opioid相关论文
Objective: To evaluate the antinociceptive activity of perillyl acetate in mice and in silico simulations. Methods: The ......
目的:探讨术中持续静脉输注亚麻醉剂量艾司氯胺酮对胸腔镜手术患者术后阿片类药物镇痛消耗量的影响。方法:选取郑州大学第一附属医......
Standardized Treatment of Chinese Medicine Decoction for Cancer Pain Patients with Opioid-Induced Co
...
N-acetylaspartylglutamate Inhibits Heroin Self-Administration and Heroin-Seeking Behaviors Induced b
Activation of presynaptic group Ⅱ metabotropic glutamate receptors (mGluR2/3) inhibits drug reward and drug-seeking beh......
The opioid epidemic continues to be a serious public health concern.Many have pointed to prescription drug misuse as a n......
ParecoxibsodiumandLocalInfiltrationAnalgesiaforPostoperativePainManagementAfterTotalKnee
Purpose: Effective analgesia can substantially affect rehabilitation and ultimate outcome after total knee replacement.H......
Neutrophil-to-lymphocyte ratio as indicator to opioidinduced immunosuppression after thoracoscopic s
Objective Inflammation seems to be one of the most important perioperative factors of recurrences,at least in breast,lun......
Early repeated AMD3100 administration dose-dependently improves neuropathic pain in rats after L5 sp
Multiple lines of evidence suggest that AMD3100 has analgesic effects on many pathological pain states, including periph......
Small amounts of free radicals are known to participate in the signaling pathway in myocardial preconditioning, a proces......
The optimum dose of intranasal remifentanil for laryngeal mask airway insertion during sevoflurane i
Objective:The purpose of this study was to determine the optimum dose of intranasal remifentanil required to produce sat......
AIM This study was designed to assess the antinociceptive effect of verticinone and to evaluate the involvement of opioi......
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Effects of Pre-Operative Single Dose Gabapentin on Postoperative Pain Following Total Abdominal Hyst
<b>Background & Aims:</b> The multimodal analgesia provides superior pain relief and reduces opioid consumption and its ......
Neuropathic pain is a chronic pain caused by peripheral or central nervous system injury or diseases that affect the som......
Endomorphin analogues with mixed μ-opioid receptor agonismδ-opioid receptor antagonism and lacking β
Analogues of endomorphin(Dmt-Pro-Xaa-Xaa-NH2)modified at position 4 or at position 4 and 3,and tripeptides(Dmt-Pro-X......
Objective:To investigate the effects of 30-day treatment with therapeutic dose equivalent levels of tramadol on serum te......
内源性阿片肽系统(e n d o-genous opioid system)有参与疼痛过程的调节、对应激的反应以及止痛治疗的作用。最近人体影像学显示其......
Objective: To investigate the analgesic effects of Nourishing yin and Unblocking meridians Receipe (NUR) combined with o......
Nociceptin effect on intestinal motility depends on opioidreceptor like-1 receptors and nitric oxide
AIM: To study the effect of the opioid-receptor like-1(ORL1) agonist nociceptin on gastrointestinal(GI)myenteric neurotr......
·AIM: To investigate the impact of cirrhosis on retinal morphology and to evaluate the role of endogenous opioids as a ......
AIM:To characterize an alcohol and high fat diet induced chronic pancreatitis rat model that mimics poor human dietary c......
Pain in chronic pancreatitis(CP) shows similarities with other visceral pain syndromes(i.e.,inflammatory bowel disease a......
To study the structure-activity relationship of endomorphins (EMs), the action of opioid receptor binding (AORB), analge......
<正> The multiplicity of opiate receptors has turned out to be the most attractive to workers in this field, since Marti......
<正> The finding that acupuncture analgesia could be blocked by naloxone provided ample evidence for the participation o......
<正> Goldstein et al. found in the porcine pituitary a potent opioid peptide dynorphin composed of 17 amino acids with l......
AN IRREVERSIBLE OPIOID RECEPTOR AGONIST WITH ULTRALONG ANALGESIC EFFECT: 7a-BIS (β-CHLORO ETHYL) AMI
<正> To characterize the multiple types of opioid...
Sequence and modified group analysis on C-terminal modified analogs of endomorphin-2 using electrosp
In this paper, a series of C-terminal modified analogs of endomorphin-2 is investigated using ESI-FT-ICR-MS. Some b, y″......
Objective To analyse the potential involvement of the opioid receptor gene expression in the mechanisms of the analgesic......
Influence of morphine on levels of type Ⅱ inhibitory guanine nucleotide binding protein in primary h
BACKGROUND: The pharmacological action of opioid drugs is related to signal transduction of inhibitory guanine nucleotid......
目的:比较16周自发性高血压大鼠(SHR)和对照组Wistar-Kyoto(WKY)大鼠中枢神经系统中与血压调节有关的核团内阿片受体密度的变化.方......
AIM: To characterize the antinociceptive action of the novel melatonin receptor(MT) agonists, Neu-P11 and Neu-P12 in ani......
本研究采用全细胞膜片钳技术观察了SNC162 (一种选择性δ阿片受体激动剂)对大鼠心室肌细胞L型钙电流(L-type Ca2+current, ICa-L)......
Ohmefentanyl has significant inhibitory actions on the electrically evoked contractions of guinea pigileum and mouse va......
MUTUAL POTENTIATION OF THE ANA-LGSIC EFFECT OF MORPHINE MET-ENKE-PHALIN AND DYNORPHIN AND THEIR ANTA
The present study deals primarily with the antagonistic effect of Naloxone(NX) against mutual potentiation of morphine ......
substituted hexahydro-1H-1,4-diazepine analogues were synthesized starting from N,N?-dibenzyl-1,3-propylene diamine and ......
Sidiming attenuates morphine withdrawal syndrome and nitric oxide (synthase) levels in morphine-depe
The present study analyzed the effects of Sidiming, a Chinese herbal compound, on withdrawal syndrome, body weight loss,......
Traditional Chinese Medicine-facilitated switch from methadone to buprenorphine-naloxone for treatme
The switch from methadone to buprenorphine-naloxone for individuals with heroin dependence is associated with several ob......
目的探讨纳布啡联合舒芬太尼用于剖宫产术后经静脉患者自控镇痛(Patient-controlled Intravenous Analgesia，PCIA)的效果。方法选择......
δ-阿片受体(DOR)是一类具有7个跨膜区域的抑制性G蛋白偶联受体，是一种经典镇痛药物，广泛存在于中枢系统和外周系统中。研究表明，阿片......
重症加强治疗病房（ICU）患者常伴有急性疼痛，而严重的疼痛可能衍生出一系列生理反应，影响患者预后。随着现代医学的不断进步，镇痛治疗策......
目的探讨地佐辛用于高海拔地区(平均海拔4 500 m以上)腹腔镜胆囊切除术后患者镇痛的有效性和安全性。方法研究设计为开放性随机对......
AIM: To demonstrate the change and effect of nociceptin/orphanin FQ in the colon of rats with cathartic colon.METHODS: T......
β-funaltrexamine differentially modulates chemokine and cytokine expression in normal human astrocyt
Aim: Emerging evidence implicates astrocyte/microglia dysregulation in a range of brain disorders, thereby making glial ......
30 year old female now para 1 presented to the Emergency Department with nausea, vomiting, and abdominal pain 6 days aft......
Pain relief by xenograft of subarachnoid microencapsulated bovine chromaffin cells in cancer patient
The bovine chromaffin cells (HCC) implanted into the subarachnoid space can release analgesic substances such as opioid......
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The purpose of this study was to investigate the blood levels of methadone in participants receiving methadone for the t......
CCK RECEPTOR ANTAGONIST L-365,260 POTENTIATED ELECTROACUPUNCTURE ANALGESIA IN WISTAR RATS BUT NOT IN
Cholecystokinin octapeptide (CCK-8) has been shown to be a neuropeptide with potent anti-opioid activity. Previous studi......
