streptozotocin相关论文
Jiangtang Xiaozhi Recipe（降糖消脂方） Prevents Diabetic Retinopathy in Streptozotocin-Induced Diabetic Rat
Objective:To evaluate the prevention effect of diabetic retinopathy of Jiangtang Xiaozhi Recipe (降糖消脂方, JXR) in str......
Umbelliferone ameliorates renal function in diabetic nephropathy rats through regulating inflammatio
Diabetic nephropathy (DN) is a leading cause of renal failure,contributing to severe morbidity and mortality in diabetic......
Extracts of passion fruit peel and seed of Passiflora edulis (Passifloraceae) attenuate oxidative st
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Iridoid glycosides are the major component of Corni Fructus.The iridoid glycosides isolated from Corni Fructus(CIG)may a......
The impairment of conditioned response expression in a rodent dementia model induced by streptozotoc
AIM With the finding of insulin receptor in brain areas innervated by cholinergic neurons and some common pathological f......
Rhizoma of Anemarrhena asphodeloides counteracts diabetic ophthalmopathy progression in streptozotoc
Diabetic ophthalmopathy (DO) impairs patients eyesight andeven causes them blind.Here we investigated the effect of 60% ......
Icariside Ⅱ, a novel phosphodiesterase-5 inhibitor, attenuates streptozotocininduced cognitive defic
This study was designed to investigate whether icariside Ⅱ (ICS Ⅱ) could ameliorate spatial learning and memory impair......
Effects of Chinese medicine Tongxinluo on hyperglycemia and beta-cell damage in streptozotocin-induc
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Tangshenping granule inhibits pyroptosis in a rat model of streptozotocin-induced diabetic nephropat
Objective:To explore the inhibitory effect of Tangshenping (TSP) on pyroptosis in a streptozotocin-induced diabetic neph......
Diabetic neuropathy is a disorder which affects various regions of the nervous sys-tem and there is no specific treatmen......
Diabetic neuropathy is a disorder which affects various regions of the nervous sys-tem and there is no specific treatmen......
Objective:To investigate the modulatory effects of bitter gourd extract on the insulin signaling pathway in the liver an......
目的血管内皮生长因子(VEGF)可以导致强烈的血管渗漏。越来越多的文献报道在糖尿病视网膜病变时VEGF升高。早期糖尿病性视网膜病变......
BACKGROUND:Mesenchymal stem cells derived from human umbilical cord blood(UCB-MSCs)have good research and application pr......
Effect of Bu-Zhong-Yi-Qi-Tang on deficiency of N-glycan/nitric oxide and islet damage induced by str
AIM: To investigate the effect of Bu-Zhong-Yi-Qi-Tang (Decoction for Reinforcing Middle Jiao and Replenishing Qi) on def......
BACKGROUND:Activated N-methyl-D-aspartate(NMDA) receptor is involved in the formation of chronic neuropathic pain,and it......
Antioxidant activity of chito-oligosaccharides on pancreatic islet cells in streptozotocin-induced d
AIM:To investigate the antioxidant activity of chitooligosaccharides(COSs)on pancreatic islet cells in diabetic rats ind......
To study the mechanisms of erectile dysfunction (ED) in ex-perimental diabetic (DM) rats, streptozotocin (STZ) was inje......
Juvenile(2-3 years old) cynomolgus monkeys are frequently used as recipients in non-human primate islet transplantation ......
Sapium ellipticum(Hochst) Pax ethanol leaf extract modulates glucokinase and glucose-6-phosphatase a
Objective:To examine the effects of Sapium ellipticum(SE) leaf extract on the hepatic activities of glucokinase and gluc......
糖尿病是由于体内胰岛素绝对或相对不足,从而引起糖、脂肪和蛋白质代谢紊乱的一种常见病和多发病。其病因和发病机理尚不十分清楚......
AIM:To investigate the mechanism behind β-cell regeneration in neonatal rat pancreas treated with streptozotocin (STZ).......
本文就链脲佐菌素(streptozotocin,STZ)诱导大鼠糖尿病模型的几个问题进行了探讨,选用Wistar大鼠,采用尾静脉给药。首先确定了STZ......
Objective:To observe the deregulation of autophagy in diabetic peripheral neuropathy(DPN) and investigate whether Jinmai......
采用链脲佐菌素（streptozotocin，STZ，30mg／kg）给大鼠静脉注射，同时喂高热量食物，建立类似Ⅱ型糖尿病的肥胖糖尿病大鼠模型，以观察黄丹冲剂......
Rosiglitazone prevents gliosis,oxidative/nitrative stress and memory deficits induced by intracerebr
Objective To study the preventive effect of rosiglitazone glial activation,oxidative/nitrative stress and spatial memory......
Ｐｒｏｔｅｃｔｉｖｅｅｆｅｃｔｏｆｔｈｅａｎｇｉｏｔｅｎｓｉｎｃｏｎｖｅｒｔｉｎｇｅｎｚｙｍｅｉｎｈｉｂｉｔｏｒｐｅｒｉｎｄｏｐｒｉｌｏｎｄｉａｂｅｔｉｃｇｌｏｍｅｒｕｌｏｐａｔｈｙｉｎｓｔｒｅｐｔｏｚｏｔｏｃｉｎｉｎｄｕｃｅｄｄｉａｂｅｔｉｃｒ.........
The hypoglycemic activity of an ethanol extract of Hibiscus rosa-sinsnsis was studied in glucose located rats. Afer a s......
IntroductionRenalglomerularlesionofhumanandexperimentaldiabetesmellitusischaracter-izedbyglomerularhypertrophyandexces-s......
Scutellaria barbata attenuates diabetic retinopathy by preventing retinal inflammation and the decre
AIM: To observe the attenuation of ethanol extract of Herba Scutellaria barbata(SE) against diabetic retinopathy(DR) and......
Aim: To study the effect of diabetes mellitus and insulin treatment on rat penile nitric oxide synthase content.Methods......
Troglitazone -induced inhibition of L -type calcium currents is augmented in streptozotocin -induced
Troglitazone -induced inhibition of L -type calcium currents is augmented in streptozotocin -induced diabetic rat cardia......
Effects of Heparin on Transforming Growth Factor-β_1 and Extracellular Matrix Components in the Glom
The effects of heparin on the expression of transforming growth factor-β 1 (TGF-β 1) and two extracellular matri......
Aim: To observe the cavernosal nerve function in male diabetic rats. Methods: Thirty-five male adult SD rats were divide......
CMV-hFasL transgenic mice are sensitive to low doses of streptozotocin-induced type Ⅰ diabetes melli
AIM: To investigate the role of Fas-FasL pathway in the pathogenesis of streptozotocin (STZ)-induced type Ⅰ diabetes m......
有证据表明,活性氧(reactive oxygen species,ROS)参与了胰岛β细胞自身免疫损伤,是自身免疫性糖尿病发病的重要原因之一。一氧化......
Effect of two human growth hormone receptor antagonists on glomerulosclerosis in streptozotocin-indu
AIM: To explore the feasibility of human growth hormone (hGH) receptor antagonist in the treatment of end-stage diabeti......
Aim: To clarify the ultrastructural changes of penile tunica albuginea (TA) in streptozotocin (STZ)-induced diabetic rat......
Adenovirus-mediated CTLA4-FasL gene transfer prevents autoimmune diabetes in mice induced by multipl
Type 1 diabetes is the result of a selective destruction of insulin-producing β cells in pancreatic islets by autoreac......
An increase in opening of BK_(Ca) channels in smooth muscle cells in streptozotocin-induced diabetic
AIM: To investigate the changes of function of large conductance of calcium-activated potassium channels (BKCa channels......
Morroniside protects cultured human umbilical vein endothelial cells from damage by high ambient glu
AIM: To determine whether morroniside, a compound in Cornus officinalis Sieb et Zucc can prevent cultured human umbilic......
AIM: To investigate the efficiency of transfer of A20 gene into pancreas against STZ-induced diabetes. ......
糖尿病并发上消化道动力异常十分常见,但其发病机制尚未完全阐明.Cajal间质细胞广泛分布于胃肠道,有着重要的生理功能,目前认为Caj......
背景:由于胰岛细胞分离技术难度较大,目前糖尿病细胞移植治疗尚缺乏理想的细胞来源。目的:构建具有生理性胰岛素分泌能力胰岛代理......
Glomerular hypertrophy and progressive expansion of extracelluar matrix (ECM) have been regarded as the early feature of......
Aim:To explore the effects and mechanisms of caffeine and coffee on bladderdysfunction in streptozotocin-induced diabet......
Aim:To analyze RhoA expression and activation in the aorta of diabetic rats.Methods:Male SD rats (n=70) were divided in......
