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目的：观测单侧输尿管梗阻家犬双肾内动脉血流动力变化，为诊断输尿管梗阻提供理论依据。方法：彩色多普勒超声对实验组８例单侧输尿管结扎家犬及８例正常对照家犬在术前及术后１～２０ｄ行双肾血流动力及实时超声观测，测定双肾内动脉阻力指数（ＲＩ）、搏动指数（ＰＩ），并与病理检查及肾盂压力结果对比。结果：ＲＩ与ＰＩ有高度相关性（ｒ＝０．９６７，Ｐ＜０．００１）；实验组梗阻肾ＲＩ值（≥０．５８）显著高于术前及对照组肾ＲＩ值（＜０．５８）（Ｐ＜０．００１）；实验组梗阻肾与对侧健肾ＲＩ差值（≥０．１）显著高于对照组双肾ＲＩ差值（＜０．１）（Ｐ＜０．００１）；实验组术后对侧健肾ＲＩ较对照组肾ＲＩ低（Ｐ＜０．００１）；ＲＩ与肾积水程度、肾盂压力无关；梗阻肾肾内动脉管壁增厚、管腔狭窄可能为ＲＩ升高的原因。结论：彩色多普勒超声观测输尿管梗阻肾肾内动脉血流动力改变，对诊断输尿管梗阻有重要意义。
OBJECTIVE: To observe the changes of hemodynamics in the bilateral renal arteries in dogs with unilateral ureteral obstruction and provide a theoretical basis for the diagnosis of ureteral obstruction. Methods: 8 cases of unilateral ureteral ligation in dogs and 8 normal control dogs in experimental group were examined by color Doppler ultrasonography before and 1 ~ 20 days after operation. The bilateral renal arteries Resistance index (RI), pulsatility index (PI), and compared with the pathological examination and pelvic pressure results. Results: RI and PI were highly correlated (r = 0.967, P <0.001). RI in the experimental group (≥0.58) was significantly higher than that in the preoperative and control groups (P <0.001) 58) (P <0.001). The RI difference (≥0.1) between obstructive kidney and contralateral kidney in experimental group was significantly higher than that in control group (<0.1) (P <0.001) ); RI of lateral kidney in experimental group was lower than that in control group (P <0.001); RI was not correlated with hydronephrosis and renal pelvic pressure; the renal wall of obstructed renal artery was thickened and stenosis was likely The reason for the RI increase. Conclusion: The color Doppler ultrasound observation of ureter obstruction renal artery and renal artery hemodynamic changes, diagnosis of ureteral obstruction has important significance.