RAC1相关论文
背景:原发性肝癌是我国最常见的恶性肿瘤之一,其发病率在所有恶性肿瘤中排第四位,死亡率排第二位。原发性肝癌分为肝细胞癌、肝内......
目的:本研究试图构建全横断大鼠脊髓损伤模型,探索夹脊电针干预对脊髓损伤大鼠Rac1蛋白表达变化及规律、观察损伤区组织病理形态学......
目的:阐明长链非编码RNA（lncRNA）肺癌相关转录物1（LUCAT1）对非小细胞肺癌（NSCLC）发挥作用的潜在机制。方法:RT-qPCR和Western blot检测基......
研究背景新生儿缺氧缺血性脑病（Hypoxic-ischemic encephalopathy,HIE）是由围生期多种因素（主要原因为窒息）引起的脑血流量减少的一种......
学位
目的:分析耐力与抗阻运动对Nischarin、Rac1蛋白在肾与骨骼肌表达的影响变化,初步探讨影响的可能性机制。方法:将30只健康雄性SD成......
目的:研究SPAG9对膀胱癌细胞侵袭和迁移等生物学行为的影响,进一步探究膀胱癌转移机制,寻找新型治疗膀胱癌的靶点。方法:1、运用实......
[目的]探讨黄芪菟箭合剂（Huangqi Tujian Decoction,HTD）对高糖诱导的肾小球足细胞的 Ras 相关的 C3 肉毒杆菌毒素底物 1（Ras-related......
目的:FAM212B全称（Family with sequence similarity 212,member B）为蛋白序列相似性212成员B家族,同时又叫做INKA2（Inka box actin r......
Hepatic Ischemia-reperfusion Injury in Mice was Alleviated by Rac1 Inhibition – More Than Just ROS-i
Background and Aims: Reducing reactive oxygen species (ROS) production has proven an effective way for allevi-ating oxid......
目的 探讨哮喘患者血清Rac1的表达水平及其与气道炎症的相关性.方法 选取自2020年4月至2021年4月上海交通大学附属新华医院崇明分......
Piperine suppresses growth and migration of human breast cancer cells through attenuation of Rac1 ex
Objective: To investigate the effect of piperine on human breast cancer cells.Methods: The effect of piperine on prolife......
研究背景:高血压病是心血管和脑血管疾病最为重要的危险因素之一[1]。全球高血压病患已超11亿,国内高血压患者数量亦有近3亿,加之......
学习是获得新知识或新技能的神经活动;记忆是信息编码,巩固,存储及提取的神经活动。学习和记忆是相互促进,相互渗透的过程,而非独......
记忆的巩固理论表明,通过神经环路中基于基因调控的突触结构的持续修饰,新获得的不稳定的记忆,逐渐得到巩固和稳定。因此,经过巩固......
目的:通过测定和分析哮喘小鼠肺组织中Rac1酶（Rac1）、白细胞介素-33（IL-33）和II型固有淋巴细胞（ILC2）的水平,观察给予1,25二羟维生素D3（1,......
背景和目的早发性卵巢功能不全（premature ovarian insufficiency,POI）是指女性在40岁以前出现卵巢功能减退,不能产生正常量的雌激素......
背景皮肤作为人体最大的器官,具有重要的屏障保护功能。增殖期是皮肤创伤愈合的重要时期,该时期表皮的再上皮化过程对恢复受损皮肤......
研究背景:肺癌是当前第一大癌症杀手,严重威胁人类健康。肺癌发病隐匿,早期没有症状,易于侵袭和转移,大多数患者初诊时即为中晚期,......
Ras-related C3 botulinum toxin substrate 1 (Rac1),a member of the Rho GTPase family which plays important roles in dendr......
目的:分别探讨IgA肾病（IgAN）患者高尿酸血症（HUA）和新月体形成的相关因素。方法:1.回顾性选取2016年1月至2019年12月在安徽医科大学附......
本研究旨在探讨Fyn调节大脑发育过程神经迁移中的分子机制。通过子宫内胚胎电击转染技术结合免疫荧光染色，观察转染Fyn野型(Fyn-WT)......
目的 研究发现GDP/GTP 结合调控蛋白Rac1 在众多恶性肿瘤细胞中高表达,在肿瘤的发生发展中发挥重要作用。本研究旨在探讨Rac1 对肺......
Objective Breast cancer(BC)is the most common diagnosed malignant tumor and the leading cause of cancer in females world......
Overexpression of CXCL8 Enhances Cell Motility and Promotes Tumor Metastasis in Cervical Adenocarcin
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目的 靶向治疗和免疫疗法是目前肿瘤治疗中最有前景的疗法。然而，对于大多数癌种，化疗仍然是标准的一线治疗方案，在肿瘤治疗中起着至......
TIPE1 induces cell death by negatively regulating Rac-1/Bd2 pathway in hepatocellular carcinoma cell
Background: TIPE1/TNFAIP8L1, Tumor necrosis factor-alpha induced protein 8-like 1, is a newly identified gene belonging ......
Neuronal activity promotes membrane recruitment of Rac1 and dendritic arborization by activating ger
Proper dendritic arborization is essential for establishing normal neuronal circuitry.Here we report a role of geranylge......
Asymmetric meiotic divisions in mammalian oocytes rely on the eccentric positioning of the spindle,resulting in the form......
Involvement of Rac1 signaling pathway in the development of acute inflammatory pain induced by bee v
Objective The Rho GTPase ras-related C3 botulinum toxin substrate 1(Rac1)is a subfamily member of the Rho GTPase family ......
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Astrocyte GGTI-mediated Rac1 prenylation upregulates NF-κB expression and promotes neuronal apoptosi
Stroke is the fifth leading cause of death for Americans,and about 87%of all strokes are ischemic strokes.Astrogliosis p......
Background Secreted frizzled-related protein 1 (sFRP1), Wnt signaling regulator, can positively or negatively regulate t......
RAC1 Confers Cisplatin Resistance in Esophageal Squamous Cell Carcinoma by Modulating the Warburg Ef
Objective Objectives: Esophageal squamous cell carcinoma(ESCC)occurs with high frequency in China and the prognosis is p......
目的：MicroRNAs(miRNAs)在细菌感染过程中对细胞免疫反应的作用逐渐受到重视.然而miRNAs 是如何发挥其调节功能并没有被完全澄清.方......
目的:检测场景恐惧记忆的保持及遗忘与海马Rac1活性的关系,探讨PTSD患者恐惧记忆不能遗忘的分子机制,为其治疗提供新的理论指导.方......
Rac 1 is a small GTPase in Rho family and plays an important role in the cytoskeleton reorganization.It was previously r......
Expression of Rac1 and HIF-1α and VEGF in gastric carcinoma: correlation with angiogenesis and progn
background and aim To investigate the relationship between the expression of hypoxia inducible factor-1α(HIF-1α), Ras-......
目的：探讨Rac1、VEGF蛋白在肝细胞癌组织的表达及其与肿瘤血管形成的关系.方法：应用免疫组织化学法检测Rac1、VEGF在43例肝细胞癌组......
Microglial activation plays an important role in neurodegenerative diseases. Once activated, they have macrophage-like c......
目的探讨皮层肌动蛋白对胶质瘤细胞迁移、侵袭的影响及Rac1在此过程中的作用。方法体外常规培养人胶质瘤U251细胞，免疫荧光染色检测......
Rac1+ cells distributed in accordance with CD 133+ cells in glioblastomas and the elevated invasiven
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目的 观察Rac1基因沉默后对髓母细胞瘤细胞侵袭移动的影响.方法 用逆转录-聚合酶链反应(RT-PCR)和Western blot方法检测Rac1 mRNA......
目的 体外研究外源Rac1基因表达对HT1080纤维肉瘤细胞侵袭胶原蛋白屏障的影响及其机制.方法 将转染显性负调控突变体Rac1V12N17(HN......
目的探讨雌二醇（E2）诱导神经细胞突生长作用及其细胞内分子机制，为激素替代疗法（HRT）预防及延缓女性阿尔茨海默病（AD）患者认知障碍提供科......
Thiopurines are immunomodulators used in the treatment of acute lymphoblastic leukemia and inflammatory bowel diseases.A......
目的探究Rac1在慢性轻度不可预知应激(CUMS)模型大鼠中的作用及其机制。方法采用CUMS大鼠抑郁模型,实时荧光定量聚合酶链反应(RT-P......
