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Design,synthesis and in vitro antibacterial activities of methyl-4-((substituted phenyl)[6H-indolo(2
A series of new methyl-4-((substituted phenyl)[6H-indolo(2,3-b)quinoxalin-6yl]methylamino)benzoate derivatives have been......
Synthesis of novel β-amino ketones containing a p-aminobenzoic acid moiety and evaluation of their a
The synthesis of two series of β-amino ketones containing a p-aminobenzoic acid moiety (TM-1 and TM-2) using a modified......
all diabetic patients should be screened for the early stage of diabetic nephropathy,because microalbuminuria has a grea......
Design,synthesis and in vitro evaluation of tetrahydropyrimidine-isatin hybrids as potential antitub
A series of 5-substituted-3-[{5-(6-methyl-2-oxo/thioxo-4-phenyl-1,2,3,4-tetrahydropyrimidin-5-yl)-1,3,4-oxadiazol-2-yl}-......
Design,synthesis,in vitro evaluation of tetrahydropyrimidine-isatin hybrids as potential antibacteri
A series of 5-substitued-3-(5-(4-(furan-2-yl)-6-methyl-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-1,3,4-thiadiazol-2......
Objective: To investigate the prevalence of fragile X syndrome in the Chinese. Methods: Fragile X syndrome was screened......
Thirteen thiomorpholine-bearing compounds were designed and synthesized as dipeptidyl peptidase IV(DPP-IV) inhibitors, w......
Twelve novel dithiocarbamates containing 1,2,3-trizaoles group were prepared via one step starting from organic halides,......
Increasing maternal age is the only etiological factor un-equivocally linked to Down’s syndrome in humans. The occ-urre......
Two phase transition compounds,diethylammonium 1,5-naphthalenedisulfonate(1)and cyclohexylammonium 1,5-naphthalenedisulf......
Synthesis,Crystal Structure and Antibacterial Activities of 4-Methyl-2-(4-methylphenyl)-5-(2-thiazol
4-Methyl-2-(4-methylphenyl)-5-(2-thiazolinyl)-1,3-thiazole, a novel compound, was synthesized by the annulation of 5-hyd......
Nine 5-aryl-2-methyloxazole derivatives were synthesized via gold-catalyzed alkyne oxidation.All of the compounds have b......
A series of novel calix[4]arene derivatives incorporating two triazolyl 1 3-diketo subunits in alternate positions at th......
Environmental stress screening (ESS) is a technological process to reduce the costly early field failure of electronic c......
Common variants of the UMOD promoter associated with blood pressure in a community-based Chinese coh
Hypertension is an important risk factor for chronic kidney disease. The kidney, in turn, has an important role in the r......
A distribution map of Pinus yunnanensis was made according to the data on geographical distribution of P.yunnanensis by ......
Four 4-monosubstituted pyrimidine pyridyl sulfonylureas were synthesized from pyridinesulfonamide and phenyl pyrimidyl- ......
AIM:To investigate the expression of c-myc target fromlaryngeal cancer cells(MTLC)gene in gastric carcinoma(GC)tissues ......
The mobility limited by cluster scattering in ternary alloy semiconductor quantum wire(QWR) is theoretically investigate......
Analysis of three types of triterpenoids in tetraploid white birches(Betula platyphylla Suk.) and se
Betulin, oleanolic acid, and betulinic acid are naturally occurring pentacyclic triterpenoids that have significant medi......
The electronic properties of zinc-blende B_xGa_(1-x)N alloys are comparatively investigated by employing both the Perdew......
[Objective] To establish and optimize the ISSR-PCR system satiable for Nerviliae fordii(Hance) Schltr. [Methods]Five fac......
[Objective] The research was aimed at identifying the optimum culture medium for the proliferation culture of Atractylod......
INHIBITION OF NASOPHARYNGEAL CARCINOMA AND EBV EARLY ANTIGEN INDUCTION BY CHINESE HERBS AND MARINE O
In this study,we have discovered two antineoplastic drugs,CH861 from Chinese medicinal herbs and MO871 from the marine ......
Nondriven Polymer Translocation Through a Nanopore: Scaling for Translocation Time with Chain Length
We investigated the dynamics of the passage for a polymer chain through a nanopore in the absence of any external drivin......
Stool antigen tests in the diagnosis of Helicobacter pylori infection before and after eradication t
Aim: To evaluate two enzyme immunoassay-based stool antigen tests, Premier Platinum HpSA and Amplified IDEIA HpStAR, and......
Molecular Epidemiological Study on Prevalence of Human Papillomaviruses in Patients with Common Wart
Objective To study the circulation,distribution,and genomic diversity of HPVs in common warts in Beijing area of China.M......
Objective To investigate the prevalence,character-istics and risk factors of fatigue in a large cohort of subjects with ......
Objective:To evaluate the prevalence of co-infection of hepatitis B and Plasmodia among potential blood donors in Benue ......
INTRODUCTION OF FOREIGN GENES INTO THE SEED EMBRYO CELLS OF RICE BY ELECTRO-INJECTION AND THE REGENE
The NPTII gene has been successfully transferred to the seed embryo cells of two rice varieties (Oryza sativa L. subsp. ......
Objective The study aimed to analyze the influencing factors of thrombolysis therapy in acute ischemic stroke patients w......
Efficacy of ursodeoxycholic acid alone or combined with immunosuppressant in primary biliray cirrhos
Objective To evaluate the efficacy of ursodeoxycholic acid(UDCA)alone or combined with immunosuppressant in primary bili......
Chinese audiences love the new crop of foreign and domestic 3-D films when China screened its first commercial 3-D film,......
Factors associated with early neurological deterioration after intravenous thrombolysis with altepla
Objective To investigate the risk factors of early neurological deterioration(END)after intravenous thrombolysis(IVT)in ......
Objective To investigate the frequency of autoimmune encephalitis(AE)in limbic encephalitis(LE)syndrome and compare its ......
To acquire the phage-displayed mimotopes which mimic the specificity of hepatitis B virus surface antigen (HBsAg), a ran......
Preparation of human single chain Fv antibody against hepatitis C virus E2 protein and its identific
AIM:To screen human single chain Fv antibody(scFv)against hepatitis C virus E2 antigen and identify its applicationin i......
A series of novel azasterols 8a―8h and 10a―10c were synthesized from the key intermediate 6 by acylation and deprotect......
The nucleocapsid protein (N protein) has been found to be an antigenic protein in a number of coronaviruses. Whether th......
AIM:To search for female contraceptive agents. METHODS: 2-Hydroxy-3-methyl-1, 4-naphthoquinone monosemicarbazone ( HMNQ......
A two-step zero-length cross-linking procedure using active esters was successfully adopted for conjugating en-rofloxaci......
The screening of isolates and the assay of biocontrol mechanisms of Trichoderma were studied systematically in laborat......
Objective:To investigate the antimalarial activity of ethanol extract of Aspilin africana (A.africana) leaf.Methods:The ......
OBJECTIVE:Plants produce a variety of useful bioactive materials that have been used to cure different ailments of human......
The forecast of anticancer targets of cryptotanshinone based on reverse pharmacophore-based screenin
Anticancer targets of cryptotanshinone were evaluated and rapidly forecasted with PharmMapper, a reverse pharmacophore-b......
The active site of 3CL proteinase (3CLpro) for coronavirus was identified by comparing the crystal structures of human ......
Inhibitory effects of emodin, baicalin, schizandrin and berberine on hef A gene: Treatment of Helico
AIM: To investigate the inhibitory effects of emodin, baicalin, etc.on the hefA gene of multidrug resistance(MDR) in Hel......
Objective:To characterize the genetic structure of various populations of Culex quinquefasciatus (Cx.quinquefasciatus) f......
Comparative study on occurrence of class A and class Cβ-lactamase genes and their co-occurrence in I
Objective:To determine the occurrence of class A and class Cβ-Iactamase genes and their cooccurrence in Indian Enteroba......
