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１７名中长跑运动员中８名服用自由基清除合剂Ｉ号配方１周后，分两组进行４００ｍ×８，间歇３分钟速度耐力训练后发现２组运动后即刻血浆和尿液ＭＤＡ含量和ＳＯＤ活性显著增高，Ｐ＜０．０１；运动后３小时ＭＤＡ含量和ＳＯＤ活性进一步增高，达峰值，Ｐ＜０．０１；运动后２４小时恢复至静息状态。相关检验提示尿液ＭＤＡ含量和ＳＯＤ活性与血浆ＭＤＡ含量和ＳＯＤ活性均呈显著正相关。用药组血浆和尿液ＭＤＡ含量显著低于对照组，Ｐ＜０．０１，ＳＯＤ活性显著高于对照组，Ｐ＜０．００１。提示自由基清除合剂Ｉ号能有效地阻抑剧烈运动引发的自由基反应，尿液ＭＤＡ含量和ＳＯＤ活性可反映血浆ＭＤＡ含量和ＳＯＤ活性的变化。
Eight of 17 long-distance runners took free radical scavenging mixture I formula one week later, divided into two groups 400m × 8, intermittent 3-minute speed endurance training and found that immediately after exercise 2 groups of plasma and urine MDA content and SOD activity (P <0.01). At 3 hours after exercise, the content of MDA and the activity of SOD increased further (P <0.01), and resumed to rest at 24 hours after exercise. Correlation test showed that urine MDA content and SOD activity and plasma MDA content and SOD activity were positively correlated. The content of MDA in plasma and urine of the treatment group was significantly lower than that of the control group (P <0.01). The activity of SOD was significantly higher than that of the control group (P <0.001). It is suggested that free radical scavenging mixture I can effectively restrain the radical reaction induced by vigorous exercise. The content of MDA and the activity of SOD in urine can reflect the changes of plasma MDA content and SOD activity.