phospho相关论文
AIM: To investigate the expression of genes involved in the gemcitabine-induced cytotoxicity in human pancreatic cancer ......
The risk of hepatocellular carcinoma(HCC) development increases as hepatitis virus C(HCV)-related liver diseases progres......
2,4,6-trinitrobenzene sulfonic acid-induced chronic colitis with fibrosis and modulation of TGF-β1 s
AIM:To investigate whether targeting proteasome might reverse intestinal fibrosis in rats.METHODS:Chronic colitis was in......
Down-regulation of aquaporin3 expression by lipopolysaccharide via p38/c-Jun N-terminal kinase signa
AIM: To investigate the influence of lipopolysaccharide(LPS) through the p38/c-Jun N-terminal kinase(JNK)signalling path......
表皮生长因子信号轴调控细胞可塑性与命运决定等重要细胞生理学过程,但细胞信号转导枢纽蛋白APPL1如何介导表皮生长因子信号轴在细......
Synthesis of biodegradable poly (methylparaben/glycine ethyl ester) phosphazene and further research
Polydichlorophosphazene(PDCP)was synthesized from PCl5 and NH4Cl via a one-pot approach,and then further reacted with gl......
在温和的反应条件下,以1,1,3,3-四甲基胍(TMG)或1,8-二氮杂二环[5.4.0]十一碳-7-烯(DBU)有机碱作为催化剂,催化H-亚磷酸酯与靛红的......
The composites based on the Ti O2 are potentially used in wetland pollution control. In this work, the biological effect......
研究双苯氟嗪对Fas配体分子表达抑制的基因转录机制的影响。通过四血管阻断法建立大鼠全脑缺血再灌注损伤模型,所有实验动物缺血15......
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inh
AIM To examine the effects of Acanthopanax senticosus polysaccharides(ASPS) on intestinal tight junction(TJ) disruption ......
目的:探讨表皮生长因子受体(epidermal growth factor receptor,EGFR)信号通路与卵巢癌顺铂(cisplatin,DDP)耐药细胞株SKOV3/DDP耐......
Phosphorylated heat shock protein 27 is involved in enhanced heart tolerance to ischemia in short-te
Aim:To examine the tolerance of type 1 diabetic hearts to ischemia and reperfusioninjury.Myocardial contents of 27-kDa ......
蛋白激酶B(protein kinase B,PKB)为原癌基因c- Akt的表达产物,是细胞内外磷脂酰肌醇3激酶(phospho- inositide 3 kinase,P13K)信......
蛋白激酶B(protein kinase B,PKB)为原癌基因c- Akt的表达产物,是细胞内外磷脂诜酰醇3激酶(phospho- inositide 3 kinase,P13K)信......
Dissolved nutrient concentration in the Huanghe(Yellow) River at Lijin was monitored during a water-sediment regulation ......
目的 探讨充血性心力衰竭患者甲状腺激素异常变化及临床意义。方法 采用放射免疫法检测了 6 4例充血性心力竭 (CHF)患者及 2 8例......
目的探讨在高糖培养条件下,糖尿病肾病相关微小RNA(MicroRNA,miRNA)即miR-21对小鼠肾小球系膜细胞生长、增殖的影响,及miR-21高表......
OVER-EXPRESSION OF EXTRACELLULAR SIGNAL-REGULATED KINASE IN VASCULAR SMOOTH MUSCLE CELL OF HYPERTENS
Objective To investigate whether extracellular signal-regulated kinase (ERK1/2) was involved in changes of vascular smoo......
AIM: Ursolic acid(UA), a pentacyclic triterpenoid, is used as an anti-inflammatory and anti-cancer agent. There were few......
在动脉粥样硬化的血管重建过程中,血流低切应力是一个重要因素[1]。在低切应力环境下,血管内皮细胞(endothelium cells,ECs)和平滑......
The cardioprotection induced by lipopolysaccharide involves phosphoinositide 3-kinase/Akt and high m
Objective:The mechanisms by which lipopolysaccharide(LPS)pretreatment induces cardioprotection following ischaemia/reper......
Myocardium injury after burn with complicating sepsis about the IL-6 deficiency mice at different ag
Concerning SIRS injury carries a disproportionately high morbidity and mortality in the elderly to re-search whether Int......
Objective To investigate the influence of chronic fluorosis on protein kinase Cβ(PKCβ)p66shc signal pathway in the bra......
Effects of endoplasmic reticulum stressmediated apoptosis in intimal calcification of diabetic apoE~
Objective To investigate the role of endoplasmic reticulum stress(ERS)-mediated apoptosis in athero-scle-rotic calcifica......
Alteration of vascular profilin-1-STAT3 signaling and effects of irbesartan on it in hypertensive mi
AIM:To investigate the alteration of vascular profilin-1-signal transducer and activator of transcription 3(STAT3)signal......
Focal adhesion kinase antisense oligodeoxynucleotides inhibit human pulmonary artery smooth muscle c
Background Pulmonary artery smooth muscle cell (PASMC) proliferation plays an important role in pulmonary vessel struct......
Gab2 plays an important role in FcεRI mediated signal events which lead to degranulation from mast cells. The present s......
A new strategy for the synthesis of unsymmetrical phosphotri-esters was reported: an alcohol was converted to unsymmetr......
Nucleosides were phosphorylated with different N-(O, O-diisopropyl) phosphoryl amino acids to give nucleoside mono phosp......
The syntheses of Keggin and Dawson-structural phospho-tungsto heteropoly compounds and their Peroxo-derivatives(PCWP), ......
PTEN was identified in 1997 as a new tumor suppressor gene on human chromosome 10q23, deletions and mutations of this ge......
For the first time the isomerization of 1, 3, 2-diazaphospholidine-2-selenide derivatives in refluxing benzene in the pr......
Since the epidermal growth factor receptor (EGFR) is a key regulator in cell signaling pathways of cancer cell. To inves......
AIM:To understand the effect of low concentration of N-methyl-N′-nitro-nitrosoguanidine (MNNG),which is a widelydistri......
Objective To investigate the role of extracellular regulated kinase (ERK1/2) pathway in cisplatin-induced apoptosis in h......
SHIP (SH2domaincontaininginositol5′ phosphatase)基因主要在造血细胞表达 ,并在造血细胞的发生发育中发挥关键的负调节作用。......
Saposin C stimulates growth and invasion,activates p42/44 and SAPK/JNK signaling pathways of MAPK an
Aim:To determine the effect of saposin C (a known trophic domain of prosaposin) on proliferation,migration andinvasion,......
目的观察尾吊模拟失重后大鼠比目鱼肌中ERK1/2磷酸化状态的变化。方法采用尾部悬吊大鼠模拟失重效应,以Westernblot技术检测游离的......
Heterojunction bipolar transistor (HBT) is of great interest for the application to microwave power and analog circuits.......
Rare earth luminescent materials have been global green illumination sources today. It was estimated that proportion bet......
Cell surface of aquatic organisms constitutes a primary site for the interaction and a barrier for the nano-TiO_2 biolog......
The effects of nerve regeneration factor (NRF) on neuronal differentiation of PC12 cells and its signaling pathway are i......
Objective: To study the effects of chronic lithium on N-methyl-d-aspartate receptor subunit 2B (NR2B) tyrosine phosphory......
Mechanism of over-activation in direct pathway mediated by dopamine D_1 receptor in rats with levodo
Objective To study the changes of prodynorphin (PDyn) gene expression and dopamine and cAMP-regulated phosphoprotein of ......
Activation of PI3-K/Akt pathway for thermal preconditioning to protect cultured cerebellar granule n
Aim:This study was designed to investigate whether the activation of thephosphatidylinositol 3-kinase(PI3-K)/Akt pathwa......
A new clue for the pathogenesis of hepatitis C virus infection: Activation of the MAPK/ERK signaling
Since cell signal transduction plays an important role in disclosing the nature of human diseases, the pathogenesis of v......
AIM: To study the role of the intracellular receptor domain of gp130 in human inflammatory bowel disease (IBD). METHODS:......
AIM: To investigate in vivo, whether CCK2 receptors (CCK2R) regulate proteins known to play a crucial role in cell proli......
Involvement of P53 and Bax/Bad triggering apoptosis in thioacetamide-induced hepatic epithelial cell
AIM: Thioacetamide (TAA) has been used in studying liver fibrosis and cirrhosis, however, the mechanisms of TAA-induced ......