indole相关论文
报道了一种三甲基溴硅烷促进的通过碳-碳键交叉偶联反应合成N-甲基吲哚二聚体的方法.在温和条件下以最高95％的收率方便地合成了一系......
OG-PP06:Asymmetric Construction of Polycyclic Indoles via Olefin Cross-Metathesis/Intramolecular Fri
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Water-Medium C-H Activation over a Hydrophobic Perfluoroalkane-Decorated Metal-Organic Framework Pla
Direct construction of C-C bond from inert C-H bond is a highly efficient and sustainable strategy in synthesis of aryla......
Enantioselective C-H Functionalization of Indoles with α-Aryl-α-diazoacetates Catalyzed by NCN Bis(i
Pincer iridium complexes have been widely used as catalysts in organic transformations.In particular,a variety of achira......
Synthesis of Fused and Bridged Cyclic Pyrrolo[3,4-a]carbazoles via NH4I Pomoted Three-component Reac
The tetrahydrocarbazole architecture is a privileged heterocyclic ring system.It not only widely exists in various natur......
Design,Synthesis,and Structure-Activity Relationship of Novel Indole Derivatives as Potent Akt Inhib
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Malignant tumor is a life-threatening disease worldwide and the number of tumor patients is still increasing year by yea......
Indoles and indolines constitute prevalent structures in nature products and biological chemistry.1 Important contributi......
Synthesis of Fused Indoline Heterocycles via Dearomatization of Indoles with α-Bromohydrazones Under
Indolines are prevalent in a huge number of natural products and alkaloids1.They have extensive value in the fields of a......
Indoles derivatives have received much attention as building blocks for the synthesis of many natural products and other......
Palladium-Catalyzed Dearomatizing Coupling of Aryl Halides with Furfural Tosylhydrazones:A Novel Acc
The indole and thiophene structure is probably the heterocyclic nucleus that concentrates the most interest because of i......
Enantioselective Dinuclear Zinc-Catalyzed Friedel-Crafts Alkylation of Indoles with Ethyl Trifluorop
Indole is a privileged compound in pharmaceutical fragrance,agrochemicals,pigment and material scienceand over the past ......
Design, synthesis and biological evaluation of 7-nitro-1H-indole-2-carboxylic acid derivatives as al
A series of novel indole derivatives was synthesized as inhibitors of fructose-1,6-bisphosphatase (FBPase).Extensive str......
作为开发新型有效抗癌药物的进一步工作,采用分子杂交策略和路易斯酸催化偶联反应设计合成了一系列新型喹啉-吲哚类化合物.使用噻......
Synthesis and biological evaluation of novel indole derivatives containing sulfonamide scaffold as p
Microtubule-targeted drugs play a critical role in various types of cancer therapy worldwide.In our study,a series o......
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Dearomatization of Indoles via Azido Radical Addition and Dioxygen Trapping to Access 2-Azidoindolin
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Atroposelective Construction of Axially Chiral Alkene-Indole Scaffolds via Catalytic Enantioselectiv
Atroposelective construction of axially chiral alkene-heteroaryl scaffolds is highly desired but challenging....
Four luminescent cyclometalated iridium(Ⅲ) dipyridoquinoxaline complexes appended with an indole moiety [Ir(N^C)2(N^N)]......
Indole cyanation via C-H bond activation under catalysis of Ru(Ⅲ)-exchanged NaY zeolite(RuY) as a re
Selective 3-cyanation of indoles was achieved under heterogeneous catalysis of Ru(Ⅲ)-exchanged NaY zeolite(RuY) as a re......
Schiff base-Cu(Ⅱ) complex is found to be an effective catalyst for the condensation reaction of indole with aldehydes u......
Benzosiloles fused to heterocycles such as thiophene,benzothiophene,and benzofuran,and indole-and benzosilole-fused dibe......
Design,synthesis and in vitro antibacterial activities of methyl-4-((substituted phenyl)[6H-indolo(2
A series of new methyl-4-((substituted phenyl)[6H-indolo(2,3-b)quinoxalin-6yl]methylamino)benzoate derivatives have been......
本文研究了通过CuI催化的分子内和分子间4-碘色氨酸衍生物的N-芳基化反应引入天然产物indolactam V的缬氨酸片段, 以完成其全合成,......
Sulfamic acid as a cost-effective and recyclable solid acid catalyst for Friedel-Crafts alkylation o
Sulfamic acid was proved to be a cost-effective and recyclable catalyst for Friedel-Crafts type reaction of indole with......
Two novel compounds 1-(4-fluorobenzyl)-4-chloro-(Z)-3-benzoylhydrazono-2-indolinone(1) and 1-(4-methoxybenzyl)-(Z)-3-ben......
Two new compounds(1 and 2)based on indole were successfully synthesized and characterized.They display highly selective ......
The adsorptive denitrogenation from fuels over three metal-organic frameworks(MIL-96(Al),MIL-53(Al)and MIL-101(Cr))was s......
Direct N-gem-difluorocyclopropylation of nitro-heterocycles by utilizing gem-difluorocyclopropyl tos
We have developed an efficient method to achieve N-gem-difluorocyclopropylation of N-heterocycles with the use of gem-di......
Efficient synthesis of functionalized hydroindoles via catalyst-free multicomponent reactions of nin
An efficient synthesis of hydroindeno[1,2-b]indoles is described via three-component reaction of ninhydrin and cycloalka......
Synthesis, structure, and catalytic activity of rare-earth metal amides with a neutral pyrrolyl-func
1 Representation of complexes and selected bond distances and bond angles Figure S1 Structure of complex 4. Hydrogen ato......
Synthesis and cytotoxic activities of a series of novel N-methylbisindolylmaleimide amino acid ester
A series of novel N-methylbisindolylmaleimides and natural amino acid conjugates were synthesized and evaluated for thei......
10 mol% CuI combined with the DMEDA ligand can efficiently catalyze the N-arylation of 2-arylindoles with aryl iodides a......
One-step co-electrodeposition of graphene oxide doped poly(hydroxymethylated-3,4-ethylenedioxythioph
A novel graphene oxide(GO) doped poly(hydroxymethylated-3,4-ethylenedioxythiophene)(PEDOTM)film has been achieved via on......
Synthesis of 3-acylindoles via decarboxylative cross-coupling reaction of free(N–H) indoles with α-o
A convenient and general method for acylation of free(N–H) indoles via palladium-catalyzed decarboxylative cross-coupli......
A new, convenient and excellent yield procedure for the preparation of bis(indolyl)methanes(BIMs) by Friedel–Crafts rea......
Catalytic conjugate addition of indole toα,β-unsaturated ketones by Co(ClO_4)-2·6H_2O/bis-Schiff bas
Co(ClO_4))_2·6H_2O/bis-Schiff base complexes promoted the conjugate addition of indole toα,β-unsaturated ketones unde......
Poly(4-vinylpyridinium) perchlorate has been used as an efficient solid acid catalyst for the synthesis of 3,3’-(arylme......
3-乙酰基-2-氯-1-(4-氯苄基)吲哚与胡椒醛通过超声辅助或无溶剂的Claisen-Schmidt缩合反应首次合成含胡椒环的吲哚查尔酮,即(E)-3-......
A facile and improved route for the synthesis of the orally active spiroindoline-based growth hormone secretagogue,MK-67......
Discovery and application of 6π-azaelectrocyclization to natural product synthesis and synthetic bio
While elucidating the inhibitory mechanism of a hydrolytic enzyme by aldehyde-containing natural product,we discovered a......
A ligand-controlled gold-catalyzed highly site-selective insertion of a carbene into carbonhydrogen bonds has been achie......
最经常使用的钯催化剂催化的新有点分子间的吲哚 C-H amidation 反应被开发了。当创新的氮来源和环境地良性的氮作为唯一的副产品......
Selective hydrogenation of unprotected indole to indoline over N-doped carbon supported palladium ca
Mesoporous N-doped carbon supported palladium catalyst Pd@CN0.132 was able to efficiently catalyze unprotected indole to......
目的研究山麻黄Ephedra equisetina内生真菌Myrothecium roridum LLY固体发酵产物的化学成分,并进行体外细胞毒活性研究。方法采用......
Highly efficient and regioselective thiocyanation of aromatic amines,anisols and activated phenols w
A new method employing magnetic nanoparticles Fe_3O_4 as a catalyst and H_2O_2 as a green oxidant is developed for the o......
Two new prenylated indole alkaloids,namely,dihydrocarneamide A(1) and iso-notoamide B(2),were isolated from the marine-d......
