stellate相关论文
Naringenin prevented nonalcoholic steatohepatitis fibrosis via regulating MAPK/FoxO3a pathway and pr
OBJECTIVE The pathological characteristics of nonalcoholic steatohepatitis(NASH)include liver steatosis,inflammation,and......
β-Arrestin2 deficiency attenuates oxidative stress in mouse hepatic fibrosis through modulation of N
Hepatic fibrosis is a disease characterized by excessive deposition of extracellular matrix (ECM) in the liver. Activati......
Effects of Guangxi Hepu Pearl Hydrolysate on Proliferation Activity and Apoptosis of Human Hepatic S
[Objective] The paper was to observe the effects of Guangxi Hepu pearl hydrolysate on proliferation and apoptosis of hum......
IGFBPrP1 induces liver fibrosis by inducing hepatic stellate cell activation and hepatocyte apoptosi
AIM:To investigate the role and mechanism of insulinlike growth factor binding protein-related protein 1(IGFBPrP1)in the......
AIM:To explore the effect of sophocarpine on experimental liver fibrosis and the potential mechanism involved.METHODS:So......
There have been considerable recent advances towards a better understanding of the complex cellular and molecular networ......
Liver cirrhosis is the final pathological result of various chronic liver diseases,and fibrosis is the precursor of cirr......
目的探讨硫化氢(H2S)在p38MAPK信号通路对大鼠肝星状细胞(hepatic stellate cell,HSC)凋亡中的作用及磷酸化P38、Caspase-3蛋白表......
Platelets contain bio-physiological substances, including insulin-like growth factor-1, vascular endothelial growth fact......
Recent data indicate that hepatic angiogenesis, regardless of the etiology, takes place in chronic liver diseases(CLDs) ......
AIM: To investigate the hepatoprotective effects and antioxidant activity of caffeic acid phenethyl ester(CAPE) in rats ......
Matrix metalloproteinases(MMPs) are a family ofproteases using zinc-dependent catalysis to break down extracellular matr......
Excessive alcohol intake may induce hepatic apoptosis, steatosis, fibrosis, cirrhosis and even cancer. Ethanolinduced ac......
Non-alcoholic fatty liver disease(NAFLD)is a major cause of liver disease around the world.It includes a spectrum of con......
AIM: To investigate the effects of activated rat hepatic stellate cells(HSCs) on rat Th1/Th2 profile in vitro.METHODS: G......
Mi R-9a-5p regulates proliferation and migration of hepatic stellate cells under pressure through in
AIM:To reveal the functions of micro RNAs(mi RNAs) with respect to hepatic stellate cells(HSCs) in response to portal hy......
Effect of stellate block on vasomotor factor, vascular endothelial nitricoxide synthase and pulmonar
BACKGROUND: At present, inhalation of nitrogen monoxidum (NO) or other angiotenic is widely used to cure hypoxic pulmona......
目的:肝星状细胞(hepatic stellate cell,HSC)激活并发生表型改变是肝纤维化形成的关键,本实验期待通过构建慢病毒rno-miR-126,并......
Endoglin, also known as cluster of differentiation CD105, was originally identified 25 years ago as a novel marker of en......
Impaired balance of T helper 17/T regulatory cells in carbon tetrachloride-induced liver fibrosis in
AIM:To investigate the effect of T helper(Th)17/T regulatory(Treg)cells on hepatic fibrosis in mice and its possible mec......
Neoglycoproteins of human serum albumin (HSA) modifiedwith some kind of carbohydrates were synthesized. Theirmolecular ......
Between 30% and 67% of gastrointestinal carcinoid tumours are invasivewhen discovered (Balthazar, 1978). Most (75%) of ......
Interleukin-1 beta up-regulates tissue inhibitor of matrix metalloproteinase-1 mRNA and phosphorylat
AIM: To study the relationship between interleu-kin-1beta (IL-1β) up-regulating tissue inhibitor of matrix metalloprote......
Effects of endothelin-1 on hepatic stellate cell proliferation,collagen synthesis and secretion,intr
AIM:To explore the effects of endothelin-1(ET-1) onhepatic stellate cells (HSCs) DNA uptake,DNA synthesis,collagen synt......
AIM: To evaluate the effect of resistance to activated protein C (aPCR), the most common known inherited thrombophilic d......
Transplantation of fetal liver epithelial progenitor cells ameliorates experimental liver fibrosis i
AIM: To investigate the effect of transplanted fetal liver epithelial progenitor (FLEP) cells on liver fi brosis in mice......
AIM:To develop the effective technology for reconstruc-tion of a liver organ in vitro using a bio-artificial liver.METH......
Effect of hepatic iron concentration reduction on hepatic fibrosis and damage in rats with cholestat
AIM: To assess the effect of iron reduction after phlebotomy in rats with “normal” hepatic iron concentration (HIC) on......
Effects of interleukin-10 on activation and apoptosis of hepatic stellate cells in fibrotic rat live
AIM:To study the effects of interleukin-10(IL-10)on the expression of α-smooth muscle actin(α-SMA),nuclear factor-κB......
AIM:The GFAP was traditionally considered to be abiomarker for neural gila(mainly astrocytes and non-myelinating Schwan......
Interleukin-22 ameliorates liver fibrogenesis by attenuating hepatic stellate cell activation and do
AIM:To investigate the effect of interleukin(IL)-22 onhepatic fibrosis in mice and the possible mechanism involved.METHO......
Progressive liver fibrosis is a major health issue for which no effective treatment is available,leading to cirrhosis an......
ＩＮＴＲＯＤＵＣＴＩＯＮＬｉｖｅｒｆｉｂｒｏｓｉｓｉｓｔｈｅｃｏｍｍｏｎｐａｔｈｏｌｏｇｉｃａｌｆｅａｔｕｒｅｏｆｃｈｒｏｎｉｃｌｉｖｅｒｄｉｓｅａｓｅｓ，ａｎｄｉｓｃｌｏｓｅｌｙａｓｏｃｉａｔｅｄｗｉｔｈｃｈａｎｇｅｓｏｆｌｉｖｅｒｃｅｌｆｕｎｃｔ...
INTRODUCTIONLiverfibrosisisthemonmonpathologicalfeatureofchronicliverdiseases, andiscloselyasociatedwithchangesofli......
ORIGlNALARTlCLEDynamicchangesoftype1,IIIandlVcollagensynthesisanddistributionofc0llagen-producingcellsincarbontetrachlor......
Dynamic changes of type Ⅰ,Ⅲ and N collagen synthesis and distribution of collagen-producing cells in
AIM To find out the relationship between the gene transcription of different types ofprocollagen and the deposition of ......
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 expression in fibrotic rat li
INTRODUCTIONLiver fibrosis is an excessive deposition ofextracellular matrix(ECM)resulted from bothincreased synthesis ......
Effect of anti-fibrosis compound on collagen expression of hepatic cells in experimental liver fibro
INTRODUCTIONLiver fibrosis is mainly characterized by theexcessive synthesis and decreased degradation ofextracellular ......
Effects of retinoic acid on proliferation,phenotype and expression of cyclin-dependent kinase inhibi
AIM To study the molecular mechanisms ofretinoic acid(RA)on proliferation andexpression of cyclin-dependent kinase inhi......
AIM To investigate effect of losartan,an AT1receptor antagonist,on hepatic fibrosis induced byCCl_;and to determine whe......
Objective To investigate the role of fibronectin(FN) receptor α 5β 1 in liver fibrosis Methods Northern blot ana......
纤维化是慢性肝病的基本病理特征,也是进一步向肝硬化发展的主要中间环节。目前,抗纤维化药物虽不少,但作用多不确切。肝星状细胞(......
肝纤维化的形成是一缓慢而复杂的过程 ,不论何种致病因素 ,其机制都是肝脏受到外界刺激后引起细胞因子的释放 ,细胞因子 -细胞 -细......
INTRODUCTIONPlasminogen activator inhibitor type 1(PAI-1),anapproximately Mr 50000 glycoprotein,is the majorphysiologic......
Effects of hypoxia,hyperoxia on the regulation of expression and activity of matrix metalloproteinas
AIM To study the effects of hypoxia,hyperoxia on theregulation of expression and activity of matrixmetalloproteinase-2 ......
AIM To examine the expression of activin A, amember of the transforming growth factor (TGF-β) superfamily, recently ha......
Objective The present study was designed to examine whether the renin-angiotensin system would be implicated in the deve......
Liver fibrosis is a dynamic course leading tocirrhosis from a various chronic liver diseases. Thepathological basis of ......
Liver fibrosis or cirrhosis is a common progressivelypathological lesion of chronic liver diseases inresponse to variou......
近年来,肝星状细胞在肝纤维化过程中的作用得到广泛重视。本文综述了国外肝星状细胞凋亡的研究进展,分别对肝星状细胞凋亡的活化机......
AIM:To explore the role of focal adhesion kinase(FAK)in the apoptosis in culture-activated rat hepatic stellatecells(HS......
