Hippo相关论文
目的 研究槐耳清膏对三阴性乳腺癌细胞增殖和迁移的作用及其可能的机制。方法 采用CCK-8法及小鼠移植瘤模型检测槐耳清膏对乳腺癌......
第一部分 聚乙烯亚胺-葡聚糖四氧化三铁磁性纳米粒子合成与表征目的:合成带正电荷的聚乙烯亚胺-葡聚糖四氧化三铁磁性纳米粒子（poly......
研究目的:观察长期的游泳运动对幼年自发性高血压大鼠肠系膜动脉平滑肌细胞表型转换及血管舒缩功能的影响,并进一步探讨Hippo-YAP......
FHL2（Four and a half LIM domains 2）作为转录因子共结合子参与调控基因表达、信号通路转导以及细胞生长等多种生物学过程。前期研......
背景:食管癌是我国高发、地域性明显的恶性肿瘤,全球每年新发病例中约50%以上发生在中国,而河南地区是全球食管癌发生率和死亡率最......
前期研究表明,蛹虫草活性成分虫草素能有效抑制乳腺癌移植瘤的生长和转移,但其作用机制未清楚.本研究取三阴性乳腺癌移植瘤样品,通......
目的 探讨青蒿琥酯诱导白血病细胞凋亡的分子机制。方法 蛋白质组学(iTRAQ)分析青蒿琥酯处理M5急性髓系白血病细胞THP-1后的差异表......
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PPP2R2A-containing PP2A complex negatively regulates HIPPO pathway by dephosphorylating AMOTL2 at Se
The HIPPO signaling pathway is a conserved tumor suppressor signaling pathway.Protein phosphatase 2A(PP2A)complex includ......
Nitidine chloride(NC)exhibits tumor suppressive function in a variety of human cancer types.However,the molecular mechan......
The G protein-coupled estrogen receptor (GPER) is a physiological estrogen receptor mediating both the genomic and non-g......
本研究旨在考察蛋白质磷酸酶4催化亚基（protein phosphatase 4 catalytic subunit, PP4C）对肺癌肿瘤生长和转移的调控作用。通过逆转......
期刊
Objective Programmed cell death(PCD)plays important roles in normal biology,and its dysregulation impacts human disease.......
OBJECTIVE To investigate the effect of scutellarin on the apoptosis of human colorectal cancer cells via the Hippo signa......
目的 研究和厚朴酚(honokiol,HNK)对结肠癌SW620细胞的增殖抑制作用及其机制.方法 采用结晶紫染色法、流式细胞术和Western blot等......
YAP/TAZ在头颈肿瘤中普遍异常激活,且对肿瘤生长调控意义重大,故直接靶向YAP/TAZ在头颈部肿瘤治疗中具有极高的潜能。但是随着研究......
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沙棘为胡颓子科,沙棘属(Hippophae L.)植物的总称。在不同的地区,人们冠以种种地方名称,诸如沙棘、醋柳、黄酸刺、酸刺、黑刺、海......
《温图克》(Wintuk)是加拿大太阳马戏团在2007年冬季上演的儿童剧目,由太阳马戏团、MSG娱乐公司(MSG Entertainment)以及BASE娱乐......
来自于美国得克萨斯大学西南医学中心的研究人员在果蝇中发现一个可同时限制细胞增殖并促进细胞死亡的肿瘤抑制基因;该基因有可能......
目的研究低温对大鼠学习记忆能力及海马区细胞线粒体融合基因与分裂基因mRNA表达的影响。方法选取健康Wister大鼠32只，按低温处理时......
Intercellular adhesion molecule-1 expression in the hippocampal CA1 region of hyperlipidemic rats wi
Chronic cerebral ischemia is a pathological process in many cerebrovascular diseases and it is induced by long-term hype......
Effect and mechanism of Polygonatum sibiricum polysaccharide on osteogenic differentiation of bone m
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
背景:食管癌是全球发病率排名前10位、致死率不断攀升的恶性肿瘤,呈明显地域分布差异,是河南等地区发病率和致死率最高的恶性肿瘤......
Hippo信号通路参与多种生物学过程,如胚胎发育、器官大小调控、成体干细胞维持、天然免疫调节、肿瘤发生发展。该通路已经成为生命......
目的:单核巨噬细胞系统是机体重要的免疫防御屏障,由单核细胞、各组织中的巨噬细胞以及原单核和幼单核细胞组成,这些细胞均属单核......
布鲁克斯皮格勒综合征(Brooke-Spiegler syndrome,BSS)是一种罕见疾病,是病变发生在皮肤及皮肤附属器上的综合征,大多数病人在成年......
目的:肺癌的发病率和死亡率位居世界首位。2018年全球有约210万例新增肺癌病例和176万例肺癌死亡病例,肺癌死亡病例大约占癌症死亡......
在个体的生长发育过程当中,体内是如何调控那些组织器官的形态大小的是一个至关重要的问题。在过去的几十年里,已经找到了一系列调......
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一、故事内容A football team needs a goalkeeper.Many animals want to have a try.Look,Deer is coming.He is 180 cm tall.But......
Hippos(1)live in Africa.Sometimes they walk a long way to find water.Hippos love to play in the water in the day.They li......
Correlation between level of serum prolactin and epileptic discharges of electroencephalogram from 2
BACKGROUND: Researchers discovered that serum prolactin could rise following an epileptic seizure. The prolactin level m......
乙型肝炎是外科医师的一种职业病,有值得注意的发病率及一定的死亡率。这是外科医师为腹痛病人作鉴别诊断时必须考虑到的一种疾病......
Teaching goals 1.Learn:fur,Tibetan,antelope,endanger,jungle,wolf,hippo,kangaroo,giraffe 2.Let the students talk about th......
Studies have confirmed that iron induces epilepsy onset,and iron ion-induced epilepsy in animal models closely resembles......
Phosphodiseterases(PDEs),a superfamily of 11 enzymes(PDE1-11) that hydrolyze cyclic nucleotides(cAMP and cGMP),mediate a......
为探讨去整合素-金属蛋白酶17(disintegrin and metalloproteinase 17,ADAM17)对人胶质瘤细胞增殖和迁移的影响及其调控机制,该研......
当Hippo信号通路以及Wnt信号通路出现异常,患者发生结直肠癌的概率增大,转录共激活因子(TAZ)和β-catenin作为Hippo信号通路和Wnt......
More evidence has underscored the importance of Hippo signaling pathway in gastrointestinal tissue homeostasis, whereas ......
The Effects of Flavonoids from Scutellaria Stem and Leaf on the Expression of NMDAR and VEGF in Chro
[Objective]To study the effects of flavonoids from Scutellaria stem and leaf (SSF) on the expression of NMDAR (N-methyl-......
Scutellaria baicalensis stem-leaf total flavonoid reduces neuronal apoptosis induced by amyloid beta
Scutellaria baicalensis stem-leaf total flavonoid might attenuate learning/memory impairment and neuronal loss in rats i......
雌性生殖干细胞的发现打破了传统的“固定卵泡理论”。研究表明,在人和小鼠卵巢中,该类细胞定位于卵巢表面上皮,并可在其中检测到O......
Pt-Sn cupported on MgAl2O4 spinel doped with Ca Li Ce weretested in propane dehydrogenation in the presence of steam Whe......
Aim: Anticonvulsant tolerance and dependence are two obstacles that restrict the clinical use of benzodiazepines (BDZ).......
