ubiquitin相关论文
目的:研究乙型肝炎病毒X蛋白（HBx）对HepG2细胞ZO1表达水平的影响及闭锁小带蛋白1（ZO-1）对肝癌细胞迁移和侵袭的作用。方法:分别转染HBV......
Post-translational degradation of protein plays an important role in cell life.We employed chimeric molecules (dihydrote......
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A Platform Combining Various Analytical Methods to Identify the Protein-Nanoparticle Interaction Sit
Upon contact with biological matrices,the nanoparticle surfaces with high free energy are easily modified by the adsorpt......
The pivotal role of ZEB1 transcription and ubiquitination/SUMOylation of MCT4 in breast cancer and i
Objective Objective: Monocarboxylate transporter 4(MCT4),also known as SLC16A3,is a member of the MCT family.MCT4 is one......
Objective Parkinsons disease (PD) and dementia with Lewy bodies (DLB) are characterized by the accumulation of abnormal ......
BDNF-TrkB signaling mediates ubiquitin-proteasome-dependent homeostatic regulation of synaptic prote
Homeostatic regulation of synaptic properties in response to chronic alteration of neuronal activity is essential for ne......
Primary and motile cilia/flagella function as cellular antennae, receive signals from the environment,subsequently activ......
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Cullin 3 targets methionine adenosyltransferase Ⅱαforubiquitylation-mediated degradation and regulat
Cullin 3(CUL3)serves as a scaffold protein and assembles a large numberof ubiquitin ligase complexes.It is involvedin mu......
Neddylation is essential for the viability of most model organisms and involved in cancer development.In contrast with m......
Deubiquitylation and stabilization of p21 by USP11 is critical for cell cycle progression and DNA da
p21WAF1/CIP1 is a broad-acting cyclin-dependent kinase inhibitor.Its stability is essential for proper cell cycle progre......
OBJECTIVE This study aims to explore whether ER membrane-spanning ubiquitin ligase(E3)Hrd1 enhances tau degradation thro......
Parkinsons disease and dementia with Lewy bodies are characterized by the accumulation of abnormal α-synuclein and ubiq......
Study of High-level Expression of Musca domestica Cecropin with Partner Molecular in Escherichia col
Objective To utilize partner molecular for effective expressing Musca domestica cecropin,research that partner molecular......
A Proteasome Inhibitor Protein Mediates Multiple Developmental Processes and Involves in Photomorpho
The ubiquitin-26S proteasome pathway is a dominant proteolytic system and controls plant growth and development by effec......
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TRIM25 is emerging as a central factor in breast cancer due to its regulation and function.In particular,it has been sho......
Objective To investigate the protective effects and mechanism of Chinese herbal compound Tongxinluo Capsule(通心络胶囊,T......
Seed and organ size is one of important agronomic traits in plants.The characteristic size of plant seeds and organs......
Autophagic clearance of misfolded or aggregated proteins is critical to protein quality control and cellular homeost......
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STING 是胞质DNA刺激引发的天然免疫反应信号通路中的一个关键接头蛋白.由STING介导的信号通路的调控机制有待深入剖析.在本研......
Ubiquitin and the ubiquitin-like protein ATG8 are covalently attached to their respective targets via a coordinated ......
FBW7 (F-box and WD repeat domain-containing 7), the substrate-binding subunit of E3 ubiquitin ligase SCF FBW7 (a complex......
四、免疫调整T细胞和B细胞系统是承担机体特异免疫功能的淋巴细胞系统。现知T细胞的分化和成熟过程主要受胸腺及其分泌的激素控制......
Proteins that are modified by a small ubiquitin to form ubiquitin chains are dedicated to proteasomes for degradation.Mo......
Reduced point charge models of amino acids are used to model Ubiquitin(PDB: 1UBQ). They are designed(i) from local extre......
Changes of DHNl expression and subcellular distribution in A.delicisoa cells under osmotic stressQIU Quunsheng,WANG Zezh......
为研究DF-1细胞的泛素-蛋白酶体系统(UPS)是否参与新城疫病毒(NDV)在细胞中复制的过程。使用Western-blot检测感染NDV Herts/33毒......
目的探讨蛋白酶体抑制剂MG132对He La细胞增殖的影响。方法用不同浓度的蛋白酶体抑制剂MG132(1、3、5、8和10μmol/L)处理He La细......
SUMOs(small ubiquitin-like modifiers,小泛素类调节蛋白)是最近发现的一类重要的翻译后修饰蛋白,通过共价修饰底物蛋白而调节细......
AIM: To investigate the mechanism of calcyclin binding protein/Siah-1 interacting protein(Cacy BP/SIP) nuclear transloca......
Ablation of adenosine monophosphate-activated protein kinase α1 in vascular smooth muscle cells prom
AIM: Atherosclerotic calcification is highly linked with plaque instability and cardiovascular events. Adenosine monopho......
Objective: To compare gene expression profiles of nasopharyngeal carcinoma (NPC) tissue with that of control tissue by c......
Though there were a lot of reports about the totally different responses to the inhibition of ubiquitin-proteasome path......
AIM:To investigate the inhibitory effect of ubiquitin-proteasome pathway(UPP)on proliferation of esophagealcarcinoma ce......
Activating mechanism of transcriptor NF-kappaB regulated by hepatitis B virus X protein in hepatocel
AIM:To investigate the mechanism and significance ofNF-kB activation regulated by hepatitis B virus X protein(HBx)in he......
