Heat shock protein 90(Hsp90)is the most common molecular chaperone that controls the maturation of many oncoproteins cri......

Objective:Colorectal cancer(CRC)is one of the most lethal and prevalent malignancies world-wide.Currently,surgery,radiot......

姜黄素是从姜黄的根茎中提取的一种天然色素，在抗癌、抗炎、抗氧化、抗肿瘤、调脂降糖、保护神经系统等药理方面具有显著的疗效，并且......

目的 探讨Curcumin协同ABT-737对肝癌7404细胞上皮间质转化(epithelial-mesenchymal transition,EMT)的抑制作用及机制研究.方法 2......

Dexanabinol (HU-211) is an artificially synthesized cannabinoid derivative that exerts neuroprotective effects through a......

Alzheimer\'s disease is a progressive brain disorder and complex mechanisms are involved in the physiopathology of Alz......

Objective:To investigate the potential mechanisms that curcumin reverses 5-fluorouracil (5-FU) multidrug resistance (MDR......

...

...

...

...

Glioblastoma is the deadliest neoplasm with the worst 5-year survival rate among all human cancers.Autophagy promotes au......

...

...

...

Islet transplantation is one of the therapeutic approach for diabetic patients.For an average-size person (70 kg),a typi......

The tumour tissue is characteristic of an acid-microenvironment (pH~6.8).This feature as well as the low pH milieu (4.5-......

Angiostatin is one of the first few endogenous antiangiogenic agents that are able to restrain tumor growth and transfer......

Curcumin (Cur),an active ingredient from the rhizome of the plant,Curcuma longa,has wide anticancer activities.However,d......

...

Introduction: Osteoarthritis(OA)is an inflammatory disease of load-bearing synovial joints that is currently treated wit......

Objective At present,the treatment methods of liver cancer are radical surgical resection,local ablation,arterial chemoe......

...

Objective Chemotherapy is one of most important treatment for human cancers.However, its side effects such as intestine ......

Purpose: The effect of single and multiple doses of piperine on the bioavailability and pharmacokinetics of curcumin was......

AIM During the inflammatory processes in CNS,activated microglia can be induced by many factors.Activation of microglia ......

[Objective] To determine the clinical effect of curcumin on coronary artery lesion in pediatric patients with Kawasakis ......

Aim Large conductance Ca2+activated potassium channel (BK), expressed in the distal nephron, mediates potassium secretio......

Psoriasis is a benign, chronic skin disease characterized by keratinocyte hyperproliferation and abnormal differentiatio......

...

Objective: The present study aims to investigate that LED light-activated curumin induced the damages of Escherichiacoli......

Objective In the present study, we investigated whether curcumin have therapy value in testicular cancer and examined th......

...

OBJECTIVE Hepatocellular carcinoma (HCC) is the most common cause of cancer-related mortality, with high incidence rates......

...

Major depressive disorder is a neuropsychiatric disorder with few approaches.The application of nontargeted antidepressa......

The detection property of natural drug-curcumin (1) was firstly reported by us.Experimental details showed 1 acts as an ......

This research aims to combine traditional Chinese medicine theory with a new drug delivery system,hoping the drug carrie......

Objective To explore the possible effects of curcumin on hyperalgesia of sleep deprivation rats and further to understan......

This work presents a sensitive voltammetric method for determination of curcumin by using a electrochemically reduced gr......

Chemotherapy is widely used in various cancer treatments.However,current cancer chemotherapy has a major limitation:lack......

As one of the most common malignancies in males, prostate cancer is dying to precise interventions targeting signaling p......

Curcumin,the yellow pigment present in the Indian spice turmeric derived from Curcuma longa,associated with curry powder......

In this study, a novel liposome-loaded microbubbles based on biomimetic polymer of blood cell membrane, N-Cholesteryl he......

There is abundant evidence suggesting the relevance of glutamate to depression and antidepressant mechanisms.Curcumin, a......

OBJECTIVE To prepare Curcumin-loaded methoxy polyethylene glycol-polylactic acid (mPEG-PLA) nanoparticles (CUR-mPEG-PLA-......

Objective To prepare Curcumin Long-circulating Liposomes (Cur-LCL), characterize their physicochemical properties and to......

...

In this study, our aim was to develop an injectable drug reservoir to provide sustained, pH-sensitive curcumin-loaded ke......

Aim To construct a novel double liposome (DLP) formulation for combined delivery and evaluate the pharmacokinetic proper......