anticancer相关论文
Light amplified oxidative stress in tumor microenvironment by carbonized hemin nanoparticles for boo
Photodynamic therapy (PDT), which utilizes light excite photosensitizers (PSs) to generate reactive oxygen species (ROS)......
Novel lysosome-targeted anticancer fluorescent agents used in zebrafish and nude mouse tumour imagin
The design of three novel fatty nitrogen mustard-based anticancer agents with fluorophores incor-porated into the alkene......
Chemical Composition, Anticancer, Anti-neuroinflammatory, and Antioxidant Activities of the Essentia
Objective:To study the chemical composition,anticancer,anti-neuroinflammatory,and antioxidant activities of the essentia......
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Effects of Banxia Xiexin Decoction（半夏泻心汤）on Cisplatin-Induced Apoptosis of Human A549 Lung Cancer Ce
Objective:To examinie the synergistic effects of Banxia Xiexin Decoction（半夏泻心汤,Known as Banhasasim-tang in Korean) e......
A series of new hybrids of dehydroandrographolide (TAD),a biologically active natural product,bearing nitric oxide (NO)-......
Pharmaceutical research has focused on the discovery and development of anticancer drugs.Clinical application of chemoth......
Garcinia,a kind of dry resin secreted by Garcinia hanburyi Hook.F.G.,is a traditional Chinese medicine with various biol......
Growth inhibitory effect of 4-phenyl butyric acid on human gastric cancer cells is associated with c
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Controlled drug release is critical for improving anticancer efficacy and reduing side effects of drug delivery systems[......
Chitosan-Based Multifunctional Nanocomposites for Cancer Therapy:Synthesis,Characterization,and Func
In this study, the multifunctional nanocomposites (MFNCs) as drug carriers are prepared by cross-linking reaction of cat......
Nucleolin targeting AS1411 aptamer modified pH-sensitive micelles: a dual-functional strategy for pa
Targeted drug delivery coupled with rapid drug release in cytoplasm is a powerful strategy to enhance efficacy and reduc......
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Extraction, identification, and antioxidant and anticancer tests of seven dihydrochalcones from Malu
Five dihydrochalcones including phlorizin, trilobatin, 3-hydroxyphloridzin, sieboldin (3-hydroxytrilobatin) and phloreti......
Successful therapy of cancer has been seriously hindered by the insolubility and instability of antitumor drugs,and more......
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Ferns are well-known traditional Chinese medicinal herbs.Dryoathyrium boryanum(Willd.)Ching.exhibited strong antioxidant......
Chinese ginseng (Panax ginseng C.A.Meyer), have a long history of use and widespread research in the world.Due to the sc......
In Vivo Evaluation of Cisplatin-loaded PEG-PCL Block Copolymeric Nanoparticles for Anticancer Drug D
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The Bcl-2 protein family works as vital regulators in intrinsic cell death pathway.Myeloid cell leukemia 1(Mcl-1),a pros......
A series of naphthalimide nitrogen mustards as anticancer agents were developed,their structures were characterized by 1......
Pyrimidines play an important role in the drug discovery process,and have considerable pharmacological and chemical sign......
Anticancer Activities of Polyynes from the Root Bark of Oplopanax horridus and Their Acetylated Deri
Six polyynes (OH-1～6), some of which are naturally occurring acetylated, had been isolated and identified from the root b......
The analgesic and anticancer effects of minimally toxic fraction from Liu-shen-Wan and the underlyin
Aim: Liu-Shen-Wan (LSW), an ancient preparation used to treat localized infection with pain, was reported to possess ant......
School of Pharmaceutical Sciences,Zhengzhou University,Zhengzhou 450001,China Five and six membered aza-heterocyclic sys......
pH and Redox Dual Responsive Polymeric Micelles for Enhanced Intracellular Drug Release in Cancer Th
To improve the intracellular drug release and anticancer efficacy in cancer therapy, in the present study, a pH and redo......
Polyporus umbellatus (Pers.) Fries: traditional uses, phytochemistry, pharmacology, pharmacokinetics
Aim: Polyporus umbellatus (Pers) Fries (Polyporaceae), a widely used traditional Chinese medicine, was known as Zhu Ling......
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Early metastasis is still the most recalcitrant factor in the treatment of lung cancer patients.By analyzing the structu......
In this research,some of the new inorganic complexes of first series transition metals complexes were synthesized.These ......
Screening Apolar extracts from South Australian marine sponges for Cytotoxicity properties against t
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Particle size effect of curcumin nanosuspensions on the in-vitro anticancer activity,cellular uptake
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Curcumol triggers apoptosis of p53 mutant, triple-negative human breast cancer cell MDA-MB 231 via a
Background: Triple-negative breast cancer (TNBC) remains a major challenge clinically due to a lack of biological target......
Jaridonin, a novel anticancer drug, induced human gastric cancer cell line MGC-803 autophagy and Its
Aim: Jaridonir, a novel ent-kaurane diterpenoid compound from Isodon Rubescens in our laboratory.We designed the current......
Bacillus Calmette-Guerin (BCG) is the only available vaccine against tuberculosis, it is an attenuated live vaccine prep......
Potentiating effect of citral on anticancer activities of doxorubicin, vincristine, and etoposide In
Aim: Citral is a mixture of terpene aldehydes in essential oils of several plants used for cooking such as lemongrass.Th......
Limonoids are typical secondary metabolites,abundant in citrus fruit and other plants found in the Rutaceae and Meliacea......
Preliminary biological data on 7-anilino-6-azaindoles(8–11)suggested that hydrophobic substituents at C-7 contribute to......
ConformationallyConstrained Tetrahydroisoquinolines:Design,Synthesis and SAR Study as PARP-1Inhibito
Poly(ADP-ribose) polymerase-1(PARP-1)(ADP,adenosine diphosphate) is a 113kDanuclear protein that is involved in the sign......
Angiogenesis is involved in the development,progression and metastasis of various human cancers.Herein,we report the dis......
Scutellaria Barbata D.Don Inhibits Colorectal Cancer Growth via Suppression of Multiple Signaling Pa
The pathogenic mechanisms underlying cancer development are complex and heterogeneous,involving multiple cellular signal......
Paclitaxel-loaded poly(ethylene glycol)-block-poly(γ-cholesterol-L-glutamate)nanoparticles for loadi
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Anticancer activity and computational modeling of ternary Cu(Ⅱ)complexes with 3-indoleacetic acid an
Metal complexes have been widely studied as potent proteasome inhibitors.The 20S proteasome,the main component of the ub......
Iridium(Ⅲ)complexes of general formula [Ir(bpy)2(N^N)Cl2],where N^N= 2-(pyrazin-2-yl)naphtho[1,2-e][1,2,4]triazine,1,or......
Mitochondria participate in multifarious cellular functions,especially in energy production and cell apoptosis....
Design,Synthesis and Anticancer Activity of Pyrimidine Modified Biaryl Derivatives Targeting PD-1/PD
Programmed death receptor-1(PD-1)is a 50-55 kDa type Ⅰ transmembrane glycoprotein and is a member of the immunoglobulin......
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A Cyclometalated Iridium (Ⅲ) Complex which targets Mitochondria for the Highly Efficient Photodynami
Cancer is one of the leading causes of death globally,and the development of anticancer agents is therefore of paramount......
