globin相关论文
A novel erythroid differentiation related gene EDRF1 upregulating globin gene expression in HEL cell
...
Thirty-two cases of ovarian carcinoma, two of normal ovaries, four of benign epithelial ovarian tumor, and three of bord......
目的 为了评价艾滋病的治疗效果、筛选有效治疗药物,了解患者体内病情变化,常常需要对治疗前后患者体内病毒水平进行客观的定量.方......
Relationship between insulinase activity of erythrocytes and insulin resistance in patients with typ
Objective:To investigatetherelationshipbetweeninsulinaseactivityof erythrocytes(EIA)andinsulin resistanceinpatientswitht......
HbE is the most common hemoglobin variant in the world.In compound heterozygotes,the interaction of HbE with othermutat......
Amelioration of β~(654)-thalassemia in mouse model with the knockdown of aberrantly spliced β-globin
Large amounts of aberrantly spliced mRNA from the β654 allele was present in erythroid cells, which might impair the er......
Significance of the neutrophil-lymphocyte ratio in elderly type 2 diabetic patients with coronary he
Objective To evaluate the value of the neutrophillymphocyte ratio(NLR)in elderly type 2 diabetic patients(T2DM)with coro......
DIFFERENTIATION AND MALIGNANT SUPPRESSION INDUCED BY MOUSE ERYTHROID DIFFERENTIATION AND DENUCLEATIO
To investigate the roles of mouse erythroid differentiation and denucleation factor (MEDDF), a novel factor cloned in ou......
Using isotopic labeling of human serumapotransferrin, the binding and the endocytosis of monoter-bium transferrin (TbC-a......
目的:研究成人急性白血病患者p16基因纯合缺失和甲基化变化与其表达之间的关系,探讨其在成人急性白血病发生发展中的生物学意义。......
Objective To investigate the relationship between alterations of p16 INK4a and p14 ARF genes and gastric carc......
Comparative study of proteome between primary cancer and hepatic metastatic tumor in colorectal canc
AIM:To identify the differential proteins associated withcolorectal cancer genesis and hepatic metastasis.METHODS:Hydro......
AIM: To study effects of chebulinic acid on erythroid and megakaryocytic differentiation in K562 cells. METHODS: The be......
目的观察EDRF1基因在HEL细胞中对红细胞终末分化和珠蛋白表达的扮演的角色.方法构建EDRF1真核正义和反义表达载体,转染HEL细胞并筛......
Dear Editor, The retina is one of the highest oxygen-consuming tissues in the body because the visual process in the ver......
Objective: To analyze the proteomic characteristics of Gan (肝))--ssttaaggnnaannccyy syndrome ((GGSSSS)) by seeking the ......
The binding of nuclear proteins prepared from mouse erythroid tissue in different developmental stages to the 5’-flanki......
The pattern of high mobility group proteins 1 and 2 (HMG1,2) interaction with the 5’-flanking sequence of the human β......
A DNA-binding protein factor in K562 nuclear extract interacts with positive control region (PCR) in
It has been known that there are at least three regulatory regions (NCR1, NCR2 and PCR) in the 5’-flanking sequence (fr......
IgG抗体的调理活性对于静脉内注射免疫球蛋白用于严重细菌感染的治疗十分重要。为此,世界卫生组织生物标准化委员会最近提议,静脉......
The human ε-globin gene is expressed in a tissue-specific and developmental stage-specific manner. During the earliest......
The initiation of cellular differentiation is symbolized by the selective expressionof the specific functional proteins......
本文从一些多态位点中筛选出在中国人群中，对于同一种限制酶HaeⅢ酶解都能检出良好多态性的三个单位点探针（PMLJ14、PYNH24、α－globi......
Retroviral mediated gene transfer of humanglobin gene into hematopoietic stem cells is apromising approach for thalasse......
Ｅｆｅｃｔｏｆｓｍａｌｅｒｙｔｈｒｏｉｄｅｎｈａｎｃｅｒｆｒａｇｍｅｎｔｏｎｅｘｐｒｅｓｉｏｎｏｆｔｒａｎｓｆｅｒｒｅｄβ┐ｇｌｏｂｉｎｇｅｎｅｉｎＭＥＬｃｅｌｓＴａｏＪｉｚｈｏｎｇ陶吉中，ＬｉｕＤｅｐｅｉ刘德培，ＷｅｉＱｉｚｅ韦启泽，ＺｈａｉＪｉｎ...
Efectofsmalerythroidenhancerfragmentonexpresionoftransferredβ┐globingeneinMELcelsTaoJizhong......
By electrophoretic mobility shift assay (EMSA), the effect of point mutation C→T at - 64 of human δ-globin gene on it......
Interactions between GATA transcription factors and the DNasel hypersensitive sites in the human p-g
In this study, we analyze the binding of nuclear proteins isolated from the hydroxyurea (Hu)-induced and uninduced HEL ......
Adeno-associated virus-mediated integration and expression of humanβ-globin gene with the core fragm
To improve the integration stability and expression of the transferred human β- globin gene, the two recombinant adeno......
HEL cells, a human erythroleukemia cell line, mainly express the fetal (r)globin gene and trace amount of the embryonic ......
Identification of a NF-кB site in the negative regulatory element (ε-NRAII) of human ε-globin gene a
The developmental control of the human e-globin gene expression is mediated by transcription regulatory elements in the ......
Objective To evaluate the expression and function activity of P-glycoprotein (P-gp) in human mononuclear cells (MNCs) in......
The expression, purification and spectra char-acterization of recombinant human neuroglobin (NGB) are reported. The pET3......
Protective effects of salvianolic acid A, schisan- henol, and FLZ-52 A on oxidative stress induced i
AIM: Since oxidative stress played an important role in neuronaldegenerative diseases such as Parkinson’s disease and ......
Effect of Yisui Shengxue Granule (益髓生血颗粒) on the Oxidative Damage of Erythrocytes from Patients with
Objective:To investigate the effect of Yisui Shengxue Granule(益髓生血颗粒,YSSXG),a complex Chinese medicine,on the oxid......
目的通过基因打靶建立c-myb+/+和c-myb+/-胚胎干细胞(ES)模型,了解转录因子c-myb在造血定型和分化中的作用。方法采用去除白血病抑......
Single nucleotide polymorphism is an interesting problem that can alter gene expression,recode amino acids and affect pr......
目的探讨海南汉族人群谷胱甘肽S转移酶GSTM1基因和GSTT1基因多态性分布情况。方法应用多重PCR扩增方法检测147名汉族健康人群GSTM1......
正常淋巴细胞在发育中是多克隆性质,但恶性肿瘤表现为单克隆性基因重排.所以,通过基因重排检测不仅可以鉴别淋巴组织是肿瘤性增生......
On-line parallel reversed phase two-dimensional liquid chromatography for high-throughput analysis o
A comprehensive two-dimensional liquid chromatographic system (2D SCX/RP) is con- structed with a 10-port-2-way valve us......
The developmental stage-specific silencing of the human ε-globin gene during embryonic life is controlled, inpart, by t......
APPLICATION OF HIGH PRESSURE LIQUID CHROMATOGRAPHY AND MICROSEQUENCING METHODOLOGY IN THE STRUCTURAL
This paper reports the results of the analyses of 17 different Hb variants which were observed in 37 families. High pre......
Utilizing restriction endonuclease mapping and blot bybridization, we have determined the arrangement of the α-globin ......
STUDIES ON THE CELL PHENOTYPE CHARACTERISTICS OF HYBRID CELLS CROSSED BETWEEN RAT NUCLEATED ERYTHROB
The present study is designed to investigate the regulatory effect of mammalian erythroblasts, prior to naturally-occurr......
Our previous studies have identified that there are at least three regulatory regions (two negative regions and one posi......
我们发现,一种在RNA干扰实验中用作阴性对照的商业化siRNA具有明显的诱导人慢性髓性白血病K562细胞系向红系方向分化的作用.它表现......
AIM:to study the prevalence of human papillomavirus(HPV) in esophageal carcinoma in tangshan,China,a high-incidence area......
本文通过对荣华二采区10...
自Kegen(1967年)报告肌红蛋白(Myo-globin简称Mb)作为心肌损伤的指标以来,临床上己相继报道用血清Mb 作为早期诊断急性心肌梗塞的......
With the support by the National Natural Science Foundation of China and the National 973Program,the research group led ......
