Treatment of severe Clonorchiasis sinensis by endoscopic nasobiliary drainage and oral praziquantel

来源 :World Journal of Gastroenterology | 被引量 : 0次 | 上传用户:yaczxxzx
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AIM:To assess the therapeutic value of endoscopicnasobiliary drainage(ENBD)and oral praziquantel forsevere Clonorchiasis sinensis infection.METHODS:Of the 84 Clonorchiasis sinensis-infectedpatients enrolled,58 were treated with ENBD(as observinggroup,ENBD group),26 received operations(control group,operation group).Both of the two groups were comparablein terms of patient’s age,body mass index.Before andone week after treatment,the average diameters ofcommon bile ducts were measured by ultrasound,andserum bilirubin,ALP,γ-GT and ALT were detected bybiochemical methods.After ENBD or operation,the patientstook praziquantel for two days.RESULTS:Compared with the patients in operation group,ENBD patients in ENBD group had higher recovery rates ofabdominal pain and fever as well as jaundice,quicker remission,smaller trauma,fewer complications and lower cost.CONCLUSION:ENBD combined with oral praziquantel isan effective and safe method for the treatment of severeClonorchiasis sinensis. AIM: To assess the therapeutic value of endoscopic nasobiliary drainage (ENBD) and oral praziquantel forsevere Clonorchiasis sinensis infection. METHODS: Of the 84 Clonorchiasis sinensis-infected patients enrolled, 58 were treated with ENBD (as observing group, ENBD group), 26 received operations (control group, operation group) .Both of the two groups were comparablein terms of patient’s age, body mass index.Before andone week after treatment, the average diameters ofcommon bile ducts were measured by ultrasound, andserum bilirubin, ALP, γ-GT and ALT were detected bybiochemical methods. After ENBD or operation, the patient protocol praziquantel for two days. RESULTS: Compared with the patients in operation group, ENBD patients in ENBD group had higher recovery rates ofdominal pain and fever as well as jaundice, quicker remission, smaller trauma, fewer complications and lower cost. CONCLUSION: ENBD combined with oral praziquantel isan effective and safe method for the treatment of severe Clonorchiasis sinensis.
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