glycosylation相关论文
糖基化是蛋白质翻译后修饰的重要形式之一，糖蛋白的糖链在细胞识别、细胞间信号传递、细胞迁移、增殖及分化中均具有重要作用，唾液酸......
目的:建立检测唾液酸化胎球蛋白A（Sia-fetuin A）的凝集素-酶联免疫吸附试验方法（lectin-ELISA），探讨其在原发性肝细胞癌（HCC）中的诊断价值......
糖基化修饰是免疫球蛋白G（IgG）结构和功能的一部分，唾液酸位于IgG N-糖链的最末端，通过调节IgG与可结晶片段γ受体及补体的结合而调控I......
血小板表面具有丰富的糖萼，血小板糖基化在生理止血机制中发挥重要作用，调节血小板与受体蛋白相互作用，并通过自身糖代谢系统动态重塑......
A convenient and highly efficient strategy was developed for the simplification of enzymatic synthesis and purification ......
2-Diphenylphosphinoyl-acetyl as a Remote Directing Group for the Highly Stereoselective Synthesis of
The configuration of the anomeric glycosidic linkages is crucial for maintaining the biological functions and activities......
A green and efficient photolabile protecting group (PPG)-mediated glycosidation approach for the synthesis of 2-deoxy-gl......
Silencing of ER-resident oxidoreductase PDIA3 inhibits malignant biological behaviors of multidrug-r
Glycosylation is a common posttranslational modification of proteins,which plays a role in the malignant transformation,......
Amicetin and congeners constitute a small family of complex pyrimidine nucleosides,which exhibit strong antibiotic activ......
The present study was designed to perform structural modifications of of neobavaisoflavone (NBIF),using an in vitro enzy......
Unfolded protein response (UPR) is an adaptive reaction for cells to reduce endoplasmic reticulum (ER) stress.In many ty......
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Carbohydrate modified gold nanoparticles are very useful tools and reagents in the study of proteomics and glycomics(1,2......
Hemocyanin(HMC) is an important multifunctional non-specific immune molecule.In this study,we purified two HMCs from Lit......
A lectin-based glycomic approach identifies FUT8 as a driver of radioresistance in esophageal cancer
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Glycosylation is one of the most common protein post-translational modifications and plays an important role in protein ......
Baicalin is the most abundant ingredient of Scutellaria baicalensis,which has been shown to have a variety of biological......
Role of asparagine at position 562 in dimerization and immunogenicity of the hepatitis E virus capsi
Background:The hepatitis E virus(HEV)capsid protein,pORF2,contains 2 potential N-glycosylation sites,N137 and N310,locat......
Histidine-rich glycoprotein function in hepatocellular carcinoma depends on its N-glycosylation stat
Hepatocellular carcinoma (HCC) is the third most common cause of cancer mortality.Significantly downregulated histidine-......
Chamaelirium luteum(L.)A.Gray,commonly known as “false unicorn” or “helonias”,belongs to the family Melanthiaceae th......
We have recently prepared O-and S-glycosyl aryl boronic acids,which are proved as viable material for further applicatio......
Hemocyanin(HMC) is an important multifunctional non-specific immune molecule.In this study,we purified two HMCs from Lit......
Comparative Analysis of Membrane Proteome of among wild Aspergillus Fumigatus and its pmt1, pmt2 mut
At first,we optimized separation protocol of membrane proteins of Aspergillus fumigates by 2D Fluorescence difference ge......
Enrichment of GalNAz labled-glycoproteins by Novel Disulfideand Terminal Alkyne-modified Magnetic Be
Glycosylation is one of the most significant and widespread posttranslational modification of proteins.The change of gly......
Our Recent Progress on New Glycosylation Methods and New Glycosylated Nanodevices Interfacing with L
The diverse presence as well as their very specific bio-responses of glycoconjugates found in all living species require......
Cell-based QCM biosensors for Real-time Determination of Binding Kinetics of Lectin-carbohydrate Int
A novel approach based on cell biosensor to studying the lectin-carbohydrate interactions on the surface of cancer cells......
Osteopontin (OPN) is a multifunctional phosphorylated glycoprotein and it is involved in a broad range of functions in b......
High Efficiency Characterization of Protein Glycosylation by Combining Glycosite and Site-specific G
the glycosites and site-specific glycoforms of human liver tissues between HCC and adjacent normal tissues were well cha......
Quantitative analysis of therapeutic mAb glycoforms by hydrophilic interaction chromatography enrich
Monoclonal antibodies(mAbs),areone of the most important protein drugs have attracted increasing attention.However,the p......
Development of Lectin Affinity Based Enrichment of Glycopeptides Combined with Flow Field-Flow Fract
Glycosylation of protein plays a crucial role in many physiological functions and biological pathways.An incorrect glyco......
Glycomic analysis of Recombinant Erythropoietin Biotherapeutics by Capillary Electrophoresis and Ult
Glycosylation impact the pharmacokinetics,pharmacodynamics and/or efficacy of glycoprotein therapeutics1.Erythropoietin(......
Glycoproteogenomics:Setting the Course for Next-generation Cancer Neoantigen Discovery for Cancer Va
Molecular-assisted precision oncology gained tremendous ground with high-throughput next-generation sequencing (NGS), su......
BACKGROUND The ATP6AP1 gene coding for the accessory protein Ac45 of the vacuolar-type adenosine triphosphatases(V-ATPas......
Many cancer cells in solid tumors are hypoxic or pseudohypoxic and create acidic environment for malignancy progression.......
Objective: Obesity is becoming a worldwide health problem that increases the risk of somatic and psychosocial compli......
Endogenous glycopeptidome in serum was rarely reported due to the low abundance and insufficient enrichment of endog......
AE-PP50One-pipeline Approach for Glycoprotein, Glycosite and Corresponding Glycan Analysis by Tandem
A novel one-pipeline workflow was reported, which can realize glycoprotein identification and obtain intact glycosyl......
N-Acetylgalactosaminyltransferase-14(GALNT14)is the member of acetylgalactosaminyl transferases family1.In our previ......
Novel N-linked Trisaccharide Decorates the S-layer Glycoproteins from the Halophilic Archaeon Haloar
Glycosylation is the most abundant and complex protein modifications in nature.First demonstrated in 1938 by Neuberger, ......
糖基化是蛋白质生物合成过程中最重要的翻译后修饰之一，免疫球蛋白糖基化可通过调节抗体稳定性和影响其与不同FcγRs的相互作用，发挥......
Esophagus squamous cell carcinoma(ESCC) is one of the most aggressive malignant tumors in the world. Our previous data d......
Although prohibitin 1(PHB) is known to be associated with tumors,there are few studies regarding the role of PHB in hepa......
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The tremendous functional,spatial,and temporal diversity of the plant proteome is regulated by multiple factors that con......
目的 通过观察2型糖尿病患者血清β-淀粉样蛋白(Aβ) 1-42、可溶性糖基化终末产物受体(sRAGE)水平变化,探讨2型糖尿病患者认知功能......
Influences of AMY1 gene copy number and protein expression on salivary alpha-amylase activity before
OBjECTIVE:To compare the correlations between salivary alpha-amylase(sAA) activity and amylase,alpha 1(salivary) gene(AM......
