antifungal相关论文
目的 磺胺、磺胺嘧啶和氨苯砜是第一批通过破坏叶酸生物合成过程来治疗疟疾的磺胺类药物,叶酸生物合成过程是寄生虫存活的关键.因......
转化生长因子-β(TGF-β)在许多疾病中过表达,是治疗肿瘤的重要靶点.合成了2个系列3-取代-5-(5-(6-甲基吡啶-2-酰基)-4-(喹啉-6-基......
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Antifungal activities and effect of Lactobacillus casei AST18 on the mycelia morphology and ultrastr
The antifungal effects of Lactobacillus casei AST18 on Penicillium chrysogenum.were investigated.Viable bacteria were us......
Design,synthesis and antifungal activity of Benzofuran derivatives as N-myristoyltransferase inhibit
Benzofuran derivatives(2)have been proved to be antifungal agents targeting fungal N-myristoyltransferase(NMT)with high ......
Coumarins have gained great therapeutic importance in the field of medicinal chemistry due to their extensively biologic......
Chalcones bearing typical diaryl enone backbone are widely present in most natural fruits and vegetables,and have also b......
Benzimidazoles are an important class of nitrogen-containing heterocycles,they display extensively potential application......
Fluconazole is a well known first-line antifungal drug recommended by World Health Organization and is prevalently used ......
A series of Schiff base-appended naphthalimide derivatives were synthesized and characterized by NMR,IR,MS and HRMS spec......
Triazole drugs including Fluconazole,Itraconazole and Voriconazole have been prevalently used in the antiinfective thera......
Infectious diseases caused by microbes are a serious public safety issues associated with significant mortality and heal......
Bacterial resistance continues to progress and pose a significant threat,both in hospitals and,more recently,in the comm......
AIM To report the fungal organisms,clinical features,surgical treatment strategies,and outcomes of patients with culture......
Synthesis,Separation and Antifungal Activity of Diastereoisomers of 2,3,3a,4-tetrahydropyrido[b]thio
The incidence of fungal infections has increased dramatically in recent years.The triazoles antifungal agents which act ......
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Design and Synthesis of Novel Tertiary Amine Azoles and Their Bioactive Evaluation and Relational St
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Synthesis of New Quinolones with Oxiran-2-ylmethyl Moieties at N-1 Position and Their Antifungal Act
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Synthesis and Bioactive Evaluation of Coumarin-derived Bis-azole Alcohols as Novel Fluconazole Analo
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A series of new potentially multi-targeting antimicrobial naphthalimide-derived fluconazole analogs were designed and co......
Synthesis of Benzimidazole-based Phosphonium Salts as Novel Antimicrobial Agents and Their Bioactivi
Organophosphorus compounds are interesting substances with broad biological activities.They have been also developed to ......
Design,Synthesis and Antimicrobial Activities of A Series of Triazole Derivatives as Miconazole Anal
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Tetracyclic tetrahydroprotoberberines (THPB) alkaloids contain an isoquinoline backbone and was endowed with various bio......
Pyrimidines have gained great therapeutic importance in the field of medicinal chemistry due to their extensively biolog......
A series of novel coumarin azoles including imidazoles,triazoles,tetrazoles,thiazoles and so on were designed and synthe......
Synthesis of novel antimicrobial tetrazole compounds and their Supramolecular synergistic effects wi
A series of tetrazole type of antifungal compounds were synthesized and characterized by NMR,IR,MS and HRMS spectra.The ......
Bis-benzimidazoles:Synthesis, Antimicrobial Activities and Supramolecular Interaction with Bovine Se
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Synthesis and Supramolecular Antifungal Behavior of Novel 1,2,4-triazole Quinoline as a New Class of
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The antifungal caspofungin is a semi-synthetic derivative of the lipohexapetide pneumocandin B_0 produced by the fungus ......
Identification of the differentially expressed genes in rice in response to the pathogen Rhizoctonia
Rice sheath blight is an important disease caused by the necrotrophic pathogen Rhizoctonia solani. However,the details o......
Antifungal properties and mechanisms of three volatile aldehydes(octanal,nonanal and decanal)on Aspe
The harmof Aspergillus flavus(A.flavus)and aflatoxin is a severe food safety problemworldwide,which causes huge economic......
<b><span style=“font-family:Verdana;”>Aim: </span></b><span style=“font-family:”“><span style=”font-family:Verdana......
C_(17)-fengycin B,produced by deep-sea-derived Bacillus subtilis,possessing a strong antifungal acti
Root rot disease caused by Fusarium solani is the most devastating disease of the tomato and legume crops in China.The m......
Synthesis, Spectroscopic, Molecular Modeling and Anti-Fungal Studies of Some Divalent Metal Complexe
A novel ligand N-4-hydroxyacetophenone isonicotinoyl hydrazone and its manganese(II) and nickel(II) metal complexes have......
C 17 -fengycin B, produced by deep-sea-derived Bacillus subtilis , possessing a strong antifungal ac
Root rot disease caused by Fusarium solani is the most devastating disease of the tomato and legume crops in China. The ......
A series of natural berberine-derived azoles as potential mulri-targeting antimicrobial agents were designed,synthes......
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Severe Novel Influenza A(H1N1) in Shanghai:Clinical Features, Therapeutic Management and Risk Factor
Objective To analyze the clinical features,therapeutic management and risk factors for mortality of patients with severe......
A series of benzimidazole bearing 2-pyridones 5a-k were synthesized and assessed in vitro for their activity as antimicr......
A series of novel daphneolone analogs was designed and synthesized on the basis of natural product 1,5-diphenyl-2-penten......
Based on the active site of lanosterol 14α-demethylase of azole antifungal agents,sixteen 1-(1H-1,2,4-triazole-1-yl)- 2......
Synthesis and in vitro antitumor activity of 1,3,4-thiadiazole derivatives based on benzisoselenazol
A series of novel 1,3,4-thiadiazole derivatives based on benzisoselenazolone were synthesized and evaluated for their cy......
Design, Synthesis and Antifungal Activity of 6-Fluoro-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]-quinoli
A series of 6-fluoro-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline-2-carboxamide derivatives was designed based on the......
