Fibronectin相关论文
第一部分Rig-I通过调控造血干细胞DNA损伤应答维持造血稳态近年来,Rig-I（Retinoid acid inducible gene-I）作为重要的病毒RNA识别受......
研究背景由于国民生活水平不断提高以及生活方式发生改变,在我国,糖尿病已成为继肿瘤、心血管病变之后的第三大威胁人类健康的慢性......
Fibronectin (FN) is a widely existed glycoprotein in human body fluid and plays an important role in the process of woun......
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Purpose ToevaluateanewlowmolecularweightCREKAtargetedcontrastagentCREKA-(Gd-DOTA)4.Itisasmallpeptidethatspecificallybind......
As a contribution to the functionality of nerve guide conduits(NGCs)in nerve tissue engineering,here we report a conduit......
fibronectin upregulation in mesangial cells involves caveolin-1-dependent RhoA-GTP activation via Sr
Background:Increasing evidence indicates that diabetic-mediated renal interstitial fibrosis through extracellular matrix......
Objective: Epididymal protease inhibitor (Eppin) was located on the surface of spermatozoa and modulates the liquefactio......
Earthworm proteases multiply function in protein fibrils degradation involving several diseases incl
Eisenia fetida proteases(EfPs)and Lumbricus rubellus proteases(LrPs)have been used to treat human important diseases inc......
目的：研究丹红注射液对2型糖尿病模型鼠dh/db雄性小鼠由糖尿病引起的视网膜病变和肾病的治疗作用及其相关的作用机制。方法：我们选取......
A novel basic fibroblast growth factor delivery system fabricated with heparin-incorporated fibrin-f
Autologous nerve gratis are widely used in bridging critical gaps of peripheral nerves,but they remain associated with h......
Role of connective growth factor in plasminogen activator inhibitor-1 and fibronectin expression ind
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Dexamethasone enhances invasiveness of Aspergillus fumigatus conidia and fibronectin expression in A
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氰酸盐促进肾小管上皮细胞上皮-间质转化的研究 各种病因导致的慢性肾脏病(Chronic kidney disease, CKD)逐步发展成终末期肾脏......
本文采用单向琼脂扩散法对56例肾脏病患者血浆纤维连接蛋白（Fn）进行了定量检测。结果，正常对照组血浆Fn水平为2．94±0．60g／L，19例急性肾小......
Recent studies suggest that PRL-3 is involved in the metastasis of colorectal cancer, but the mechanism concerning that ......
IGFBPrP1 induces liver fibrosis by inducing hepatic stellate cell activation and hepatocyte apoptosi
AIM:To investigate the role and mechanism of insulinlike growth factor binding protein-related protein 1(IGFBPrP1)in the......
Objective To investigate the association between β3 integrin-fibronectin signaling and salpingitis. Methods Thirteen ch......
输精管结扎后输精管吻合术已是一种恢复生育的有效方法,但输精管结扎后产生的抗精子抗体可引起精子自动凝集及制动,对于抗体是否......
Induction of matrix metalloproteinase-9 and-2 activity in mouse blastocyst by fibronectin-integrin i
Fibronectin, a major extracellular matrix, plays an important role in embryo implantation by mediating embryo adhesion a......
纤维连接蛋白(fibronectin Fn)主要分布于肾小球系膜。但在IgA肾病(IgAN)肾小球内,Fn的分布可变化为系膜型和毛细血管型两种,这种......
人妊娠５－８周的胎盘绒毛经匀浆后，用２ｍｏｌ／Ｌ ｕｒｅａ－ＰＢＳ提取，通过Ｈｅｐａｒｉｎ－Ｓｅｐｈａｒｏｓｅ ４Ｂ亲和柱层析，再经Ｓｅｐｈａｒｏｓｅ ＣＬ－６Ｂ凝胶过滤层析，得到人早期胎盘纤维连接蛋白（ｅａｒｌｙ ｐｌａｃｅｎｔａ ｆｉｂ－ｂｒｏｎｅｃｔｉｎ，ｅｐＦＮ）。经还原及非还原ＳＤＳ－ＰＡＧＥ和免疫......
人血浆纤连蛋白（Ｆｉｂｒｏｎｅｃｔｉｎ，Ｆｎ）与人胎盘纤连蛋白两者在肽链结构上基本相同，但人血浆Ｆｎ的Ｎ－糖链结构为二天线结构，而人胎盘Ｆｎ不仅Ｎ－糖链的数量增加，同时还含有......
饰胶蛋白聚糖 (decorin ,DCN)是一种富含亮氨酸的小分子蛋白聚糖 (SLRPs) ,普遍存在于ECM中。DCN能调节胶原合成 ;能与fibronectin......
转化生长因子β(TGFβ)是巨噬细胞、单核细胞和纤维母细胞强有力趋化剂,可刺激纤维母细胞合成胶原和纤维结合素(fibronectin),抑......
胎儿纤连蛋白(fetal fibronectin,FFN)是一种位于绒毛滋养层细胞外间质的多肽。为观察FFN在胎盘附着蜕膜中所起的作用,测定了重度......
过期妊娠使围产儿死亡率及孕严妇患病率均升高,目前关于其处理尚有争议,人们都期望拥有一种检测方法以预测是否会发生过期妊娠,从......
极低体重儿(VLBW,...
据文献记载,血纤粘连蛋白(fibronectin,FN)参与儿童糖尿病(DM)微血管病变。作者对年龄7～16岁的糖尿病患儿111例血FN动态变化作了调......
纤维连结蛋白(fibronectin,Fn)是血浆与细胞表面的一种多功能前β糖蛋白。有促进吞噬的作用,与细胞粘附、迁移和趋化有关。参与对......
研究目的是为了评价在足月产成功引产预测中生物化学(胎儿fibronectin测定)或生物物理(阴道超声宫颈评价)试验比指诊更有价值。 ......
INTRODUCTIONSince１９８０＇s，increasingexperimentalandclinicalevidencehassuggestedthatlipidsareimportantmodula－torsinprogressivekidn......
糖尿病肾病 (diabeticnephropathy ,DN)是糖尿病最为严重的慢性并发症之一 ,是导致终末期肾脏疾病最常见的原因 ,其基本病理特征包......
Glomerular hypertrophy and progressive expansion of extracelluar matrix (ECM) have been regarded as the early feature of......
Synergistic Effects of Activin A and Fibroblast Growth Factor 2 in the Modulation of Insulin Express
Diabetes is the most prevalent and serious metabolic disease, and the number of diabetic patients worldwide is increasin......
目的:初步研究阿霉素导致血管壁脂质过氧化状态下纤连蛋白(fibronectin,FN)及P105基因表达的变化及其意义,并对动脉粥样硬化患者的......
Effective suppression of fibronectin synthesis by retrovirus delivered shRNA in rat cardiac fibrobla
Extracellular matrix overexpression is a common final pathway that leads to ven-tricular remodeling. Fibronectin plays a......
探讨吲哚胺2,3-双加氧酶(IDO)通过细胞外黏附分子整合素对子宫内膜间质细胞(ESC)与细胞外基质黏附能力的调控。收集非内异症患者健......
Adiponectin levels are associated with the number and activity of circulating endothelial progenitor
Objective:To study the relationship between plasma adiponectin concentration and the functional activities of circulatin......
针对瓜氨酸化蛋白的抗体被认为是诱发类风湿性关节炎(rheumatoid arthritis,RA)的元凶,本研究旨在探讨瓜氨酸化纤维连接蛋白(citru......
Asiatic acid mitigates hyperglycemia and reduces islet fibrosis in Goto-Kakizaki rat,a spontaneous t
The Goto-Kakizaki(GK) rat is a spontaneous type 2 diabetic animal model,which is characterized by a progressive loss of ......
Enhanced Angiotensin-Converting Enzyme 2 Attenuates AngiotensinⅡ-Mediated Hypertension,Myocardial Fi
Background Activation of the renin-angiotensin system and the subsequent generation of angiotensin(Ang)Ⅱis an important......
Effect of HIF1α-KIM1 pathway on extracellular matrix degradation in human tubular epithelial cells u
Objective To investigate the effect of hypoxia inducible factor 1α(HIF1α)-kidney injury molecule 1(KIM1)pathway on ext......
Effect of high glucose on the Notch signal pathway in mesangial cells and intervention of the cordyc
Objective To investigate the expression of Notch signaling molecules,transforming growth factor-β(TGF-β)and fibronecti......
The Expression and Change of the β_3 Integrin Subunit and Fibronectin in Normal Human Oviductal Tiss
Objective To investigate the expression and change of the β3 integrin subunit and fibronectin in normal human oviducta......
The purpose of the present study was to study the impacts of eplerenone(EPL), an antagonist of mineralocorticoid recepto......
Tenascin C upregulates interleukin-6 expression in human cardiac myofibroblasts via toll-like recept
AIM:To investigate the effect of Tenascin C(TNC)on the expression of pro-inflammatory cytokines and matrixmetalloprotein......
