guanine相关论文
Fluorescent carbon-based materials have drawn increasing attention in recent years owing to exceptional advantages such ......
Atomic-scale insights into the Interactions between nucleobases and metallic atoms on solid surfaces
Metallic atoms are known to play a vital role in several cellular environments through interacting with uncleobases.As a......
Understanding the reaction mechanism of Guanine(G)in DNA with oxidant radicals is imperative when trying to elucidate th......
Guanine is one of the most widespread organic crystals existing in organisms,which has superior optical properties and e......
An electrochemical biosensor for assessment of the antioxidant activity of antioxidants was fabricated by immobilizi......
The reaction mechanisms of carcinogenic methylating agent iodomethane (MeI) with keto and enol tautomers of thymine (K- ......
Lesch-Nyhan’s综合征(下称LNS)是因嘌呤代谢障碍引起的先天性代谢病。Lesch与Nyhan(1964)首次描述本病的临床特点为智能障碍、舞......
Theoretical characterization of electronic structures and properties of C-F···H-C pseudohydrogen bon
The weak intermolecular interactions between 2-F-tetrahydrofuran and imidazole, pyrimidine, adenine, and guanine were st......
Promising Ultraviolet Absorbers——Novel Guanine Analogs Having Significantly Improved Ultraviolet Abs
Structural properties of nucleobase underlie their ultrafast excited-state dynamics and low fluorescence quantum yields,......
In the present study, a disposable electrochemical DNA nano-biosensor is proposed for the rapid detection of genotoxic c......
Influence of morphine on levels of type Ⅱ inhibitory guanine nucleotide binding protein in primary h
BACKGROUND: The pharmacological action of opioid drugs is related to signal transduction of inhibitory guanine nucleotid......
The Bloom helicase(BLM) gene product encodes a DNA helicase that functions in homologous recombination repair to prevent......
Objective:The aim of our study was to investigate the expression of guanine nucleotide exchange factor Dock180 in ovaria......
The present study examined 58 members of a Kallmann syndrome family and investigated whether there are fibroblast growth......
The adsorption of DNA bases on a magnetic probe composed of Fe atoms and graphene is studied by using firstprinciples ca......
The four nucleic acid DNA bases(adenine, thymine, guanine, cytosine) and ten cis Watson-Crick/Watson-Crick(cis WC/WC) DN......
Bonding mechanism of cis-Pt(NH_3)_2Cl_2 with DNA has been studied by CNDO/2 cal-culation.The computed results of the si......
Molecular analysis of THH-induced mutations at HPRT locus in human promyelocytic leukemia cells with
Objective: To study the genotoxicity and antitumor activity of a Chinese medicinal herb, Triptery-gium Hypoglaucum (Leve......
Analysis of spontaneous, gamma ray-and ethylnitrosourea-induced hprt mutants in HL-60 cells with mul
AIM To explore the molecular spectra and mechanism ofhuman hypoxanthine guanine phosphoribosyl transferase(hprt)gene mut......
Cytokinesis is the last step of the M (mitosis) phase, yet it is crucial for the faithful division of one cell into two.......
据美联社报道人类基因也可以转化成一首首优美的乐章。西班牙马德里数名生物学家最近跟一名法国作曲家合作,将生物的脱氧核糖核酸......
小分子G蛋白Ras超家族成员都是通过与鸟苷酸交换因子(guanine nucleotide exchange factors,GEFs)结合而被活化。GEFs能增加这类小......
Peptide nucleic acid:a new artificial biomacromolecular with great potential applications in molecul
Peptide nucleicacid( PNA) is a DNA mimic thatwas originally developed by Pe-ter E Nielsen in1 991 as a reagentfor sequen......
A new and efficient method for the synthesis of potential antiviral agents Carba-ACV (3)and Carba-DHPG (4) is described......
LPS-induced activation of phospholipase A_2 phospholipase Cand protein kinase C of murine macrophage
A murine macrophage-like cell line,J774,acquried,in response to LPS,an ability to kill tumor necrosisfactor(TNF)-insensi......
The alkylation reaction of guanine and N-acetylguanine with model compounds such as isopropyl bromide or 4-heptyl tosyl......
TERNARY COMPLEXES OF Cu （ATP） AND NUCLEIC ACID BASEADENINE AND GUANINE STABILITY CONSTANTS AND STACK
ＴＥＲＮＡＲＹＣＯＭＰＬＥＸＥＳＯＦＣｕ（ＡＴＰ）ＡＮＤＮＵＣＬＥＩＣＡＣＩＤＢＡＳＥＡＤＥＮＩＮＥＡＮＤＧＵＡＮＩＮＥＳＴＡＢＩＬＩＴＹＣＯＮＳＴＡＮＴＳＡＮＤＳＴＡＣＫＩＮＧＥＦＦＥＣＴ￥ＦｕＨａｉＷＵ；ＸｕｅＹｉＬＥ；ＦｅｎＹｕｎＳＯＮＧ；Ｂｉ...
TERNARYCOMPLEXESOFCu (ATP) ANDNUCLEICACIDBASEADENINE ANDGUANINESTABILITYCONSTANTSANDSTACKINGEFFECT ¥ FuHaiWU; XueY......
Investigation on activating individual living monocytic U937 cell by interleukin-6 using Raman tweez
We investigate the activation of living monocytic U937 cells induced by interleukin-6 (IL-6) at the single cell level. W......
DETERMINATION OF ACYCLOVIR IN PHARMACEUTICAL AND URINE BY HIGH PERFORMANCE CAPILLARY ELECTROPHORESIS
A novel capillary electrophoresis (CE) method for determining acyclovir (ACV) in urine was presented. The separation was......
含大的平面胺配体的二价钯金属配合物在当前的抗肿瘤药物设计中代表着一类具有重要发展前途的先导结构.由于大的平面胺配体具有较......
Several methods including molecular mechanics, molecular dynamics, ONIOM that combines quantum chemistry with molecular......
N-4-desmethylwyosine (dYt), a derivative of rare tricyclic nucleosides is probably a new member ofY-nucleosides found in......
The interaction of cordycepin with calf thymus DNA was investigated at physiological pH with drug/DNA molar ratio of 8.......
Theoretical Investigation of Detailed Thermodynamic Character of Possible Difunctional Adducts Model
The B3LYP/6-31G* level of theory was used to optimize trans-[Pt(NH3)(Am)G-L], where Am = quinoline or thiazole and L is ......
Theoretical Study of Nonclassical Platinum Complexes Bonding to Purine Bases: How the Long-lived Mon
The B3LYP/6-31G* level of theory was used for the optimization of nonclassical platinum drugs with planar aromatic heter......
A new economical synthetic route of entecavir was presented,involving the preparation of the key intermediate 6. The syn......
Geometries and binding energies were predicted at the B3LYP/6-311+G* level for the guanine-BX3 (X = F, Cl) systems and f......
G-quadruplexes comprise a class of secondary structures that are formed in guanine-rich sequences in eukaryotic genomes ......
In the presence of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride(EDC)and N-hydroxysuccinimide(NHS), carbox......
Theoretical Study on the Mechanisms of Action of Sulfurand Nitrogen-containing Amino Acid Residues w
The mechanisms of action on monofunctional guanine adducts of analogues of transplatin with aliphatic amine ligands,such......
The methylation reactions at ten nucleophilic sites in four DNA base molecules with methanediazonium ions(CH3N2+) have b......
To study the efficacy and side effects of antitumor drug by the method of Raman spectroscopy,the cancerous(SGC-7901)and ......
An efficient and novel method for synthesizing 3′,5′-dithio-2′-deoxyguanosine was described.In this method normal gua......
Fabrication and Photoelectrochemical Properties of[Ru(bpy)_2dppz]~(2+) on ITO Electrode Associated w
Electrochemical assembly of[Ru(bpy)_2dppz]~(2+){bpy=2,2’-bipyridine,dppz=dipyrido[3,2-a:2’,3’-c]phenazine} on an ITO ......
Excessive activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) pathways has been linked to......
The strain CCH, isolated from the surface of the plant flower in China, is a wall- less,helical prokaryote which passes......
Irradiation caused DNA single-strand breaks in S180 cells in the presence oflaser-hematoporphyrin derivative(HPD).The n......
