论文部分内容阅读
本文研究12例健康者(6男6女)摄入含40%脂肪的标准早餐后胆囊排空和再充盈与胃排空固体食物、胃肠道通过时间及血清胰多肽反应之间的关系。用实时超声测量胆囊的体积、排空和再充盈状态。摄入用硫化~(99m)锝胶体标记的鸡蛋,通过检测放射性从胃内消失时间以测定固体食物从胃内排空的情况。摄入10 g乳果糖(lactulose)后测定从呼吸中最初释放出氢气的时间以判断胃肠道通过时间。空腹及进餐后每30分钟取血一次用放射免疫法测血清胰多肽。结果显示胆囊排空呈双相反应,进餐后0～30分钟为快相,排空率为0.015±0.003/min,与胃快速排空液体食物有关;30～120分钟为慢相,排空率为0.006±0.001/min,胆囊保持收缩状态,直至进餐后249±67分钟开始再充盈;至335±52分钟时胆囊重新充盈,达
This study was to investigate the relationship between emptying and refilling of gallbladder after gastric emptying and solid food evacuation, transit time of gastrointestinal tract, and serum pancreatic polypeptide response in 12 healthy subjects (6 males and 6 females) after standard breakfast with 40% fat. Gallbladder volume, emptying and refilling were measured with real-time ultrasound. Eggs labeled with sulfurized ~ (99m) technetium colloid were ingested and the emptying of solid food from the stomach was determined by measuring the time of disappearance of radioactivity from the stomach. After ingestion of 10 g of lactulose, the time from the initial release of hydrogen from the breath was measured to determine the transit time of the GI tract. Fasting and eating blood every 30 minutes after a meal with radioimmunoassay of serum pancreatic polypeptide. The results showed that the gallbladder emptying was biphasic reaction, 0 to 30 minutes after eating fast phase, the emptying rate was 0.015 ± 0.003 / min, and the rapid emptying of the stomach related to liquid food; 30 to 120 minutes for the slow phase, emptying rate 0.006 ± 0.001 / min, the gallbladder maintained in a contractile state until 249 ± 67 minutes after the meal began to refill; by 335 ± 52 minutes the gallbladder was refilled, reaching