cyclization相关论文
Direct functionalization of inert C(sp3)-H bonds is a topic of immense contemporary interest and exceptional value in or......
A three-component synthesis of benzo[α]phenanthridines from aromatic aldehydes,cyclohexanones,and aromatic amines has b......
Synthesis of arylsulfonyl-substituted indolo[2,1-a]isoquinolin-6(5H)-one derivatives via a TBAI-cata
We have developed a metal-free radical cascade reaction of N-substituted 2-aryl indoles with read-ily available sulfonyl......
Catalyst-free,direct electrochemical trifluoromethylation/cyclization of N-arylacrylamides using TfN
A new electrochemical strategy for trifluoromethylation/cyclization using TfNHNHBoc as a CF3 source was established.This......
建立了3-氧代-3-芳基丙腈、肼基甲酸甲酯(或水合肼)和芳基磺酰肼的一锅两步反应.在I2和N-碘代丁二酰亚胺(NIS)的作用下,通过环化、......
报道了一种紫外光引发的芳基醛或芳基酮与炔烃的环化反应来构筑茚酮化合物.该反应具有效率较高、原子经济性高、原料简单易得、环......
Catalytic hydrative cyclization of aldehyde-ynamides with water for synthesis of medium-sized lactam
A non-noble metal catalyzed hydrative cyclization of aldehyde-ynamides for efficient and practical synthesis of medium-s......
Kosinostatin (KST) contains an uncommon aminopyrrole moiety,whose biosynthesis has remained elusive.Herein,aminopyrrolin......
An oxidative tandem (4+2)-cyclization/aromatization of N-aryl glycine derivatives with electron-deficient alkenes was fi......
We report an exclusively tandem C—O and C—C bond forming beyond the esterification and cyclization reaction of 2-acylb......
A one-pot three-component method for the synthesis of 2-methyl-3-aminobenzofurans using calcium carbide as a concise sol......
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The synthesis of 4-isochromanones via Parham-type cyclization with Weinreb amide as the internal electrophilic group,t-B......
以二苯基甲烷二异氰酸酯(MDI)和三羟甲基丙烷(TMP)为单体,通过A2+B3方法制备了分子量在2万到12万之间的系列超支化聚氨酯(HBPU)；用......
OG-PP72:The Application of methyl(Z)-2-bromo-4,4,4-trifluoro-2-butenoate:Synthesis of Trifluoromethy
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Tandem Halogenation/Michael-initiated Ring-closing Reaction of α,β-Unsaturated Nitriles and Activate
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SM02-P23:Efficient Synthesis of Pyrrolocoumarins and Furocoumarins by Palladium-Catalyzed Sequential
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Cascade Decarboxylation and Cyclization towards 3-Difluoromethylene-containing Chroman-4-one Derivat
The chroman-4-one scaffold is important structure motif in many natural products,medicinal compounds and biological comp......
The legendary of Sternbach orchestrates an era of benzodiazepine heterocycles in the history of drug development.In the ......
I2/K2CO3-Promoted Ring-opening/Cyclization/Rearrangement/Aromatization Sequence: A Powerful Strategy
Furan derivatives are valuable structural motifs as an important class of five-membered containing oxygen heterocycles i......
Evodiamine is one of the most important components of Evodia rutaecarpa,which has been used for a long time in tradition......
Catalytic Asymmetric Tandem Reaction of Tertiary Enamides: Expeditious Synthesis of Pyrrolo[2,1-a]is
Hexahydropyrrolo[2,1-a]isoquinoline and tetrahydropyrrolo[2,l-a]isoquinolin-3(2H)-one structures occur widely in natural......
Simplification of Rutaecarpine and Luotonin A to tricyclic fused ring and derivatization on ring A f
Rutaecarpine1 and Luotonin A2 are two kinds of natural alkaloids sharing the similar fused quinazolinone structure (Ring......
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OG-OP02:Readily Prepared PhS-or PhSO2-containing Allyl Synthons,Versatile Three-Carbon Annelating Ag
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多聚氮杂环化合物在有机合成、药物化学以及材料化学等领域具有重要的作用.人们已经在多聚氮杂环的修饰和可控转换领域取得了诸多......
报道了Rh(Ⅲ)催化的N-甲氧基-1h-吲哚-1-甲酰胺与亚砜型叶立德的选择性C(2)-H活化/环化反应.该方法为二氢嘧啶并吲哚酮衍生物的制......
Synthesis of 3-Methylthioindoles via Intramolecular Cyclization of 2-Alkynylanilines Mediated by DMS
Main observation and conclusionrnThe intramolecular cyclization of 2-alkynylanilines mediated by DMSO/SOCl2 was found to......
Cu-Catalyzed Cascade Cyclization of Ketoxime Acetates and Alkynals Enabling Synthesis of Acylpyrrole
Main observation and conclusionrnA facile copper-based catalytic system has been developed to enable efficient cyclizati......
Rhodium(Ⅱ)-Catalyzed [4+3] Cyclization of Triazoles with Indole Derivatives and Its Application in t
Main observation and conclusionrnAn efficient rhodium(Ⅱ)-catalyzed [4+3] cyclization reaction of 1-sulfonyl-1,2-3-triaz......
Divergent Synthesis of N-Heterocycles by Merging Borane- Mediated Cyclopropane Ring-Opening and Hydr
Herein,we report the synthesis of N-heterocycles by borane-catalyzed dehydrogenative cyclization of 2-cyclopropyl-N,N-di......
Rhodium-Catalyzed Annulation of Tertiary Aniline N-Oxides to N-AlkylindolesRegioselective C-H Activa
Despite the fact that the direct C-H transformation of various compounds has been established,tertiary anilines rema......
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Carbon dioxide(CO2)is an ideal C1 synthon due to its merits such as abundance,low-toxic,renewable.With the developme......
With a growing concern on greenhouse effect,much attention has been paid to the different issues of CO2....
The ent-kaurane diterpenoids belong to an increasing family of natural products that contain over 1500 members.Most ......
Visible-light-induced Radical Cyclization of Trifluoroacetimidoyl Chlorides with AlkynesCatalytic Sy
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Palladium-catalyzed insertion of f, f-unsaturated N-tosylhydrazones and trapping with carbon nucleop
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Marine-derived actinomycetes are emerging as the most important new sources for novel drug discovery and have produc......
Multiple N-Methylation of Cyclized Melanotropin Backbone Amide Bonds New Insights on Selectivities o
There has been a resurgence of interest in peptide pharmaceuticals recently as they have an advantage of potency,sel......
Access to Polycyclic lndol(en)ines via Base-Catalyzed Intramolecular Dearomatizing 3-Alkenylation of
Polycyclic indolines and indolenines were synthesized via base-catalyzed intramolecular dearomatizing 3-alkenylation rea......
The crude enzyme (PH-1) isolated from Pseudostellaria heterophylla by our group has catalyzed enzymatic cyclization of l......
While studying the electrophilic cyclization of acetylenic malonates in synthesizing malonate indene derivatives with hi......
From readily available propargylic carboxylates, two sequential transformations―gold-catalyzed tandem reactions and Sc(......
The applications of hypervalent iodine(Ⅲ) reagents in the constructions of heterocyclic compounds th
Hypervalent iodine(Ⅲ)reagents have been vastly used in many useful organic transformations.In this review article,we hi......
Synthesis, Crystal Structure, and Antitumor Activity of 1-(4-Methoxybenzylidene)-2-(1-phenyl-6-trifl
The novel title compound 1-(4-methoxybenzylidene)-2-(1-phenyl-6-trifluoromethyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)hydrazi......
