RHOA相关论文
目的：研究半枝莲石油醚提取物对EGF诱导的人三阴性乳腺癌细胞株（MDA-MB-231）Ezrin和Rho A蛋白表达的影响，探讨其抑制三阴性乳腺癌细胞......
目的 探讨基于益气补虚法通过实验验证全真一气汤多糖对心力衰竭(chronic heart failure,CHF)大鼠心肌凋亡及RhoA表达情况的影响.......
目的 观察腺嘌呤诱导大鼠慢性肾病模型中HIF-1α、RhoA和SOX9的表达及其与肾间质纤维化的关系.方法 将20只大鼠随机分为对照组(Con......
第一部分LPS诱导人气道上皮细胞炎症反应中miR-223表达变化及对NF-κB活性的调控目的 本实验借助内毒素脂多糖（LPS）刺激体外培养的人......
在中国,冠状动脉粥样硬化性心脏病具有较高的发病率和死亡率。冠状动脉旁路移植术可以有效的治疗冠状动脉粥样硬化性心脏病,缓解心......
研究目的:抑郁症作为一种常见的疾病,其核心症状为持续性的情绪低落,缺乏动力,意志消沉,最严重时可导致自杀。产前应激（prenatal st......
动脉粥样硬化( atherosclerosis,AS)是一种以动脉内膜斑块为特征的血管类疾病.据统计,AS是导致我国严重心血管疾病的常见病理因素......
目的 研究四磨汤与功能性消化不良模型大鼠胃RhoA及ROCK的关系,探讨其治疗机制.方法 通过碘乙酰胺灌胃、孤养及平台站立剥夺睡眠制......
Endogenous sulfur dioxide attenuates hypoxia-induced pulmonary artery hypertension via promoting the
Background Endogenous sulfur dioxide (SO2) is a novel gasotransmitter involved in the pathophysiologic process of pulmon......
RhoA蛋白作为一种重要的小GTP酶蛋白,在细胞内受到多种蛋白精细且复杂的调控,使其在GTP结合活性状态及GDP结合非活性状态之间相互......
背景与目的:骨肉瘤发病率高、恶性程度高、易转移,其中远处转移是导致患者疗效不佳和预后不良的重要因素。他汀类药物主要用于降血......
目的:双酚A（Bisphenol A,BPA）是一种高产量（high production volume,HPV）化学品,常用于食品包装材料、牙科密封剂、医疗器械和热载体。......
背景:胃癌（gastric cancer,GC）是一种常见的消化系统恶性肿瘤,其发病率和病死率均居于高位,且由于缺乏早期诊断的生物学标志物,胃癌......
[目的]1、探讨RhoA蛋白在人体胆囊癌组织的表达情况。2、通过体外细胞实验研究RhoA基因干扰对胆囊癌细胞增殖、迁移和侵袭的影响。......
目的:通过观察不同时机夹脊电针介入下,大鼠脊髓横断区RhoA蛋白的时相表达变化、大鼠后肢运动功能的恢复情况,进而研究夹脊电针对......
大脑皮层的发育经历神经前体细胞增殖,极化,有丝分裂后神经元的正常迁移和准确定位,新生神经元在时间和空间上的迁移和定位,对大脑......
目的 探究竹沥对肝纤维化小鼠Ras同源基因-Rho相关螺旋卷曲蛋白激酶(Ras homologous gene-Rho-associated coiled-coil containing......
背景:骨关节炎的重要病理变化是关节软骨的退变,转化生长因子β1和Ras同源基因家族成员A分别在维持关节软骨稳态和骨关节炎的发生......
目的 探讨热休克蛋白27(heat shock protein 27,HSP27)调控RhoA在大鼠膀胱出口梗阻(bladder outlet obstruction,BOO)致平滑肌重塑......
目的:构建肿瘤坏死因子(TN F-α)诱导的足细胞损伤模型,观察不同浓度、相同浓度和不同诱导时间对足细胞Synaptopodin、14-3-3β、R......
目的 探讨葡萄籽原花青素(grape seed proanthocyanidins,GSP)对苯肾上腺素(phenylephrine,PE)诱导的乳鼠心肌肥大的保护作用及其......
背景中风是目前最常见的死亡原因之一,也是在全世界范围内持续性和获得性残疾的主要原因,随着人口变化,发病率进一步增加,对人们生......
在脊椎动物中,Mir-133调控心肌细胞和骨骼肌细胞的增殖和分化.本研究利用miR-RACE技术验证了pm-miR-133序列的准确性并通过stem-lo......
研究模拟微重力(SMG)对骨髓间充质干细胞(BMSCs)形态、细胞骨架、粘附性的影响,探讨RhoA 活性与模拟微重力效应之间的关系.在模拟......
Objective: To verify the interaction between SCYL1BP1 and RhoA, analyze the contribution of RhoA transcription level reg......
Activation of protease-activated receptor-2 elicits epithelialmesenchymal transition in HBE cells vi
Aims As a critical event involved in the airway remodeling,epithelial-mesenchymal transition(EMT)of bronchial epithelial......
Analyses of clinicopathological features and survival of gastric cancer patients with RHOA mutations
Objective The TCGA molecular classification of gastric cancer(GC)were published in 2014,in which GC can be classified in......
The development of dendrites involves several discrete morphological steps, which depends on the regulation of the cytos......
The rapid and efficient conduction of action potentials requires morphological integrity and correct function of insulat......
Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+-dependent cofilin acti
Olfactory ensheathing cells (OECs) migrate from the olfactory epithelium towards the olfactory bulb during development.H......
Background: This study investigated the effect of annexin Ⅴ on the proliferation of primary rat Leydig cells and the po......
fibronectin upregulation in mesangial cells involves caveolin-1-dependent RhoA-GTP activation via Sr
Background:Increasing evidence indicates that diabetic-mediated renal interstitial fibrosis through extracellular matrix......
The purposes of this study were to investigate the potential roles of miR-200b in regulating RMP7-induced an increase in......
目的 研究 RhoA 在介导力学信号调控新骨形成中的作用，为探索临床中高效稳定的牵张成骨治疗方法提供理论依据。方法 分离培养并鉴定......
研究目的：肝细胞生长因子(hepatocyte growth factor,HGF)是一种多效生长因子,在牙胚发育过程中起着重要的作用,本实验对其在牙乳头......
Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+-dependent cofilin acti
Olfactory ensheathing cells (OECs) migrate from the olfactory epithelium towards the olfactory bulb during development.H......
Roles of protein kinase C and RhoA in the opening of blood-tumor barrier induced by low-dose endothe
Objective This study was performed with an in vitro blood-tumor barrier (BTB) model to investigate whether protein kinas......
Neurons have characteristic dendritic arborization patterns that contribute to information processing.Here we show that ......
Object: To proved whether microRNA (miRNA)146a is a negative regulator of MDA-MB-231 breast cancer cells.And to confirn ......
目的：研究牙髓细胞迁移和分化的先后时相关系，探讨Rho/ROCK信号通路对牙髓细胞迁移和分化及其时相关系的调控作用。材料及方法：使用TG......
RhoA/ROCK pathway regulates canonical transient receptor potential channels in hypoxic pulmonary vas
Aim: Hypoxic pulmonary vasoconstriction (HPV) can be modulated through either elevation of [Ca2+]i by Ca2+-dependent mec......
目的:研究高压氧治疗对MCAO大鼠脑组织RhoA蛋白在各个时间点的表达强度变化、结合神经功能评分的影响,探讨RhoA在脑缺血后神经功能......
目的探讨RhoA/Rho激酶1(ROCK1)下调抑制肌球蛋白轻链(MLC)磷酸化在主动脉夹层(AD)形成过程中的作用。方法检测正常(NA)和AD主动脉......
RhoA作为Rho蛋白家族中的代表成员，在恶性肿瘤的发生、发展过程中起重要的调控作用。既往研究表明，RhoA在调节肌动蛋白聚合、细胞骨......
目的探讨机械生长因子(MGF)调控骨髓间充质干细胞(MSCs)迁移作用机制。方法分离Sprauge-Dawley(SD)大鼠的MSCs，外源性给予不同浓度(......
