CHEMORESISTANCE相关论文
Objective:To evaluate the effect of Pien Tze Huang (片仔癀,PZH) on breast cancer chemoresistance and related epithelial-......
The Zuo Jin Wan Formula increases chemosensitivity of human primary gastric cancer cells by AKT medi
Resistance to cisplatin (DDP)-based chemotherapy is a major cause of treatment failure in human gastric cancer (GC).It i......
One of the factors promoting tumoral progress is the abnormal activation of the epithelial-mesenchymal transition (EMT) ......
miR-33aisup-regulatedinchemoresistantosteosarcomaandpromotesosteosarcomacellresistanceto
目的：筛选骨肉瘤化疗耐药患者中差异表达的miRNAs,重点确定调控TWIST表达和骨肉瘤化疗耐药的miRNA.方法：1.miRNA芯片筛选骨肉瘤化疗......
Chemotherapy increased PD-L1 expression protects cancer cells by inducing chemoresistance and lympho
Purpose: Immune escaping and chemoresistance of tumor cells constitute two major key barriers to the successful manageme......
The effect of DNA-PKcs on chemoresistance to cisplatin and P-gp expression in CD133+ osteosarcoma MG
Purpose 1.To investigate the effect of DNA-PKcs on chemoresistance to cisplatin(CDDP)in cancer stem cells(CSCs)of osteos......
Identification of FABP5 involved in primary chemoresistance of ES-small cell lung cancer by Label-fr
Objective Small cell lung cancer(SCLC),a refractory malignant tumor of neuroendocrine origin,accounts for approximately ......
Rac1 enhances non-oxidative pentose phosphate pathway to induce chemoresistance of breast cancer via
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Colorectal cancer cell-derived CCL20 recruits regulatory T cells to promote chemoresistance via FOXO
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Objective Malignant solid tumors usually rely on aerobic glycolysis to generate ATP,including CRC....
The sensitization and mechanisms of halofuginone in epirubicin resistance of basal like breast cance
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The MRVI1-AS1/ATF3 signaling loop sensitizes nasopharyngeal cancer cells to paclitaxel by regulating
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Autophagy has been recognized as an important element of tumor cell migration, invasion, and chemoresistance, and ourpre......
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Objective Drug resistance remains one of the major reasons of therapy failure in cancer patients.Although the mechanisms......
PCDHGB7 increases chemosensitivity to carboplatin by inhibiting HSPA9 via inducing apoptosis in brea
Objective Breast cancer is one of the most serious cancers worldwide,and chemotherapy resistance frequently drives cance......
Objective As tumor morbidity and mortality have risen year by year,cancer has become Chinas leading cause of death,with ......
LncRNA SNHG6 promotes chemoresistance through ULK1-induced autophagy by sponging miR-26a-5p in color
Objective Objectives: Chemotherapy resistance is one of the main causes of recurrence in colorectal cancer patients and ......
Objective Glioma is the most malignant central nervous tumor with poor clinical outcomes.The development of resistance a......
Objective As the most lethal gynecologic cancer,ovarian cancer threatens womens health severely.Chemoresistance,especial......
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Paracrine HGF/c-met axis mediates the effects of PSC on gemcitabine chemoresistance via promoting EM
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Metronomic chemotherapy remodel cancer-associated fibroblasts to decrease chemoresistance of gastric
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Objective: Acquiredresistance to standard chemotherapy causes treatment failure in patients with advanced non-small lung......
Metabolic enzyme PDK3 forms a positive feedback loop with transcription factor HSF1 to drive chemore
Objective Dysregulation of metabolism plays an important role in the development and progression of cancers,while the un......
Objective Object: Chemoresistance remains the uppermost disincentive for cancer treatment on account of many genetic and......
High expression of UBD correlates with epirubicin resistance and indicates poor prognosis in triple-
Objective: Triple-negative breast cancer (TNBC) is a heterogeneous subtype of breast cancer that is prone to recurrence ......
Evaluation of characteristic of CD117+CD44+ovarian cancer stem cells in three dimensional basement m
Background: Cancer stem cells (CSCs) are thought to be able to survive conventional chemotherapeutic treatments because ......
TMZ(temozolomide)treatment,as first-line chemotherapy in GBM(glioblastma),faced with drug resistance.Recent studies emph......
Testicular orphan nuclear receptor 4-associated protein (TRA16) is functionally correlated with stem
目的： We previously found that TRA16, testicular orphan nuclear receptor-4 (TR4)-associated protein,suppressed the TR4-me......
Cancer cell membrance-functionalized oxygen-nanocarrier With doxorubicin for breaking hypoxia-induce
The rapid growth of cancer cells as well as the distorted blood vessels cause low oxygen content in solid tumors....
LASS2 enhances the chemosensitivity of bladder cancer by inhibiting endoplasmic reticulum pathway-me
目的 The purpose of the present study was to elucidate the relationships among LASS2,autophagy and bladder cancer chemos......
Paracrine HGF/c-met axis mediates the effects of PSC on gemcitabine chemoresistance via promoting EM
Objective The biological behaviors of pancreatic ductal adenocarcinoma are complicated mainly due to heterogeneity of pr......
Objective: As one of the major cancers with a high mortality rate, lung cancer is still a huge health challenge worldwid......
PD-L1 Promotes Tumor Progression, Chemotherapy Resistance, and Poor Clinical Outcomes in Non-Small C
Objective: Although neoadjuvant chemotherapy (NAC) for advanced lung cancer can improve operability and local disease co......
3-O-(Z)-coumaroyloleanolic acid overcomes Cks1b-induced chemoresistance in lung cancer by inhibiting
OBJECTIVE To investigate 3-0-(Z)-coumaroyloleanolic acid (3-COA), an active ingredient of oleanolic acid in the TAIWANG ......
A Novel Recombinant hyaluronidase PH20-Fc Targets Tumor Architecture to Favor Drug Penetration for S
The tumour microenvironment, which is conventionally characterized by increased interstitial fluid pressure (IFP), lowed......
Oncogenic Retinoic Acid Receptor γ Knockdown Reverses Multi-Drug Resistance of Human Colorectal Canc
Retinoic acid receptor γ (RARγ), a unique member of the nuclear receptor superfamily, plays an important role in the p......
The DNA methylation-regulated miR-193a-3p dictates the multi-chemoresistance of human osteosarcoma c
Chemoresistance hinders the curative cancer chemotherapy.MicroRNAs(miRNAs)have been identified as key players in the che......
Hedgehog Signaling Pathway Affects the Sensitivity of Hepatocellular Carcinoma to Drug Therapy throu
Background: A major challenge of chemotherapy in hepatocellular carcinoma(HCC)is to overcome intrinsic or acquired multi......
RAC1 Confers Cisplatin Resistance in Esophageal Squamous Cell Carcinoma by Modulating the Warburg Ef
Objective Objectives: Esophageal squamous cell carcinoma(ESCC)occurs with high frequency in China and the prognosis is p......
Objective Chemoresistance is one of the key factors that affecting the outcome of patients with gastric cancer,and it is......
Chrysin enhances sensitivity of BEL-7402/ADM cell to doxorubicin by suppressing PI3K/Akt/Nrf2 and ER
Aim: Nuclear factor-E2-related factor 2 (Nrf2) is a redox-sensitive transcription factor regulating expression of a numb......
Background Taxol is a powerful chemotherapy agent that targets the microtubule cytoskeleton, leading to mitotic arrest a......
The NLRP3 inflammasome activated by reactive oxygen species in 5-fluorouracil-chemoresistance of ora
Objective:5-fluorouracil (5-FU) is a standard chemotherapeutic agent for local and distant metastatic oral squamous cell......
The success of chemotherapy is often limited because of the development of drug resistance.Emerging evidence has shown t......
Upregulation of Neural Precursor Cell Expressed Developmentally Downregulated 4-1 is Associated with
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Quantitative differences in protein expression between cisplatin sensitive COC1 ovarian carcinoma ce
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Gastric cancer represents a common and highly fatal malignancy,and thus a pathophysiology-based reconsideration is neces......
Cholangiocarcinoma(CCA)is a malignant tumour of the biliary system that originates from the neoplastic transformation of......
