Interferon相关论文
The majority of colorectal cancer patients are not responsive to immune checkpoint blockade (ICB).The interferon gamma (......
Host interferon-stimulated gene 20 (ISG20) exerts antiviral effects on viruses by degrading viral RNA or by enhancing IF......
Viruses depend on host cellular metabolism to provide the energy and biosynthetic building blocks required for their rep......
Objective: This study conducted a systematic review of randomized controlled trials in order to evaluate the efficacy an......
目的 对慢性乙型肝炎患者细胞毒T细胞内穿孔素(Perforin)?干扰素(IFN-γ)及白细胞介素10(IL-10)表达与病毒消除的关系进行研究分析......
目的 观察并分析小儿支气管肺炎患者联合应用沙丁胺醇与干扰素进行治疗的临床效果?方法 选取我院儿科收治的94 例支气管肺炎患儿为......
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For a virus,to inhibit host interferon(IFN)expression is indispensable for its proliferation,since IFN is crucial for ho......
STAT6 was a crucial role in lymphocyte differentiation and proliferation of adaptive immunity.Recently,it was investigat......
RIG-1 and MDA-5 signaling pathways contribute to IFN-β production and viral replication in Porcine c
Interferon(IFN)is known for its antiviral activity.However,it is surprising that treatment of IFN-α and IFN-β in vitro......
Encephalomyocarditis Virus 3C Protease Attenuates Type Ⅰ Interferon Production and Disrupts TANK Inh
TRAF family member-associated NF-κB activator (TANK) is a scaffold protein that assembles into the IRF3/7-phosphor-ylat......
Aim: To explore an optimal treatment for HBeAg positive chronic hepatitis B(CHB)with high HBV load.Methods: One hundred ......
Effect of Qiwei Baizhu Powder on the Related Elements Expression on TLR3 Signal Transduction Pathway
Objective:To investigate the effect of Qiwei Baizhu powder on the relatedsignaling molecules and inflammatory factors ex......
Effect of HLA-DP and IL28B gene polymorphisms on response to interferon treatment in HBeAg seroposit
Aim The reason why the majority of chronic hepatitis B (CHB) patients do not respond to conventional interferon α (IFN......
More than 350 million persons are suffering from hepatitis B virus (HBV) worldwide,and over one million people die each ......
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Predictors of response to antiviral therapy in patients with chronic hepatitis C from Pakistani popu
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轮状病毒(rotavirus，RV)是世界范围内引起婴幼儿和动物幼崽急性肠胃炎的主要病因之一。轮状病毒感染具有明显的种属特异性，病毒感染......
Why neurogenesis is attenuated in elderly individuals is an intriguing question that has raised renewed interest.Mechani......
Early Serum HBsAg Kinetics as Predictor of HBsAg Loss in Patients with HBeAg-Negative Chronic Hepati
Hepatitis B surface antigen(HBsAg)loss is an ideal treatment endpoint for patients with chronic hepatitis B(CHB).We inve......
DNA sensing and associated type 1 interferon signaling contributes to progression of radiation-induc
Liver damage upon exposure to ionizing radiation(IR),whether accidental or therapeutic,can contribute to liver dysfuncti......
Fludarabine inhibits type I interferon-induced expression of the SARS-CoV-2 receptor angiotensin-con
Angiotensin-converting enzyme 2(ACE2)is the receptor for severe acute respiratory syndrome coronavirus(SARS-CoV)and SARS......
Ocular surface squamous neoplasia resistant to topical interferon alpha 2b in a patient with follicu
Dear Editor,Treatment for ocular surface squamous neoplasia(OSSN)includes topical mitomycin C(MMC),5-fluorouracil(5-FU)a......
Conventional dendritic cells(cDCs)are categorized into two main subsets,cDC1 and cDC2,distinguished by their differentia......
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Interferon Regulatory Factor 5 and Renin-Angiotensin-Aldosterone System Polymorphisms in Coronary Ar
Heart diseases are the main cause of mortality in Mexico, being coronary </span><span style=\"font-family:Verdana;\"......
DDX19 Negatively Regulates Type I Interferon Signaling through Disrupting TBK1-IKKε-IRF3 Interaction
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More than 350 million persons are suffering from hepatitis B virus(HBV)worldwide,and over one million people die eac......
Precancerous lesion,a well-established histopathologically premalignant tissue with the highest risk for tumorigenes......
Cytosolic RNA/DNA sensing warns host cells both microbe invasion and cellular damage,and to initiate counter measure......
Interferon gamma (IFN-γ) belongs to the MHC Class I genes.One of the most important and striking feature of IFN-γ ......
The cyclin ECdk2p27Kip1 complex controls Myc activity and turnover at target promoters by regulating
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The interferon system in tree shrews (Tupaia belangeri) genomic sequence retrieval, molecular identi
The interferon (IFN) system constitutes the first line of host-defense against infections and other danger signals.As sh......
Genetic recoding by C6-deamination of adenosine(A)to produce inosine(I)in double-stranded(ds)RNA structures is an im......
To clarify the role of APOBEC3G (A3G) in cellular defense against hepatitis B virus ( HBV), the expression of A3G in nor......
Potential of G-CSF supplementation to counter the neutrophil effects of standard PEG-IFNα plus ribav
Objective To investigate the effects of the granulocyte colony stimulating factor (G-CSF) with pegylated interferon alph......
慢性丙型病毒性肝炎(chronic hepatitis C,CHC)是世界范围内最为严重的感染性疾病之一。据世界卫生组织统计,全球丙型肝炎病毒(hep......
AIM: To investigate the expression of tumor-antigens and major histocompatibility complex(MHC)-machinery components in g......
The Change of Quantitative of HBeAg Can Predict the Efficacy of Peg-IFN-α 2a in HBeAgpositive CHB Pa
Objective To investigate the quantitation of hepatitis B e antigen(HBeAg)at week 24 in predicting the efficacy of pegyla......
Hepatitis D virus(HDV) is a defective RNA virus which requires the help of hepatitis B virus(HBV) virus for its replicat......
Recipients of solid organ transplants(SOT) and stem cell transplants(SCT) constitute a group of patients at risk for tub......
Prediction of the Response to Pegylated Interferon α-2a in Patients with HBeAg Positive Chronic Hepa
Objective To assess on-treatment serum HBsAg and HBV DNA kinetics in HBeAg-positive CHB patients to predict the efficacy......
Interaction of IFNL3 with insulin resistance,steatosis and lipid metabolism in chronic hepatitis C v
Metabolic changes are inextricably linked to chronic hepatitis C(CHC).Recently polymorphisms in the IFNL3(IL28B)region h......
Direct-acting antiviral agents(DAAs)for hepatitis C virus(HCV)infection are one of the major advances in its medical tre......
