vincristine相关论文
Thermo-sensitive liposomes tri-loaded with doxorubicin,vincristine,and salinomycin for co-inhibition
Cancer stem cells (CSCs) have been studied as a target for overcoming drug resistance which plays an important role in t......
TreatmentofcorticosteroidresistantvasculartumorsassociatedwiththeKasabach-Merrittphenomeno
Objective Toinvestigatetheeffectivenessandapplicationoftransarterialembolizationplussystemicvincristineforthetreatmentof......
Autophagy-mediated HMGB1 release antagonizes apoptosis of gastric cancer cells induced by vincristin
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Objective Vincristine(VCR),a first line antineoplastic agent,often induces neuropathic pain,and currently no means is av......
Objective Chemotherapic drugs commonly induced peripheral neuropathic pain and limited its use in clinic.Fucoidan is an ......
A targeting liposomal structure by incorporating vincristine with dasatinib for treatment of invasiv
Recurrence of invasive breast cancer could arise from the residual cancer cells after comprehensive treatment.The residu......
Treatment of corticosteroid resistant vascular tumors associated with the Kasabach-Merritt phenomeno
...
Low Concentrations of Chloroquine and 3-Methyladenine Suppress the Viability of Retinoblastoma Cells
Background: To study the inhibition of retinoblastoma cell viability by two commonly usedautophagy inhibitors, chloroqui......
Medicinal plants are the most exclusive source of life saving drugs for the majority of the worlds populations.Plant......
目的探讨长春新碱调控RAS相关结构域蛋白2A(RASSF2A)去甲基化对卵巢癌细胞增殖的影响。方法将卵巢癌SKOV3细胞分为不同浓度长春新......
Synthesis of Phenoxazinone Derivatives and Antiproliferative Activities on Wild-type and Drug-resist
A series of novel phenoxazinone derivatives (1-6) were designed and synthesized for evaluating their antitumor activitie......
Currently there is considerable interest among oncologists to find anticancer drugs in Chinese herbal medicine (CHM). In......
In this paper,the relationship of intracellular acidification and apoptosis in Hela cells induced by vin-cristine sulfat......
目的构建长春新碱抗耐药性隐形脂质体,并考察其在大鼠体内的药动学。方法采用硫酸铵梯度法制备长春新碱抗耐药性隐形脂质体;将Spra......
目的:探讨RNA干扰(RNA interference,RNAi)技术沉默凋亡抑制蛋白Apollon基因表达联合中药川芎嗪(tetramethylpyrazine,TMP)能否增......
An Open-Label Study of Pegylated Liposomal Doxorubicin,Vincristine, and Reduced-Dose Dexamethasone C
OBJECTIVE Though doxorubicin is highly activein the treatment of multiple myeloma, its toxicityprofile limits its thera......
Background Renal sympathetic denervation is a promising technique for the treatment of resistant hypertension. We evalua......
Objective To evaluate the efficacy and safety of etoposide, methotrexate, actinomycin D, vincristine and cyclophosphami......
AIM:To isolate and clone the vincristine-resistine-relatedgenes in gastric cancer SGC7901 cell line and to clarify them......
Specific myeloprotection via multidrug resistance 1 gene controlled by aminopeptidase N myeloid prom
In the treatment of tumor patients introduction of multidrug resistance genes into hematopoietic cells has been reported......
AIM:To investigate the expression level of ZNRD1 gene ingastric cancer cells SGC7901 and gastric cancer MDR(multidrug r......
Increasing the dosage of vincristine: a clinical and pharmacokinetic study of continuous-infusion vi
BACKGROUND: Vincristine (VCR) is widely used to treat patients with malignant disease; among the patients treated with ......
Effect of mitogen-activated protein kinase signal transduction pathway on multidrug resistance induc
AIM:To investigate the correlation between mitogen-activated protein kinase (MAPK) signal transduction pathwayand multi......
AIM:To investigate the reversal effect of neferine on multidrugresistance in human gastric carcinoma cell line.METHODS:......
Wild type p53 increased chemosensitivity of drug-resistant human hepatocellular carcinoma Bel7402/5-
AIM: To study the effect of wild type (wt) p53 gene transfection on drug resistant human hepatocellular carcinoma (HCC) ......
1 引 言肿瘤是威胁人民生命健康的严重疾病之一。临床上除手术、放射治疗外 ,化学治疗也是挽救病人生命的重要手段[1] 。在肿瘤......
Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VC
Aim: To investigate the reversal effects of curcumin on multidrug resistance (MDR) in a resistant human gastric carcino......
AIM: To verify whether P-glycoprotein (P-gp) could induce cell resistance to apoptosis by inhibiting caspase-8 and caspa......
多发性骨髓瘤（ MM）伴发周围神经病变主要表现为进行性、对称性的四肢远端感觉及运动障碍。目前对于周围神经病变发生的机制尚不清楚，......
目的评价长春新碱(vincristine，VCR)治疗卡波西样血管内皮瘤(Kaposiform hemangio endothelioma，KHE)伴K-M现象(Kasabach-Merritt ph......
目的 探讨可溶性耐药相关钙结合蛋白(Sorcin)在胃癌耐药中的作用及机制.方法 采用逆转录(RT)-PCR法扩增Sorcin cDNA片段编码区序列......
ＩＮＴＲＯＤＵＣＴＩＯＮＴｈｅｃｏｍｂｉｎｅｄｃｈｅｍｏｔｈｅｒａｐｙｆｏｒｍａｌｉｇｎａｎｔｃａｒｃｉｎｏｍａｉｓｄｅｓｉｒｅｄｔｏｐｒｏｄｕｃｅｅｆｉｃａｃｉｏｕｓｓｙｎｅｒｇｉｓｍｂｅｔｗｅｅｎｅａｃｈｄｒｕｇ，ａｌｅｖｉａｔｅｓｉｄｅｅｆｆｅ...
INTRODUCTIONThecombinedchemotherapyformalignantcarcinomaisdesiredtoproduceeficacioussynergismbetweeneachdrug,alevia......
介绍利用中效原理设计电脑程序分析化疗联合用药体外药敏实验的效应。本程序所需要的试验次数较少，不但能确定两种药物是否协同，而且......
Expression and function of classical protein kinase C isoenzymes in gastric cancer cell line and its
AIM:To investigate the expression and function of classicalprotein kinase C(PKC)isoenzymes in inducing MDRphenotype in ......
AIM:To study the effect of copper transporting P-typeATPase in copper metabolism of hepstocyte andpathogenesis of Wilso......
BACKGROUND:Extramedullary pancreatic plasmacy- toma treated with bortezomib is rarely reported. METHODS:We admitted a 53......
Objective: The combination of highly active antiretroviral therapy (HAART) and chemotherapy with ABV regimen (doxorubici......
Small cell carcinoma of the cervix(SCCC)belongs to the neuroendocrine carcinomas,and it is a rare gynecological tumor of......
Secondary pancreatic involvement by a diffuse large B-cell lymphoma presenting as acute pancreatitis
Diffuse large B-cell lymphoma is the most common type of non-Hodgkin’s lymphoma. More than 50% of patients have some si......
Reversal of multidrug resistance in vincristine-resistant human gastric cancer cell line SGC7901/VCR
AIM: To investigate the reversal effect of LY980503, a benflumetol derivative, on multidrug resistance in vincristine (V......
不推荐丙卡巴肼(procarbazine)、洛莫司汀(lomustine)和长春新碱(vincristine)联合化疗(PCV方案)用于间变性少突胶质细胞瘤和星形......
AIM:Vincristine is one of the most commonly used chemotherapeutic drugs to treat a variety of malignant diseases,includi......
Objective: To investigate the presence of different phytoconstituents in Mangifera indica(M. indica) peel and evaluate i......
Background and Objective:Chemotherapy is the main treatment for colon cancer,while multidrugresistance is the main reaso......
长春新碱(vincristine,VCR)已被广泛应用于恶性肿瘤的化疗30年。由于常规剂量的 VCR 对骨髓的抑制作用较轻,因此常用于联合化疗的......
目的：研究粉防己碱（Ｔｅｔ）和阿霉素（Ｄｏｘ）或长春新碱（Ｖｉｎ）联合用药在体外分别对人乳腺癌细胞ＭＣＦ７及其抗Ｄｏｘ细胞ＭＣＦ７／Ｄｏｘ或人口腔上皮样癌细胞ＫＢ及其抗Ｖｉｎ细胞ＫＢＶ２００的相互作用......
Background The development of the targeted signal transduction inhibitor STI571 has prompted us to treat chronic myeloid......
AIM To filtrate breast cancer resistance protein(BCRP)-mediated resistance agents and investigate the mechanism,so as to......
Antioxidant,antibacterial and cytotoxic effects of the phytochemicals of whole Leucas aspera extract
Objective:To investigate the antioxidant,antibacterial and cytotoxic activity of whole Leucas aspera(Labiatae)(L.aspera)......
