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目的探究盐酸二甲胺四环素软膏治疗牙周病的临床疗效。方法选择某院2010年1月～2011年6月收治的50例患者,共计72颗患牙,对所有患者行日本SUNSTAR INC株式会社生产的派力奥牙科盐酸二甲胺四环素软膏治疗,观察临床症状治疗效果、牙周袋深度、牙齿松动度、龈沟出血指数等临床指数变化。结果治疗1个月后的牙龈炎症、牙周脓肿、溢脓、牙齿松动上疗效显著。龈沟出血指数、牙周指数明显下降,同时牙周疾病中牙周炎、牙周脓肿、智齿冠周炎的临床疗效显著,临床疗效有效率为97.2%。结论派力奥牙科盐酸二甲胺四环素软膏是目前治疗牙周疾病的首选治疗措施,可以有效抑制牙周菌斑,抑制宿主反应,其疗效作用强,不易产生耐药性,且副作用小,值得在临床上应用于推广。
Objective To investigate the clinical effect of minocycline hydrochloride ointment on periodontal disease. Methods A total of 72 patients with 50 patients admitted to our hospital from January 2010 to June 2011 were enrolled. All patients were treated with Palio Dental Minocycline Hydrochloride Tetracycline Ointment manufactured by Japan SUNSTAR INC. Symptoms of treatment effect, periodontal pocket depth, dental mobility, sulcus bleeding index clinical index changes. Results 1 month after treatment of gingival inflammation, periodontal abscess, overflow pus, teeth loose significant effect. Gingival sulcus hemorrhage index, periodontal index decreased significantly, while periodontal disease in periodontitis, periodontal abscess, wisdom teeth pericoronitis clinical efficacy was significant, clinical efficacy and effective rate was 97.2%. Conclusion Palio dentin minocycline hydrochloride ointment is the treatment of choice for the treatment of periodontal disease, can effectively inhibit periodontal plaque, inhibit the host reaction, its strong effect, not easy to produce resistance, and the side effects of small, it is worth In clinical application of promotion.