NEUROTROPHIC相关论文
Tripchlorolide protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotox
Many current theories of Parkinson s disease (PD) suggest that inflammation is involved in the neurodegenemtive process.......
Hyperbaric oxygen improves functional recovery of rats after spinal cord injury via activating strom
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Dysfunctional autophagy often occurs during the development of neurodegenerative diseases,such as Parkinson’s disease,H......
Effects of a multimodal exercise protocol on functional outcomes,epigenetic modulation and brain-der
Epigenetic changes have been shown to be associated with both aging process and aging-related diseases.There is evidence......
Hippocampal insulin resistance and the Sirtuin 1 signaling pathway in diabetes-induced cognitive dys
In the peripheral nervous system,the activation of Sirtuin 1 can improve insulin resistance;however,the role played by S......
Neurotrophic and metabotrophic potential of nerve growth factor and brain-derived neurotrophic facto
One of biggest recent achievements of neurobiology is the study on neurotrophic factors. The neurotrophins are exciting ......
目的探讨脑源性神经营养因子(brain-derived neurotrophic factor,BDNF)基因多态性与颞叶癫癎的相关性。方法采用提取DNA、聚合酶......
Low-frequency transcranial magnetic stimulation is beneficial for enhancing synaptic plasticity in t
In the aging brain, cognitive function gradually declines and causes a progressive reduction in the structural and funct......
Transplantation of stem cell-derived astrocytes for the treatment of amyotrophic lateral sclerosis a
Neglected for years, astrocytes are now recognized to fulfill and support many, if not all, homeostatic functionsof the ......
Effect of Tongluojiunao injection made from Sanqi(Radix Notoginseng) and Zhizi(Fructus Gardeniae) on
OBJECTIVE: To explore the effect of Tongluojiunao injection(TLJN) prepared with Sanqi(Radix Notoginseng) and Zhizi(Fruct......
Micro RNA-124 contributes to neurogenesis through regulating its targets,but its expression both in the brain of Hunting......
兔子是由有高神经生长的以前净化的蛋白质的 immuned 因素(NGF ) bioactivity (象 NGF 一样朊酶) fromAgkistrodon halys 智慧女神......
Gadolinium (Gd3+) complexes are important contrast agents in medical magnetic resonance imaging (MRI) and of great poten......
AIM To assess the relationship of brain-derived neurotrophic factor(BDNF) with cognitive impairment in patients with typ......
To explore the role of insulin-like growth factor 1 (IGF-1) gene expression abnormality in neurotrophic causes of diabet......
c-Jun NH2-terminal kinase(JNK)-interacting protein 3 plays an important role in brain-derived neurotrophic factor/tropom......
Therapeutic potential of brain-derived neurotrophic factor(BDNF) and a small molecular mimics of BDN
Traumatic brain injury(TBI) is a major health problem worldwide.Following primary mechanical insults,a cascade of second......
Effect of adenovirus-mediated brain derived neurotrophic factor in early retinal neuropathy of diabe
AIM:To observe effect of adenovirus-mediated brain derived neurotrophic factor in early retinal neuropathy of diabetes i......
左心室肥厚(LVH)及其继发的充血性心力衰竭是当前致使人类残疾和死亡的主要原因之一,肥胖既是心血管疾病的危险因素,也是引起LVH的......
目的建立适于生产应用的重组人睫状神经营养因子(recombinant human ciliary neurotrophic factor,rh CNTF)纯化工艺,并对纯化产物......
期刊
MiR-206 decreases brain-derived neurotrophic factor levels in a transgenic mouse model of Alzheimer&
MicroRNA alterations have been reported in patients with Alzheimer ’s disease(AD) and AD mouse models. We now report th......
Over last 20 years, extracellular matrices have been shown to be useful in promoting tissue regeneration. Recently, they......
Normalization of ventral tegmental area structure following acupuncture in a rat model of heroin rel
Drugs can cause obvious damage to the brain. To verify the relationship between acupuncture, neurotrophic factor express......
Long-term potentiation(LTP)at synapses between primary afferents and spinal dorsal horn neurons induced by noxious elect......
Effect of ciliary neurotrophic factor on bcl-2 and c-jun gene and protein expression in cultured ret
BACKGROUND:In various retinal neurodegenerative animal models,ciliary neurotrophic factor (CNTF) exhibits prominent neur......
Protective effects of nerve regeneration factor and brain-derived neurotrophic factor on retinal gan
BACKGROUND:Previous studies have shown that nerve regeneration factor (NRF) provides neuroprotective effects. However,th......
TrkB and p-trkB expression in brain-derived neurotrophic factor-pretreated rat retina following acut
BACKGROUND: Exogenous brain-derived neurotrophic factor (BDNF) promotes retinal ganglion cell survival. However, the pro......
Neuroprotective effects of BDNF and GDNF in intravitreally transplanted mesenchymal stem cells after
● AIM: To assess the neuro-protective effect of bone marrow mesenchymal stem cells(BMSCs) on retinal ganglion cells(RGC......
OBJECTIVE: To summarize and analyze the factors and theories related to the attack of motor neuron disease, and comprehe......
目的研究经颅磁刺激(transcranial magnetic sti mulation, TMS)对脑梗死大鼠神经功能恢复和皮层脑源性神经营养因子(Brain derive......
Synergistic effects of brain-derived neurotrophic factor and retinoic acid on inducing the different
BACKGROUND: Under induction of retinoic acid (RA), bone marrow stromal cells (BMSCs) can differentiate into nerve cells ......
Sexual differences of the effects of prenatal stress on the expression of extracellular signal-regul
BACKGROUND: Prenatal stress has been shown to inhibit cell proliferation in the dentate gyrus and hippocampus, reduce hi......
OBJECTIVE: Recently, with the development of biological and artificial materials, the experimental and clinical studies ......
创伤性脑损伤(traumatic brain injury,TBI)占全身创伤发生率的第二位,已成为发达国家儿童和青年人伤病致死的首要原因[1]。颅脑创......
Upregulation of glial cell line-derived neuro- trophic factor mRNA levels in ischemic cerebral corte
Glial cell line-derived neurotrophic factor (GDNF), a distant member of the transforming growth factor-βsuperfamily, h......
Objective:To investigate the changes of brain derived neurotrophic factor(BDNF) in hippocampus of chronic lead exposed r......
Gonadectomy affects brain derived neurotrophic factor in rats after chronic constriction nerve injur
AIM: To assess the effect of gonadectomy on brain derived neurotrophic factor (BDNF) expression in neuropathic pain. MET......
1 前言学习记忆是一个复杂的过程。它不仅包括突触传递及相关的信号事件,而且涉及突触的可塑性和基因转录后新蛋白质的合成。有关......
目的:干细胞特别是神经干细胞移植治疗神经系统疾病在动物实验中已得到了证实,这为临床神经系统疾病的治疗尤其是其功能的恢复带来......
BACKGROUND: Insulin receptor (IR) expression in the substantia nigra of patients with Parkinson disease (PD) is not only......
OBJECTIVE: To explore the effect of progesterone on peripheral nerve regeneration. DATA SOURCES: An online search of Med......
Objective: To investigate telomerase activity in rabbit bone marrow stromal cells ( BMSCs ) during their committed diffe......
Brain-derived neurotrophic factor inducing angiogenesis through modulation of matrix-degrading prote
Background Recent studies have proved that brain-derived neurotrophic factor (BDNF) possesses angiogenic activity in vit......
AIM:To observe the effects of mouse nerve growth factor(NGF),rat recombinant brain derived neurotrophic factor(rm-BDNF)......
Olfactory ensheathing cell transplantation in 106 patients with old spinal cord injury Differences i
BACKGROUND: It has been demonstrated that the transplantation of olfactory ensheathing cell (OEC) can promote the recove......
OBJECTIVE: Studies on the repair of peripheral nerve injury have achieved great progresses in recent years. Clinical ner......
Brain-derived neurotrophic factors increase the proliferation and differentiation of endogenous neur
BACKGROUND: It has been confirmed that brain-derived neurotrophic factor (BDNF) can promote the proliferation of neural ......
Intrastriatal glial cell line-derived neurotrophic factors for protecting dopaminergic neurons in th
BACKGROUND:Substantia nigra is deep in position and limited in range,the glial cell line-derived neurotrophic factor(GDN......
