RGCs相关论文
目的:青光眼是一种不可逆的致盲眼病,它的主要特征是视神经损伤和视网膜神经节细胞（Retinal ganglion cells,RGCs）进行性变性。如今,......
目的 观察补精益视片对自发性青光眼模型DBA/2J小鼠RGCs的SIRT1组蛋白去乙酰化酶表观遗传调控影响,探索其干预RGCs凋亡的新机制.方......
Purpose Retinal ischemia/reperfusion(I/R)injury has been implicated in many ocular diseases,because it leads to retinal ......
糖尿病视网膜病变是人类最主要的致盲原因之一.近年来的临床和基础研究发现糖尿病患者和动物模型在视网膜特征性微血管发生改变以......
青光眼是全球主要的不可逆性致盲眼病之一。在 中国原发性青光眼的全民患病率约为0.5％,年龄超过40岁的人群中,其发病率逐高达2％左右......
Purpose:To set up the Sharma’s chronic intraocular hypertension model and investigate the intraocular pressure (IOP) as......
<正>视觉信息在眼与大脑之间传递的途径由视网膜神经节细胞(retinal ganglion cells,RGCs)发出的轴突组成,这些连接的建立是在发育......
目的:明确Lhx8在SD大鼠切割穹窿海马伞后海马齿状回颗粒下层和门区中的表达变化。方法:切割SD大鼠穹窿海马伞,成功制备海马去神经......
Tonicity response element binding protein associated with neuronal cell death in the experimental di
AIM: To study the contribution of tonicity response element binding protein(Ton EBP) in retinal ganglion cell(RGC) death......
Abstract：The tomato Pto gene encodes a serine/threonine kinase （STK） whose molecular characterization provides valuable ins......
视神经损伤可由多种因素引起,如外伤、青光眼、炎症、缺血及肿瘤等.损伤导致视网膜神经节细胞(retinalganglion cells,RGCs)继发性......
Effects of minocycline on apoptosis and neuronal changes in retinal ganglion cells from experimental
BACKGROUND: Minocycline, a tetracycline derivative, is neuroprotective in models of various neurological diseases. OBJEC......
为研究脑源性神经生长因子(BDNF)干预对急性高眼压后大鼠视网膜磷酸化的细胞外信号调节激酶(p-ERK1/2)表达变化的影响,本实验将成......
目的量化评价特异性半胱氨酸蛋白酶-3(caspase-3)抑制剂z-DEVD-FMK治疗外伤性视神经损伤的疗效,并分析相关因素。方法将144只中国......
目的:观察低氧(Hypoxia,Hyp)对大鼠视网膜神经节转化细胞(retinaganglioncell-5,RGC-5)氧化应激损伤的影响及牛磺酸(Taurine,Tau)......
近年来,青光眼的研究焦点已转向神经保护。各种以不同的神经保护药物为基础的实验研究结果表明,神经保护治疗能减少视网膜神经节细......
Neuronal changes in the retinal ganglion cell layer following recombinant human interleukin-2 intrav
Intraperitoneal injection of recombinant human interleukin-2(rhIL-2) inhibits neuronal apoptosis in the chronic ocular h......
Retinal ganglion cell death in a DBA/2J mouse model of glaucoma Microglial activation and intraocula
BACKGROUND:Retinal microglia has been shown to reactivate in a murine model of pigmentary glaucoma.However,the relations......
视神经损伤是眼科常见疾病,多并发于颅脑外伤,预后不良,常致患者失明。由于视神经损伤的发病机制尚未完全明了,所以迄今为止其治疗......
目的研究皇家外科学院大鼠(royal college of surgeon rat,RCS)视网膜变性过程中α亚型视网膜神经节细胞(retinal ganglion cells,......
视网膜神经节细胞(RGCs)的过度凋亡是青光眼病理改变的基础。Mller细胞作为视网膜的主要神经胶质细胞,对于维持神经元的完整性、......
α-晶状体蛋白是晶状体中重要的成分蛋白质,是由αA-和αB-亚基组成的四聚体蛋白质。近年来研究表明α-晶状体蛋白具有很多特性,包......
Neuroprotective effects of BDNF and GDNF in intravitreally transplanted mesenchymal stem cells after
● AIM: To assess the neuro-protective effect of bone marrow mesenchymal stem cells(BMSCs) on retinal ganglion cells(RGC......
青光眼是一组以特征性视神经萎缩和视野缺损为共同特征的疾病,是主要的致盲性眼病之一,青光眼动物模型的建立为研究该病的发生发展......
许多致盲性眼病是由视网膜神经节细胞(RGCs)损伤造成的,目前临床上缺乏有效的治疗方法.最近的研究显示干细胞可以替代或再生RGCs,......
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For the first time we have shown here that the constituent from tectal extract (Te) which can support and promote the s......
Neuroinflammation in glaucoma:soluble tumor necrosis factor alpha and the connection with excitotoxi
Inflammation is a complex and highly regulated response that occurs early after infection or injury.This process is init......
Past,present and future of preserving and restoring function in the visual system: removing galectin
Great advances in retinal ganglion cells survival(RGCs),optic nerve preservation and regeneration have been made in the ......
着重介绍视网膜神经节细胞 (RGCs)的培养、分离、鉴定及影响因素等方面的新进展。RGCs的培养分为视网膜外植块培养、分离的RGCs细......
目的 探讨银杏叶提取物GBE 50(Ginkgo biloba extract 50)对大鼠视神经钳夹伤后视网膜神经节细胞(RGCs)的保护作用.方法 65只SD大......
目的观察血府逐瘀汤对大鼠外伤性视神经损伤的保护作用。方法27只健康SD大鼠随机分为A、B、C3组,均用微型视神经夹制作成单眼视神......
Achyranthes bidentata polypeptides(ABPP) have been reported to inhibit apoptosis of retinal ganglion cells(RGCs).The pre......
AIM: To observe the effect of Lycium barbarum polysaccharide (LBP) on rat retinal ganglion cells (RGCs) in vitro. METHOD......
Lycium barbarum, a traditional Chinese anti-aging herb, has been shown to protect retinal ganglion cells (RGCs) in a rat......
AIM:To investigate the role of O-GlcNAcylation of nuclear factor-kappa B(NF-κB) in retinal ganglion cell(RGC) death and......
Accumulating evidence supports an important role for nerve growth factor(NGF) in diabetic retinopathy.We hypothesized th......
This study aimed to modify the mixed and purified culture of rat retinal ganglion cells(RGCs) in vitro.The retinae of 1-......
在脊椎动物的视觉系统中,信息的初级处理发生在视网膜。随着多电极记录技术的发展,视网膜神经节细胞的协同活动在不同物种中被广泛......
Extraction(DSX) from Erigeron breviscapus modulates outward potassium currents in rat retinal gangli
AIM: To investigate the effect of DSX, an active component extracted from Erigeron breviscapus, on the voltage-gated out......
激活大麻素CB1受体(CB1Rs)通过调控多种离子通道,从而调节脊椎动物视网膜的功能。本文旨在利用膜片钳全细胞记录技术,在大鼠视网膜......
The retina and its development:The retina is an essential part of the visual system.A myriad of eye diseases are charact......
During cerebral cortical cortex neurogenesis two major types of progenitors generate a variety of morphologically and fu......
Neuroprotective effect of edaravone in experimental glaucoma model in rats: a immunofluorescence and
AIM: To evaluate the neuroprotective activity of systemically administered edaravone in early and late stage of experime......
