GUANOSINE相关论文
Development of an eco-friendly and fast HPLC method for quantit-ative analysis of four nucleosides i
An cco-friendly and fast HPLC method was developed for the determination of adenosine,inosine,guanosine and urid-ine in ......
Carcinogenesis is associated with malfunction in the cGMP-mediated regulation of cytosolic Ca<sup>2+</sup> and reactive ......
目的：研究药用蜂蜜中5-羟甲基糠醛（5-hydroxymethyl furfural,5-HMF）的限量检查方法。方法：采用高效液相色谱法,使用C18色谱柱（4.6 mm&#......
STRUCTURAL STUDIES OF RIBONUCLEIC ACIDS Ⅲ. THE STRUCTURES OF SOLUBLE RIBONUCLEIC ACIDS FROM SILK-GLA
<正> In a previous paper, the distribution of nucleotides of H-RNA* and S-RNA isolated from two silk-glands (Bombyx mori......
Nucleotide-specific fluorescence quenching in fluorescently labeled DNA has many applications in biotechnology. We have ......
Insight into the deamination mechanism of 6-cyclopropylamino guanosine analogs for anti-HIV drug des
Deamination is a crucial step in the transformation of 6-cyclopropylamino guanosine prodrug to its active form. A conven......
Melatonin is a circulating hormone that is mainly re- leased from the pineal gland. It is best known as a regulator of s......
人类免疫缺陷病毒(human immunodeficiency virus,HIV)等逆转录病毒可以激活固有免疫反应,但对机体如何识别逆转录病毒却知之甚少......
Determination of urinary 8-hydroxy-2′-deoxyguanosine by capillary electrophoresis with molecularly i
Urinary 8-hydroxy-2’-deoxyguanosine(8-OHdG) is an excellent marker of oxidative DNA damage.In this study,employing guan......
THE ACTION MODE OF CISPLATIN ON DNA-SYNTHESIS AND CHARACTERIZATION OF N_7 N_1 CROSS-LINKAGE MODEL CO
The title Pt-Guo compound was synthesized and isolated by the reaction between cis-[Pt(NH3)2(H2O)2](NO3)2 and guanosine......
Nucleosides were phosphorylated with different N-(O, O-diisopropyl) phosphoryl amino acids to give nucleoside mono phosp......
Glabridin Relaxes Vascular Smooth Muscles by Activating BK_(Ca)Channels and Inhibiting Phosphodieste
Summary: The aim of the current study was to investigate the pharmacological activity of glabridinon the isolated human ......
近年来夜间哮喘引起许多作者的重视。本文概述了夜间哮喘发作的特点和规律,并分别从夜间植物神经功能失调、气道热量、水份丢失、......
Despite major achievements in the treatment ofchronic hepatitis C with the combination ofinterferons and the nucleoside......
AIM: To evaluate whether serum levels of nitric oxide (NO ·) and plasma levels of cyclic guanosine monophosphate (cGMP)......
AIM:To investigate the inhibitory effect of natural taurine(NTau)on portal hypertension(PHT)in rats with experimentally-......
Nitric oxide promotes survival of cerebellar granule neurons cultured in vitro through the Akt pathw
In this study,cerebellar granule neurons were used to examine the role of nitric oxide on cell survival.The N-methyl-D-a......
The laser photochemistry and photosensitization of DNA bases were carried out by using a nanosecond kinetic spectroscopy......
Purines have a recognized importance as intercellular messengers.These molecules play an important role in the developme......
Phosphodiesterase type-5 inhibitor(PDE5-i) drugs were first marketed in 1998(sildenafil) for ’on-demand’ treatment of ......
This paper presents a simple system separat-ing guanosine (G) from cGMP to determine the3’, 5’-cGMP phosphodiesterase......
In this work,the interaction between chelerythrine(CHE)and guanosine is studied using UV-vis and fluorescence measuremen......
Clinical Observation on the Endocrinal and Immune Functions in Subjects with Yin-deficiency Constitu
Objective:To explore the relationship between yin-deficiency constitution(YDC) and biochemical indexes by way of observi......
Cultured Schwann cells were treated with 5.6 mM and 50 mM glucose alternating every 8 hours to simulate intermittent hig......
Synthetic nucleases which rapidly cleave nucleic acids under mild conditions have many important potential applications......
Regulation of intracellular Ca~(2+)and calcineurin by NO/PKG in proliferation of vascular smooth mus
Aim:To determine whether Ca~(2+)/calcineurin mediated the inhibitory effects ofnitric oxide/cGMP-dependent protein kina......
本文用核磁共振 (NMR)波谱和化学定磷法研究了 Ce(SO4) 2 对 5′-腺嘌呤核苷酸 (5′- AMP)及5′-鸟嘌呤核苷酸 (5′- GMP)的水解断......
均匀设计可用作新颖的计量化学和计量合成工具 ,特别是用于有机合成试验设计和优化 从Guanosine分别经酰化和酯解可制务出NAG和TA......
N-4-desmethylwyosine (dYt), a derivative of rare tricyclic nucleosides is probably a new member ofY-nucleosides found in......
The electron transfer reaction of triplet menadione (3MQ?) with polyguanylic acid (polyG) in CH3CN rich (97%) solution w......
The reactions of four different N-(O,O′-diisopropyl) phosphoamino acids (DIPP-aa),such as N-phosphoryl-L-α-alanine (DI......
Neurofibromatosis:The role of guanosine triphosphatase activating proteins in sensory neuron functio
Neurofibromatosis type 1(NF1) is a common autosomal dominant disease characterized by formation of multiple benign and m......
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N~2-(1-Methoxycarbonylethyl)guanosine,a new nucleoside coupled with an amino acid derivative from Am
A new purine nucleoside coupled with an amino acid derivative,N~2-(1-methoxycarbonylethyl)guanosine 1,along withβ-carbo......
Nucleotide-specific fluorescence quenching in fluorescently labeled DNA has many applications in biotechnology. We have ......
Photoelectrocatalytic oxidation of GMP on an ITO electrode modified with clay/[Ru(phen)_2(dC18bpy)]~
An indium tin oxide (ITO) electrode modified with monolayer clay/[Ru(phen)2(dC18bpy)]2+ (phen= 1,10-phenanthroline, dC18......
Changes of nitric oxide synthase and cyclic guanosine mono-phosphate in form deprivation myopia in g
Background The form deprivation(FD)reduces spatial contrasts and induces myopia.Nitric oxide and cyclicguanosine monoph......
AIM:To determine the expression of toll-like receptor 9(TLR9) in pancreatic tumor and the effects of cytosine phosphate-......
本文综述了放射免疫分析对血液病诊断的若干进展。血中β2m6μg/ml 是 MM 选择简单或强烈诱导化疗的分界线。N-HD 和 HD 血清β2m ......
作用模式双嘧达莫(Dipyridamole,潘生丁),抑制细胞再摄取腺苷(强效小冠脉扩张剂),而使内源性腺苷的细胞外水平增加;抑制磷酸二酯......
Objective To develop a rapid high-performance liquid chromatography coupled with diode array detection(HPLC-DAD) method ......
N2-(1-Methoxycarbonylethyl)guanosine, a new nucleoside coupled with an amino acid derivative from Am
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
The interaction between sanguinarine and guanosine was investigated by using UV-vis and fluorescence spectra at pH 7.2. ......
In this work, the interaction between chelerythrine (CHE) and guanosine is studied using UV-vis and fluorescence measure......
以廉价的鸟苷为原料,经过乙酰基保护糖环上的羟基,再和POCl 3反应,将6-位羰基转化为氯原子,继而还原脱除氯原子,然后在亚硝酸异戊......
目的建立毛细管区带电泳法测定红毛五加茎皮中鸟苷含量的方法.方法采用毛细管区带电泳法,以未涂层的熔融毛细管(58 cm×50 μm......
以鸟苷生产菌Ｂａｃｉｌｌｕｓｓｕｂｉｔｉｌｉｓ２０６６为生产菌株，经摇瓶、２０Ｌ自控发酵罐、５００Ｌ发酵罐和２５０００Ｌ生产罐逐级放大试验，分别达到１５．６ｇ／Ｌ，１７．７ｇ／Ｌ，１３ｇ／Ｌ和１１ｇ／Ｌ的产量。......
