, has also amplified the prevalence of age-related disorders, w......
Short-term combined treatment with exenatide and metformin for overweight/obese women with polycysti
Background::Obesity and insulin resistance (IR) are common features of polycystic ovary syndrome (PCOS). Metformin (MET)......
Objective: To evaluate the preventive effect of salvianolate (Sal B) onglucose metabolism disorders of dimethylnitrosami......
Chronic Intracerebroventricular Infusion of Metformin Inhibits Salt-Sensitive Hypertension via Atten
Metformin (MET),an antidiabetic agent,also has antioxidative effects in metabolic-related hypertension.This study was de......
Heart healthy equals prostate healthy and statins,aspirin, and/or metformin (S.A.M.) are the ideal r
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Hyaluronic Acid-Drug Conjugate of Docetaxel and Metformin to Target Cancer Cells and Cancer Stem Cel
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Complementary synergy of metformin in combination with HDACi to overcome EGFR-TKI resistance via BIM
目的 Drug resistance to epidermal growth factor receptor tyrosine kinase inhibitor(EGFR-TKIs)is the main obstacle for cl......
MetforminenhancescytotoxicityinducedbygefitinibinH1975cellsviareversingEMTandsuppressin
目的 AlthoughtheEGFRtyrosinekinaseinhibitors(EGFR-TKI)haveshownstrikingeffectsagainstEGFRmutantlungcancer,butpatientswit......
目的 Toinvestigatetheeffectsofthecombinationofmetforminandicotinibontheproliferation,apoptosisandmigration,invasioncapab......
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Effects of metformin on the expression of GLP-1R in the enteric nervous system of type 2 diabetic ra
Aim: To study the effects of metformin on the expression of Glucagon-like peptide1receptor (GLP-1R) in the enteric nervo......
Background: Oxidative stress is a causal factor and key promoter of urolithiasis associated with renal tubular epitheliu......
Bone remodeling involves synthesis of organic matrix by osteoblasts and bone resorption by osteoclasts.Recently, anti-di......
studies have reported mefformin, an insulin-sensitizer drug commonly used for type 2 diabetes, could enhance differentia......
Aim: 5 Adenosine monophosphate-activated protein kinase (AMPK) was reported to form transcriptional complex with peroxis......
Diane-35 combinated with metformin attenuates carbohydrate and lipid metabolic index in polycystic o
AIM:To evaluate the effects of combined metformin and Diane-35 administration in polycystic ovary syndrome(PCOS)patients......
Metformin use is associated with better survival of breast cancer patients with diabetes-a Meta-anal
Objective: Diabetic patients with breast cancer receiving metformin and neoadjuvant chemotherapy have a higher pathologi......
Metformin attenuates angiotensin Ⅱ induced cardiac fibrosis and transforming growth factor-β1 produc
Aim In diabetic patients, mefformin appears to provide cardiovascular protection that cannot be attributed only to its a......
Combination of metformin and curcumin exhibits synergistic inhibitory effects on tumor growth and me
OBJECTIVE Hepatocellular carcinoma (HCC) is the most common cause of cancer-related mortality, with high incidence rates......
Development and validation of an improved LC-MS/MS method for simultaneous quantitation of metformin
Objective To support the pharmacokinetic study of metformin (MET) hydroehloride/pioglitazone (PIO) hydroehloride tablet,......
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Long-term metformin treatment reduces the risk of stroke.However,the effective administration pattern and indications of......
Biocompatible polymeric nanocomplexes as an intracellular stimuli-sensitive prodrug for type-2 diabe
Combination therapy is usually considered as a promising strategy owing to its advantages such as reduced doses, minimiz......
Metformin prevents cancer metastasis by inhibiting M2-like polarization of tumor associated macropha
Aim Accumulated evidence suggests that M2like polarized tumor associated macrophages (TAMs)plays an important role in ca......
Metformin attenuates Cd-induced neuronal apoptosis via blocking ROS-dependent AMPK/PP5-JNK signaling
Cadmium(Cd),a toxic environmental contaminant,induces reactive oxygen species(ROS)-dependent neuronal apoptosis and cons......
Progress in the application and mechanism of metformin in treating non-small cell lung cancer (Revie
Currently,the incidence and mortality from lung cancer manifests an increasing trend.Non-small cell lung cancer (NSCLC) ......
Objective: Metformin,an anti-diabetic drug commonly used for type 2 diabetes therapy,is associated with anti-angiogenic ......
Aim: The anti-diabetic drug metformin exerts chemopreventive and antineoplastic effects in many types of malignancies.We......
Metformin enhances the long-term persistence and antitumor ability of CD8+T lymphocytes through AMPK
Objective T cells are phenotypically categorized into naive precursors(Tn)cells,central memory(Tcm)cells,effector memory......
Metformin promotes functional recovery following experimental stroke via inducing alternative polari
OBJECTIVE Acute AMPK activation exacerbates ischemic brain damage experimentally.Paradoxically, the clinical use of an A......
Anti-diabetic drug metformin has been shown to enhance osteoblasts differentiation and inhibit osteoclast differentiatio......
Elevated expression of phospho-acetyl-CoA carboxylase protein is an independent prognostic factor fo
Background As a rate-limiting enzyme of fatty acid synthesis, acetyl-CoA carhoxylases (ACC) up-regulation has been recog......
Short-term combined treatment with exenatide and metformin for overweight/obese women with polycysti
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目的 分析沙格列汀联合二甲双胍治疗2型糖尿病（T2DM）代谢性肥胖患者对其体脂成分的改善效果。方法 选择我院2018年1月至2019年9月收......
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