论文部分内容阅读
目的:探讨苦参注射液在食管癌术后康复中的临床疗效。方法:60例Ⅲ期食管癌术后患者按随机数字表法分为两组,对照组予以健择联合顺铂方案化疗;试验组在对照组基础上加用复方苦参注射液20 mL,静脉滴注,每日1次,10 d为1个疗程,共治疗4个疗程。治疗结束后比较患者的不良反应、临床疗效、生存质量和3 a生存率。结果:试验组较对照组化疗后不良反应显著减轻、临床疗效高(P<0.05);试验组化疗后生存质量明显高于对照组(P<0.05);两组术后3 a生存率无明显差异(P>0.05)。结论:苦参注射液联合健择+顺铂术后化疗方案疗效确切,能够通过降低肿瘤细胞增殖作用,抑制瘤株生长等作用明显提高临床疗效,同时能减轻化疗不良反应。
Objective: To investigate the clinical effect of matrine injection in the postoperative rehabilitation of esophageal cancer. Methods: Sixty patients with stage Ⅲ esophageal cancer were divided into two groups according to random number table. The control group was given chemotherapy combined with gemcitabine and cisplatin. In the experimental group, 20 mL of compound Kushen injection and 20 mL intravenous Instillation, once daily, 10 d for a course of treatment, a total of 4 courses of treatment. After treatment, the adverse reactions, clinical efficacy, quality of life and 3-year survival rate of patients were compared. Results: Compared with the control group, the adverse reactions in the experimental group were significantly relieved after chemotherapy, with high clinical efficacy (P <0.05). The quality of life of the experimental group after chemotherapy was significantly higher than that of the control group (P <0.05) Difference (P> 0.05). Conclusion: The curative effect of matrine injection combined with gemcitabine and cisplatin is definite. It can significantly improve the clinical curative effect by reducing the tumor cell proliferation and inhibiting the growth of the tumor. At the same time, it can reduce the adverse reaction of chemotherapy.