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CLINICAL APPLICATION OF MONOCLONAL ANTIBODY-DRUG CONJUGATE TO IMMUNOTARGETING CHEMOTHERAPY OF BLADDE
Monocional antibody-drug conjugate was applied in a clinical trial for patients with bladder cancer.Monoclonal antibody ......
Protection of Carassius auratus Gibelio against infection by Aeromonas hydrophila using specific imm
Specific immunoglobulin (IgY) from egg yolk against Aeromonas hydrophila was produced by immunization of White Leghorn h......
Food allergy is a major health issue worldwide. Mast cells play a very important role in the immediate hypersensitivity ......
The growing diffusion of nonalcoholic fatty liver disease(NAFLD) is a consequence of the worldwide increase in the preva......
Treatment regimens for inflammatory bowel disease(IBD) incorporate the use of a variety of immunosuppressive agents that......
The article begins with a brief description of the preparation of monoclonal antibodies against uterine cervical cancer......
Intraperitoneal administration of gonadotropin-releasing hormone-PE40 induces castration in male rat
AIM: To evaluate the long-term effects of gonadotropin- releasing hormone (GnRH)-based vaccine on levels of GnRH antibod......
AIM:To determine whether gypenosides have protective effects in experimental autoimmune optic neuritis(EAON).METHODS:Mic......
Highly Efficient and Economical Baculovirus Expression System for Preparing Human Papillomavirus Typ
To improve the existing human papillomavirus type16 (HPV16) virus-like particle (VLP) preparation, a highly efficien......
Transplantation in children is the best option to treat renal failure. Over the last 25 years the improvements in therap......
AIM:To investigate the role of soluble Fas ligand in autoimmunediseases.METHODS:RT-PCR was performed to amplify sFasL c......
Induction of systemic lupus erythematosus syndrome in BALB/c mice by immunization with active chroma
AIM: To establish an animal model for systemic lupus erythematosus (SLE)-like syndrome in mice. METHODS: BALB/c mice we......
FTY720,Sphingosine 1-Phosphate Receptor Modulator,Ameliorates Experimental Autoimmune Encephalomyeli
FTY720,a sphingosine 1-phosphate receptor modulator,induces a marked decrease in the number of peripheralblood lymphocy......
Recombinant outer membrane protein F-B subunit of LT protein as a prophylactic measure against Pseud
AIM: To study immunogenicity of outer membrane protein F(Opr F) fused with B subunit of LT(LTB), against Pseudomonas aer......
950027 RePOrt of 2 cases of ex扮insie allerg五e alveoli-tis andre讨ew of relevant literature.WANG Guihua(王桂华),et al.P......
Hyperglycemia induces protein nonenzymeatic glycosylation in brain neurons of diabetic rats at early
BACKGROUND: Protein nonenzymatic glycosylation is supposed to be one of mechanisms for chronic complications development......
Objectives The cellular repressor of El A-activated genes (CREG), a novel gene, was recently found to play a role in inh......
Target Organ Protection from a Novel AngiotensinⅡReceptor (AT1) Vaccine ATR12181 in Spontaneously Hy
Hypertension produces pathophysiological changes that are often responsible for the mortality associated with the diseas......
A therapeutic anti-CD4 monoclonal antibody inhibits T cell receptor signal transduction in mouse aut
Background T cell immune abnormalities in patients with dilated cardiomyopathy(DCM)has been intensively studiedover the......
目的在我们先前的研究中发现,鼠疫疫苗免疫的猕猴脾组织中B细胞和T细胞数量明显增加。然而,是否这些细胞是由鼠疫疫苗引起的增殖性......
目的观察并比较日本血吸虫可溶性成虫抗原(SWA)及虫卵抗原(SEA)在诱导CD4+T细胞分化中的不同作用。方法分别用SWA、SEA免疫C57BL/6......
目的:比较我国不同企业研发的肠道病毒71型(EV71)疫苗原液和成品疫苗的小鼠中和抗体应答,为疫苗临床试验提供依据。方法:应用来源......
Synthesis and evaluation of monoclonal antibody against Plasmodium falciparum merozoite surface anti
Objective:To assess the quality of expressed MSP-2 and also to confirm the immune response against different domains of ......
Immunological characterization of recombinant Wuchereria bancrofti cuticular collagen(COL-4)as putat
Objective:To elucidate immunoprophylactic potential of recombinant Wuchereria bancrofti(W.bancrofti)cuticular collagen(C......
Expression of thyroid stimulating hormone β splice variant in thyroid of mouse with autoimmune thyro
Objective To investigate the expression of marrowderived thyroid stimulating hormoneβ(TSHβ)splice variant in thyroid o......
Identification of human cytomegalovirus phosphoprotein 65 in C57BL/6 and BXSB mice as a potential tr
Objective:To investigate the potential role of human cytomegalovirus lower matrix phosphoprotein 65(HCMV-pp65) in murine......
自的 构建了三种表达形大的弓形虫主要表面抗原（ＳＡＧ１）基因－表膜型、分泌型和细胞内型，并分别用于免疫ＢＡＬＢ／Ｃ小鼠、结果ＳＡＧ１基因免疫小鼠后，表膜型和分......
AIM:To prepare and characterize polyclonal antibodiesagainst aldose reductase-like (ARL-1) protein.METHODS:ARL-1 gene w......
AIM:To seek for an effective method to improve the immuneresponses induced by DNA vaccine expressing HBV surfaceantigen......
OBJECTIVES: To construct a DNA vaccine capable of expressing the S gene of hepatitis B virus (HBV)and evaluate the expr......
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Heparin-induced thrombocytopenia in solid organ transplant recipients: The current scientific knowle
Exposure to heparin is associated with a high incidence of immunization against platelet factor 4(PF4)/heparin complexes......
Preparation of monoclonal antibody against apoptosis-associated antigens of hepatoma cells by subtra
AIM:To elucidate the expression of the apoptosis-associatedmolecules in human primary hepatocellular carcinoma(HCC)cell......
CHARACTERIZATION OF MONOCLONAL ANTIBODY CL58 AGAINST CARCINOEMBRYONIC ANTIGEN (CEA) AND STUDY OF ITS
Objective: To study the preparation and characterization of monoclonal antibody (McAb) against carcinoembryonic antigen......
PREPARATION AND IDENTIFICATION OF MONOCLONAL ANTIBODIES AGAINST THE EXTRACELLULAR DOMAIN OF INTEGRIN
Objective: To prepare monoclonal antibody (McAb) against the Integrin a6 extracellular domain and identify its biologica......
PRODUCTION OF PHAGE-DISPLAYED ANTI-IDIOTYPIC ANTIBODY SINGLE CHAIN VARIABLE FRAGMENTS TO MG7 MONOCLO
To generate phage-displayed anti-idiotypic antibody single chain variable fragments (anti - Id ScFv) to MG7 monoclonal a......
Investigation on the effect of peptides mixture from tumor cells inducing anti-tumor specific immune
The peptides mixture was prepared from tumor cells by freezing-thawing cells, precipitation by heating, followed by acid......
Development of an oral DNA vaccine against MG7-Ag of gastric cancer using attenuated salmonella typh
AIM:To develop an oral DNA vaccine against gastric cancerand evaluate its efficacy in mice.METHODS:The genes of the MG7......
Prevention of hepatocellular carcinoma in mice by IL-2 and B7-1 genes co-transfected liver cancer ce
AIM:To study the immunoprotective effect of liver cancervaccine with co-transfected IL-2 and B7-1 genes onhepatocarcino......
Antitumor effects of vaccine consisting of dendritic cells pulsed with tumor RNA from gastric cancer
AIM:To investigate the immunotherapeutic potential ofvaccine consisting of dendritic cells (DCs) pulsed with totalRNA f......
Effects of dendritic cells transfected with full-length wild-type p53 and stimulated by gastric canc
AIM:To investigate the effects of dendritic cells(DCs)transfected with full-length wild-type p53 and stimulatedby gastr......
Purification of heat shock protein 70-associated tumor peptides and their antitumor immunity to hepa
AIM:To purify the heat shock protein(HSP)70-associatedtumor peptides and to observe its non-MHC-I moleculerestrictive a......
Antitumor immunopreventive effect in mice induced by DNA vaccine encoding a fusion protein of α-feto
AIM:To develop a tumor DNA vaccine encoding a fusionprotein of murine AFP and CTLA4,and to study its ability toinduce s......
Construction of human liver cancer vascular endothelium cDNA expression library and screening of the
AIM:To gain tumor endothelium associated antigen genesfrom human liver cancer vascular endothelial cells (HLCVECs)cDNA ......
Production of monoclonal antibody and development of an enzyme-linked immunosorbent assay for the de
An indirect competitive enzyme-linked immunosorbent assay(idc-ELISA) for quantitation of okadaic acid(OA),a marine bioto......
AIM: To develop an oral attenuated Salmonella typhimurium vaccine against gastric cancer and to evaluate its efficacy in......
INTRODUCTIONVascular endothelial growth factor(VEGF)whichis also known as vascular permeability factor(VPF)is a heparin......
Objective: To investigate the influence of consecutive immunization on cellular and humoral immunity in mice. Methods: W......
