ABCG2相关论文
目的 探讨血清溶质载体家族6成员14(SLC6A14)、三磷酸腺苷结合转运蛋白g超家族成员2抗体(ABCG2)和泛酰巯基乙胺酶(VNN1)在溃疡性结肠炎(Ul......
目的 探究ATP结合盒转运蛋白亚家族G2(ABCG2)基因对人胃癌细胞的影响,并探讨其可能的机制.方法 收集表皮生长因子2(HER2)阳性的病......
期刊
目的:探究MDR1及ABCG2基因多态性对左乙拉西坦疗效的影响.方法:选取本院2018年3月-2020年3月收治的117例癫痫患者作为研究对象,根......
目的 研究ATP结合膜转运蛋白超家族G成员2(ABCG2)、血管内皮生长因子(VEGF)及微小RNA-23a(miRNA-23a)与乳腺癌术后同侧锁骨上淋巴......
目的:探讨苗药痛风停汤对高尿酸模型大鼠的降尿酸作用及肠道ABCG2 mRNA表达的影响。方法:将SD大鼠72只随机分为正常组、模型组、苗......
目的探究三磷酸腺苷结合转运蛋白G超家族成员2(adenosine triphosphate combined transport protein G superfamily member 2 ABCG2......
学位
Objective Temozolomide(TMZ)is a first-line chemotherapeutic agent for clinical treatment of malignant gliomas,but it is ......
目的 The expression of ATP-binding cassette subfamily G member 2(ABCG2)in manycancers was correlated with development of......
目的 以往研究认为乳腺癌耐药蛋白(ABCG2)主要通过主动将化疗药物排除的方式来介导化疗耐受,本研究拟通过实验证实ABCG2 还有可能通......
Inhibitory effect of epirubicin-loaded lipid microbubbles bound with anti-ABCG2 antibody combined wi
To investigate the inhibitory effect of epirubicin (EPI)-loaded lipid microbubbles (MBs) bound with anti-ABCG2 monoclona......
Meta-analysis of ABCG2 Q141K polymorphisms association with hyperuricemia and gout in Asian populati
Objective:To evaluate the role of ABCG2 rs2231142 polymorphisms with hyperuricemia and gout in Asian population.Methods:......
目的 翼状胬肉(pterygium)作为常见眼表疾病,具有治疗难易复发的特点。有报道推测翼状胬肉中可能存在干细胞类似亚群,在特定条件下可......
Nitric oxide synthase Ⅰ (NOSI) has been reported to promote various cancer processes including chemo-resistance.However......
Impact of ABCG2polymorphisms on theclinical outcome of TKIs therapy in Chinese advancednon-small-cel
Objective The purpose of this study was to investigate the single nucleotide polymorphisms (SNPs) of ATP binding cassett......
会议
目的:肿瘤的多药耐药性严重制约着临床药物的化疗效果。产生多药耐药性的主要原因是三磷酸腺苷结合转运蛋白家族(ATP-binding casse......
Effect of abemaciclib(LY2835219)on enhancement of chemotherapeutic agents in ABCB1 and ABCG2 overexp
Multidrug resistance(MDR)is the major obstacle of the success in cancer chemotherapy.The overexpression of ATP-binding c......
多药耐药性(multidrug resistance,MDR)是肿瘤成功化疗的主要障碍.ABC 转运泵如ABCB1、ABCC1、ABCG2 过表达是介导MDR 的主要原因.......
Objective: To investigate the characteristics of breast cancer stem cells and their protein expression of RecQ family he......
Afatinib enhances the efficacy of conventional chemotherapeutic agents by eradicating cancer stem-li
Background Cancer stem cells (CSC) have garnered significant attention as a therapeutic focus, based on evidence that th......
Linsitinib (0SI-906) antagonizes ATP-binding cassette subfamily G member 2 and subfamily C member 10
Objective: Linsitinib, a novel dual insulin-like growth factor 1 (IGF-1R)/insulin receptor (IR) kinase inhibitor in phas......
Afatinib enhances the efficacy of conventional chemotherapeutic agents by eradicating cancer stem-li
Cancer stem-like cells (CSC) have garnered significant attention as a therapeutic focus, based on evidence they may repr......
Linsitinib (OSI-906) antagonizes ATP-binding cassette subfamily G member 2 and subfamily C member 10
Objective: Linsitinib, a novel dual insulin-like growth factor 1 (IGF-1R)/insulin receptor (IR) kinase inhibitor in phas......
目的:从人结肠癌细胞株中分离、鉴定结肠癌侧群细胞(side population,SP)的存在,并初步观察其生物学特性.方法:利用流式细胞仪(flow ......
Discovery of novel urea-indole derivatives as reversal agents against ABCG2-mediated drug resistance
Multidrug resistance is characterized by the resistance of cancer cells to structurally unrelated anticancer drugs....
ABCG2是一种尿酸转运蛋白,与其他转运体相比,ABCG2基因变异种类较多,其基因突变与高血尿酸水平以及痛风相关,因此对于ABCG2基因多态性......
目的 观察氟尿嘧啶(5-FU)对人结肠癌SW480细胞ABCG2表达的影响.方法 用不同药物浓度的5-FU处理SW480细胞,用CCK8法检测5-FU在SW480......
目的 分析ABCG2和空泡型ATP酶(V-ATPase)在非小细胞肺癌(NSCIC)病理分类、TNM分期、病理分级中表达的差异性以及相关性.方法对92例......
Hedyotis Diffusa Willd Overcomes5-Fu Resistance in Human Colorectal Cancer HCT-85-Fu Cells by Down-r
Previous studies have shown that Hedyotis Diffusa Willd(HDW),a traditional Chinese herbal medicine,exhibits potent a......
目的:ABCG2基因第5外显子区单核苷酸多态性位点rs2231142与中国汉族男性痛风密切相关,基于痛风易感基因存在性别差异的考虑,本研究......
目的 研究MDR1和ABCG2基因单核苷酸多态性(SNP)与结直肠癌患者伊立替康(CPT-11)化疗疗效及不良反应的关系.方法 回顾性收集北京大......
痛风是一种常见的由尿酸盐沉积引起的慢性炎症性关节炎。该文总结了最新的痛风遗传学基础,发现痛风的高风险基因多数与肾脏和肠道尿......
目的 检测人神经母细胞瘤细胞系SH-SY5Y及WN中是否存在侧群(side population,SP)细胞,并研究该SP细胞是否具有干细胞某些生物学特......
目的:研究肾移植术后患者ABCG2421C>A基因多态性对吗替麦考酚酯(MMF)所致不良反应的影响.方法:对236例患者按不良反应类型分为骨髓......
Objective: The aim of this study was to investigate the expression of ABCG2 in human gastric carcinoma and its clinical ......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
研究背景及目的化疗是治疗肿瘤的主要方法之一,而化疗引起的多药耐药是成功化疗的主要障碍。ATP结合盒膜通道转运蛋白可以利用能量......
【研究背景】肝癌是一种发生于肝脏上的恶性肿瘤,其中肝细胞肝癌(hepatocellular carcinoma,HCC)是目前发病率和死亡率最高的原发......
热应激对肉鸡的生长发育有负面影响,导致生长性能下降,发育缓慢,同时也会影响肉鸡的屠宰性能,使肉质品质下降并引起抗氧化能力损伤......
目的:探讨柯里拉京(Corilagin)对胶质瘤U251细胞和U251干细胞细胞凋亡和耐药基因ABCG2的作用,确定其对胶质瘤U251细胞迁移能力的影......
研究目的:探究ABCB1和ABCG2介导帕比司他耐药的作用机制。研究内容:肿瘤细胞的多药耐药(multidrug resistance,MDR)是恶性肿瘤诊疗......
通过建立雏鹅高尿酸血症模型,研究高蛋白日粮对雏鹅血清尿酸水平、肝脏和肾脏超微结构及ABCG2表达的影响。超微结构观察发现,对照......
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Objective:The aim of this study was to investigate the expression of ABCG2 in human gastric carcinoma and its clinical s......
[目的]探讨人肺腺癌A549细胞系SP细胞及非SP细胞亚群的生物学特性。[方法]用流式细胞仪分选出A549细胞系SP细胞及非SP细胞亚群,检......