thromboxane相关论文
Objective: Trichosanthes pericarpium injection is widely used to cure coronary heart disease, myocardial ischemia patien......
作者对不同病期的流行性出血热(EHF)75例进行了血浆前列环素(prostaglandin I_2,PGI_2)和血栓素A_2(thromboxane A_2,TXA_2)水平的......
Effect of stellate block on vasomotor factor, vascular endothelial nitricoxide synthase and pulmonar
BACKGROUND: At present, inhalation of nitrogen monoxidum (NO) or other angiotenic is widely used to cure hypoxic pulmona......
英国科学家报告,生物化学上的阿司匹林抗性因缺血性心脏病人的检查时间、检查方法而不同。不同时间的变动是指“一次试验不足以诊......
Aspirin(ASA) irreversibly inhibits platelet cyclooxygenase-1(COX-1) leading to decreased thromboxane-mediated platelet a......
Aspirin is a wonder drug that has been used for well over 100 years for its analgesic and antipyretic effects. For the p......
Role of prostacyclin receptors in the vasoconstrictor response evoked by cyclooxygenase-1 or-2 media
AIM:In the vascular wall,the metabolism of arachidonic acid(AA)catalyzed via cyclooxygenase(COX)leads to the formation o......
Objective To observe the effect of Shenmai Injection(SI)on vascular endothelial dependent diastolic function in coronary......
缺血性脑血管病可分为脑局部缺血和广泛性全脑缺血两大类。本文对脑缺血脑梗塞合并脑水肿的治疗方法,以及在缺血性脑血管病时血管......
脑梗塞的治疗药物种类颇多,但大多数只能对复杂病理生理的某一方面起作用,其疗效尚未能尽人意。新的药物正在不断被发现,实验研究......
本文从氨基酸类神经介质、单胺类神经介质、多肽类物质、前列环素和血栓素 A_2以及酶系等方面,阐述了缺血性脑卒中的生化改变问题......
INTRODUCTIONIn order to study the therapeutic mechanisms ofemodin,an extract of Rhubarb (Rhizoma et RadixRhei,a traditi......
AIM:To explore the abnormal function of platelets and therole of angelica sinensis injection(ASI)in patients withulcera......
用改进的物质分离和鉴定技术等方法,现已查明thromboxane(TXA_2)和prostacyclin(PGI_2)衍生物在某些组织中含量更为丰富,且作用比......
新近发现白细胞三烯(LTs)可引起脑血管痉挛、脑水肿,并有促血小板聚集作用,在脑血管病的发生和发展中起了重要作用。其作用机理尚......
To determine the effect of humoral factors and theirinteraction on the developement of acute hypoxie pulmonarypressor re......
Both in vivo and in vitro Hg2+ caused dose dependent inhibition of rat platelet aggregation. However, as low a dose as 8......
Further Investigation on the Role of Selenium Deficiency in the Aetiology and Pathogenesis of Keshan
Selenium supplements were not able to restore the ultrastructural changes in the myocardiurn of latent Keshan disease pa......
目的：研究５ＨＴ对ＳＴＡ２血小板聚集和释放反应的影响及可能的分子机制．方法：以透光法，介质中ＡＴＰ含量及荧光图像法评价血小板变形，聚集反应和［Ｃａ２］ｉ水平．结果......
Effects of procainamide on adenosine diphosphate-induced platelet aggregation and thromboxane B_2 pr
Turbidimetry and radioimmunoassay were used to study the effects of procainamide (PA ) onadenosine diphosphate (ADP)-ind......
Objective To ascertain whether the growth inhibitor in conditioned medium from cultured rabbit arterial cells is dlstinc......
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随着非类固醇抗炎药(NSAIDS)目用或处方的逐渐增多,医生和服用者都有必要熟悉这类药物的副作用。非类固醇抗炎药物至少有一种共同......
Thirteen goats with chronic lung lymph fistula were inflicted withsmoke inhalation injury.Thromboxane A_2(TXA_2 in term......
本文综述了抗血小板新药——底克利特的药代动力学药理学及其作用机制,并介绍了该药在冠心病、缺血性脑中风、血栓性血管疾病和血......
血栓素A_2(thromboxane A_2,TxA_2)于1975年发现,并证明是一种使血小板聚集和血管平滑肌收缩的物质,其t_(1/2)为30秒。由于当时对......
业已证明,以阿司匹林为代表药物的抗血小板疗法对脑缺血、不稳定型心绞痛和心肌梗塞等心脑血管疾病的防治有肯定疗效。其作用机理......
26只兔被随机分为治疗组和对照组:颈动脉放血至血压5.3kPa,维持90 min,复制出血性休克模型。于休克前后,输液输血(对照组)和给药(......
Extraction and Identification of Ginsenoside Re and Its Effects and Mechanism of Protecting Acute Re
This paper studies the extraction and identification of ginsenoside Re from ginseng fruits and investigates the effect a......
目的：研究普鲁卡因胺（ＰＡ）对凝血酶诱导血小板聚集和血栓素Ｂ２（ＴＸＢ２）产生的影响．方法：用比浊法和放射免疫分析法．结果：普鲁卡因胺８５，３４，１３６和５４４μｍｏｌ·Ｌ－１有明显抑制作......
目的:观察参附注射液(Shenfu injection,SF)对血栓闭塞性脉管炎(thromboangitis obliterans,TAO)模型大鼠的防治作用及其机制。方......
目的:观察阿司匹林铜对离体免胸主动脉血管平滑肌的作用。方法:取免胸主动脉条,观察阿司匹林铜对去甲肾上腺素（NE）、KCl、CaCl2诱导......
Thromboxane receptor stimulation triggers pro-inflammatory responses in endothelial cells by activat
AIM:Aberrant activation of thromboxane A2(TXA2)receptor(TPr)is reported to cause vascular inflammation and atherosclero-......
Inhibitory effects and mechanisms of high molecular-weight phlorotannins from Sargassum thunbergii o
We evaluated the effects of high molecular-weight phlorotannins from Sargassum thunbergii(STP) on ADP-induced platelet a......
阿司匹林和氯吡格雷是临床上应用最广泛的抗血小板聚集药物,但有些患者接受抗血小板聚集药物治疗,仍有心肌梗死、猝死等不良事件发......
抗血小板药大致可分为血栓素A2(thromboxane A2,TXA2)抑制剂、磷酸二酯酶抑制剂、P2Y12拮抗剂(三代噻吩吡啶不可逆以及其他可逆抑......
目的:探讨我国患病人群中阿司匹林抵抗(aspirin resistance,AR)现象,比较不同AR实验检测法对阿司匹林疗效的判断及其临床应用价值......
An inhibitor selective for collagen-stimulated platelet aggregation from the salivary glands of hard
Soluble materials of salivary glands from Haemaphysalis longicornis were found to inhibit collagen, ADP, and thrombin-s......
一、前列腺素代谢 前列腺素(PG)是一群生物活性物质。在细胞膜内以磷脂形式存在。1973年在其生物合成过程分离鉴定出中间产物即PG......
在受损血管处刹住流血的最初阶段,包括一个血管收缩降低局部血压的过程和血小板跟血管壁相互作用的过程。后者亦称为止血机制:血......
花生四烯酸(AA)对机体有类似前列腺素(PG)的广泛作用,尤其是对血液和心血管有重要的影响。AA有降低血胆固醇、舒张血管平滑肌、降......
应用药物在各环节选择性阻断血栓烷(TX)的合成从而治疗或预防脑血管病。目前认为糖皮质激素和各种钙离子拮抗剂是通过抑制磷脂酶 A......
多数学者认为,吸烟可通过多种因素导致动脉粥样硬化的发生.其中吸烟对血小板功能的影响在动脉粥样硬化的发生中具有重要作用。
Mo......
检测了血浆PC、t-PA、ATⅢ、TxB2及6-K-PGF1α,结果表明大多数AL患者存在高凝状态。PC的减低多见于M5和M2a的高白细胞AL病人;ATⅢ......
Background Aspirin is widely used in the secondary prevention of coronary artery diseases, including myocardial infarcti......
Design, Synthesis, and Activities of Novel Derivatives of Isophthalamide and Benzene-1,3-disulfonami
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Background Aspirin is widely used in the secondary prevention of coronary artery diseases, including myocardial infarcti......
Design, Synthesis, and Activities of Novel Derivatives of Isophthalamide and Benzene-1,3-disulfonami
Based on the antiplatelet aggregation mechanism and the bioisosterism principle of the reference drug picotamide, thirte......
