APOPTOSIS相关论文
PIG3 downregulation enhances the radiosensitivity of NSCLC cells by promoting G2/M cell cycle arrest
Objective:Toinvestigatethemechanismofp53-inducedgene3(PIG3)-regulationofradioresistanceinhumannon-smallcelllungcancer(NS......
Disulfiram, an aldehyde dehydrogenase inhibitor, works as a potent drug against sepsis and cancer vi
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40. The in vitro Inhibitory Effects of Acanthopanax Giraldii Harms Var. Hispidus Hoo Plant Polysacch
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33. The Study of Mechanism By Which The Telomerase Template Phosphorothioate Antisense Oligonucleoti
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Silencing miRNA-324-3p protects against cerebral ischemic injury via regulation of the GATA2/A1R axi
Previous studies have suggested that miR-324-3p is related to the pathophysiology of cerebral ischemia, but the mechanis......
TAR DNA-binding protein 43 (TDP-43) is an essential 414 amino acid protein that regulates multiple aspects of RNA biogen......
Objective:To determine whether salvianolic acid B(Sal B)exerts protective effects on diabetic peripheral neuropathy by a......
β-Elemene induces apoptosis and autophagy in colorectal cancer cells through regulating the ROS/AMPK
β-Elemene is an effective anti-cancer ingredient extracted from the genus Curcuma (Zingiberaceae familiy).In the presen......
GKK1032B from endophytic Penicillium citrinum induces the apoptosis of human osteosarcoma MG63 cells
Chemical investigation of the culture extract of an endophytic Penicillium citrinum from Dendrobium officinale,af-forded......
A network pharmacology-based strategy for predicting the protect-ive mechanism of Ginkgo biloba on d
Hallmarks of the pathophysiology of glaucoma are oxidative stress and apoptotic death of retinal ganglion cells(RGCs).Gi......
The majority of colorectal cancer patients are not responsive to immune checkpoint blockade (ICB).The interferon gamma (......
Objective: To determine the lead bioactive compound in kernel extract of Mangifera pajang and its anti-cancer activity a......
Non-Structural Protein 5 of Zika Virus Interacts with p53 in Human Neural Progenitor Cells and Induc
Zika virus (ZIKV) infection could disrupt neurogenesis and cause microcephaly in neonates by targeting neural progenitor......
Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pat
Paeoniflorin(PF),a bioactive monoterpene glucoside,has shown a variety of pharmacological effects such as anti-inflammat......
C0818,a novel curcumin derivative,induces ROS-dependent cytotoxicity in human hepatocellular carcino
Heat shock protein 90(Hsp90)is the most common molecular chaperone that controls the maturation of many oncoproteins cri......
Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor e
Mitochondria as a signaling platform play crucial roles in deciding cell fate.Many classic anticancer agents are known t......
Wogonin protects glomerular podocytes by targeting Bcl-2-mediated autophagy and apoptosis in diabeti
Diabetic kidney disease(DKD)is one of the microvascular complications of diabetes mellitus and a major cause of end-stag......
Glioblastoma multiforme(GBM)is the most malignant and lethal primary brain tumor in adults accounting for about 50％of all......
Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and ho
Acetaminophen(APAP)is a widely used analgesic and antipyretic drug,which is safe at ther-apeutic doses but can cause sev......
Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and a
Glioblastoma multiforme(GBM)in the central nervous system is the most lethal advanced glioma and currently there is no e......
目的:探讨CLC-2氯离子通道靶向阻滞对人结膜成纤维细胞(HConF)纤维化过程的抑制作用。方法:将HConF分为空白对照组、脂质体2000(Li......
目的:探讨电针对糖尿病胃轻瘫大鼠胃窦Cajal间质细胞（ICC）凋亡的影响。方法:取32只SD大鼠，分为空白对照组、模型组、电针组、胃复安组......
目的:探讨芍药苷对醋酸铅诱导海马神经元凋亡的影响及潜在机制。方法:于2020年9月，从胎鼠中分离培养原代海马神经元细胞，并利用细胞......
Toxoplasma gondii infection induces cell apoptosis via multiple pathways revealed by transcriptome a
Toxoplasma gondii is a worldwide parasite that can infect almost all kinds of mammals and cause fatal toxoplasmosis in i......
目的:探究DcR3表达在肝癌细胞凋亡和增殖中的作用。方法:本次研究将Dcr3慢病毒载体进行构建，并建立非特异性的载体，在转染成HepG2细......
Objective:The nuclear factor erythroid 2(NFE2)-related factor 2(Nrf2)is associated with doxorubicin(DOX)-induced cardiac......
目的：:探究高糖诱导体外培养的视网膜Müller细胞自噬及凋亡的变化。方法：:实验研究。将体外培养的SD大鼠视网膜Müller细胞根据不同......
目的:探讨邻苯二甲酸二丁酯（dibutyl phthalate，DBP）通过腺苷酸活化蛋白激酶/哺乳动物雷帕霉素靶蛋白（AMP activated protein kinase/m......
近年来,许多研究发现JNK信号通路能激活下游因子,调节自噬基因的表达,同时它也会影响细胞凋亡.细胞凋亡作为细胞程序性死亡方式之......
Objective: To investigate the effect of the hexane solvent fraction of Halymenia durvillei (HDHE) on triple-negative bre......
Objective:The chemo-preventative and therapeutic properties of selenium nanoparticles (SeNPs) have been documented over ......
It has been revealed that hypoxia is dynamic in hypertrophic scars;therefore, we considered that it may have different e......
Three matrine-derived alkaloids, alopecuroidine A (1), alopecuroidine B (2a) and alopecuroidine C (2b) were isolated fro......
Background::Systemic lupus erythematosus (SLE) is a complex autoimmune disease, and the mechanism of SLE is yet to be fu......
miR-101a-3p is expressed in a variety of organs and tissues and plays a regulatory role in many diseases,but its role in......
Polysaccharides are macromolecular complexes that have various biological activities.In vivo and in vitro studies have s......
目的:探讨长链非编码RNA（lncRNA）C9ORF139靶向微小RNA（miR）-24-3P/TAOK1调控急性髓系白血病（AML）细胞增殖的作用和机制。方法:AML细胞株（......
目的:探讨钙库操纵的钙离子通道（store-operated calcium entry, SOCE）抑制剂SKF96365对百草枯（paraquat, PQ）致肝肾损伤的作用。方法:......
Objective: To investigate the effect of You-Gui Yin on glucocorticoid-induced apoptosis of rat bone marrow mesenchymal s......
Objective: To elucidate the cytotoxic effect of the secondary metabolites of Barrientosiimonas humi (B. humi) on MCF-7 a......
Zhikang Capsule Ameliorates Inflammation,Drives Polarization to M2 Macrophages,and Inhibits Apoptosi
Objective:To explore the anti-inflammatory effect of the traditional Chinese medicine Zhikang capsule(ZKC)on lipopolysac......
Background::Sweat secreted by eccrine sweat glands is transported to the skin surface through the lumen. The eccrine swe......
Background:Skeletal muscle development, a long-term and complex process, is controlled by a set of the myogenic genes. C......
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Objective:Mitophagy is known to contribute towards progression of Parkinson\'s disease.Korean red ginseng (KRG) is a w......
目的:探讨正电子凋亡显像剂n 18F-2-（5-氟-戊基）-2-甲基丙二酸（n 18F-ML-10）检测顺铂诱导的肺腺癌A549细胞凋亡情况的可行性......
目的:探讨微小RNA-1（miR-1）对缺氧/复氧（H/R）心肌细胞凋亡的调节作用。方法:体外培养大鼠胚胎心脏组织来源心肌细胞株H9c2，将处于对数生......
目的:探讨在砷诱导肝细胞凋亡过程中，组蛋白H3第27位赖氨酸三甲基化（H3K27me3）水平对抗凋亡蛋白B淋巴细胞瘤-2（BCL2）基因表达的影响。方......
目的:研究X射线辐射诱导非小细胞肺癌（NSCLC) A549细胞凋亡的适应性反应，并筛选适应性反应相关的微RNA (miRNA）。方法:将NSCLC A549细......
