sequencing相关论文
36. Study on p16INK4a and p15INK4b genes of human bronchial epithelial cells malignantly transformed
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The high diversity of SARS-CoV-2-related coronaviruses in pangolins alerts potential ecological risk
Understanding the zoonotic origin and evolution history of SARS-CoV-2 will provide critical insights for alerting and pr......
RNA sequencing (RNAseq) can reveal gene fusions, splicing variants, mutations/indels in addition to differential gene ex......
Next-generation sequencing technologies have significantly accelerated the identification of disease-causing mutations a......
RNA modification has been recognized as a pivotal regulator that affects gene expression in a post-transcriptional manne......
Jatropha is a non-edible,important bioenergy plant,which can grow in marginalized land.The seeds possess about 36％ oil an......
扩增子测序是目前用来衡量微生物多样性时使用最广泛的测序手段.因为其扩增的需要,所以选择合适的特定引物是必需的,且其对结果影......
Microglia activation, classification and microglia-mediated neuroinflammatory modulators in subarach
Subarachnoid hemorrhage is a devastating disease with significant mortality and morbidity, despite advances in treating ......
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Nanomotor Channel Size Conversion of Phi29 DNA-Packaging Nanomotor for Single-pore Sensing of Single
Nanopores have been utilized to detect the morphology of polymers, including DNA and RNA.The uniform channel size formed......
Sequencing and analyzing the genome of Pseudomonas Fluorescens GcM5-1A:a pathogen living in the surf
Pseudomonas Fluorescens are gram negative bacteria that inhabit soil,water and water surface.Recently they were also det......
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De novo sequencing transcriptome and different expression genes in ovarian tissue of Sichuan White g
High-throughput RNA sequencing was performed for comprehendsively analyzing the transcriptome of the geese.A total of 28......
The isotope labeling strategies had a long and significant impact on the studies of nucleic acids sequencing....
De novo transcriptome sequencing in Dioscorea composita to infer the biosynthesis pathway of flavono
Dioscorea composita is an important medical and energy plant used for extracting different biological active substance a......
TAS-ELISA detection samples which was infected banana bunchy top virus (BBTV), cloning two genome of BBTV HaiKou 2 and B......
Identification of germline variants that predispose to breast cancer in Chinese Han population by wh
Objective Triple-negative breast cancer(TNBC),the most aggressive subtype of breast cancer,defined by the absence of est......
Objective Multiple myeloma(MM)is characterized by an expansion of a clonal plasma cell population.presence of a serum or......
Accurate genotyping of hepatitis C virus through nucleotide sequencing and identification of new HCV
Nucleotide sequencing of the phylogenetically informative region of NS5B remains the gold standard for HCV genotyping....
Identification of the germline variants that predispose to breast cancer in Chinese Han population b
Objective Background: Triple negative breast cancer(TNBC),the most aggressive subtype of breast cancer,defined by the ab......
Objective: To explore the correlation between PEAR1 genetic polymorphism and PTE.Material and methods: The variant loci ......
Objective: Bladder cancer and renal cancer are common malignancies in the urological system.The aims of the present stud......
Listeria monocytogenes WaX12 Isolated From China Contained Five Prophages Revealed by Comparative Ge
[Introduction]Listeria monocytogenes,a food-borne pathogen,can cause listeriosis via contaminated food products.Listerio......
Comparison of First Void Urine with Urethral Swabs for Detection of Ureaplasma in Male Patients with
A total of 96 non-duplicate male patients with urogenital infections from 2015 to 2016 were included,they were randomly ......
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The antifungal caspofungin is a semi-synthetic derivative of the lipohexapetide pneumocandin B_0 produced by the fungus ......
Identification of the differentially expressed genes in rice in response to the pathogen Rhizoctonia
Rice sheath blight is an important disease caused by the necrotrophic pathogen Rhizoctonia solani. However,the details o......
目的分析广西地区原发性肉碱缺乏症(primary carnitine deficiency，PCD)新生儿筛查代谢谱和基因变异谱，了解广西地区人群的患病率和......
Educational facilities serve as community hubs and consequently hotspots for exposure to pathogenic microorganisms.There......
Genetic mutations associated with sensitivity to neoadjuvant chemotherapy in metastatic colon cancer
BACKGROUND Colorectal liver metastases(CLM)occur in 15%-30%of patients with colorectal cancer(CRC).Advancements in next ......
Usefulness of metagenomic next-generation sequencing in adenovirus 7-induced acute respiratory distr
BACKGROUND Direct metagenomic next-generation sequencing(mNGS)of clinical samples is an effective method for the molecul......
The sequencing of complete human genome revolutionized the genomic medicine.However,the complex interplay of gene-enviro......
BACKGROUND A palatal radicular groove is an unusual developmental deformity of the tooth,which may serve as a channel li......
Unusual immunohistochemical“null”pattern of four mismatch repair proteins in gastric cancer:A case r
BACKGROUND Immunohistochemical(IHC)staining for mismatch repair(MMR)proteins is useful for gastric cancer treatment and ......
FGFR2-TSC22D1,a novel FGFR2 fusion gene identified in a patient with colorectal cancer:A case report
BACKGROUND The FGFR signaling pathway is activated in multiple tumor types through gene amplifications,single base subst......
Gastrointestinal-type chemotherapy prolongs survival in an atypical primary ovarian mucinous carcino
BACKGROUND Primary ovarian mucinous carcinoma is a rare histologic subtype of epithelial ovarian carcinoma and exhibits ......
Dysbiosis of the gastric microbiome is involved in the development of gastric cancer(GC).A number of studies have demons......
BACKGROUND Alport syndrome(ATS)is a rare hereditary disease caused by mutations in genes such as COL4A3,COL4A4,and COL4A......
Identification of COL3A1 variants associated with sporadic thoracic aortic dissection: a case-contro
Thoracic aortic dissection(TAD)without familial clustering or syndromic features is known as sporadic TAD(STAD).So far,t......
Chromosome-level genome of Himalayan yew provides insights into the origin and evolution of the pacl
Taxus,commonly known as yew,is a well-known gymnosperm with great ornamental and medicinal value.In this study,by assemb......
Alternative splicing of eukaryotic precursor(messenger)RNAs in the nucleus not only increases transcriptomic complexity,......
In December 2017, two suspected outbreaks of <em>Yersinia enterocolitica </em>4/O:3 were notified in Finland. We analyze......
Use of DNA metabarcoding of bird pellets in understanding raptor diet on the Qinghai-Tibetan Plateau
Background:Diet analysis is essential to understanding the functional role of large bird species in food webs.Mor-pholog......
Alzheimer’s disease(AD)is the most common neurodegenerative disorder and there is currently no cure.Neural circuit dysf......
BACKGROUND Chlamydia psittaci(C.psittaci)is a gram-negative intracellular parasitic pathogenic bacterium that can infect......
The brown marmorated stink bug, <i><span style=\"font-family:Verdana;\">Halyomorpha halys</span></i><span style=\"......
Objective To investigate the genetic causes of sudden sensorineural hearing loss(SSNHL)patients in China.This study focu......
Rapid diagnosis of disseminated Mycobacterium mucogenicum infection in formalin-fixed, paraffin-embe
BACKGROUND Mycobacterium mucogenicum(M.mucogenicum)belongs to the group of rapidly growing Nontuberculous mycobacteria.T......
出生缺陷与罕见病已成为重大公共卫生问题，早期防控和阻断是目前最有效的干预措施。近年来随着高通量测序等基因组检测技术的飞速发......
