podocyte相关论文
目的:观察高胆红素血症对模型大鼠肾小球的影响，并探讨其量效反应及机制。方法:将24只成年雄性SD大鼠按随机数字表法分为4组，每组6只......
Objective: To identify the significance of autophagy in lupus nephritis(LN),we counted the number of autophagosomes in p......
tripterygium glycoside up-regulat autophagy to protect the podocyte injury induced by puromycin amin
Background:Tripterygium glycoside(TG),one of the active ingredients of Tripterygium wilfordii Hook F(TwHF),a widely used......
Background:In this study,we investigated the mechanism underlying the effects of the mTOR protein kinase inhibitor rapam......
This study tested the hypothesis that early diabetic podocyte injury is caused, in part, by up-regulation of transient r......
The Interleukin-6 Classic-and Trans-Signaling are Both Implicated in High Glucose induced Podocyte I
Background: Interleukin 6(IL-6)is a pleiotropic cytokine that has both pro-and anti-inflammatory properties via the memb......
Objective:To identify the significance of autophagy in lupus nephritis(LN),we counted the number of autophagosomesin pod......
tripterygium glycosideupregulateautophagy to protect the podocyte injuryinduced by puromycin aminonu
Background:Tripterygium glycoside(TG),one of the active ingredients of Tripterygium wilfordii Hook F(TwHF),a widely used......
Triptolide is often used to treat patients with immunoglobulin A nephropathy(IgAN),especially in Asia.However,its detail......
Background:Lupus nephritis(LN)is oneof the most common and severe complications in Systemic lupus erythematosuspatients,......
Supernatant of Mesangial Cell Cultured With AIgA1 from IgA Nephropathy Patients Inhibits Podocyte Au
IgA nephropathy(IgAN)represents the most frequent glomerulonephritis in the world.Although podocyte injury has been impl......
Diabetic nephropathy, a dominating cause of end stage renal disease as well as a lethal microvascular complication of di......
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Effects of mycophenolate mofetil, valsartan and their combined therapy on preventing podocyte loss i
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Caspase-11/4 and gasdermin D-mediated pyroptosis contributes to podocyte injury in mouse diabetic ne
Diabetic nephropathy(DN)is characterized by sterile inflammation with continuous injury and loss of renal inherent paren......
Background Hereditary renal tubular disease can cause hypercalciuria,acid-base imbalance,hypokalemia,hypomagnesemia,rick......
目的 探讨黄葵浸膏粉对高糖诱导下足细胞相关蛋白Nephrin和Podocin表达的影响及其在糖尿病肾病治疗中的作用机制.方法 以小鼠足细......
The role of B7-1 in podocyte injury has received increasing attention.The aim of this study was to investigate whether l......
特发性膜性肾病(IMN)的发病机制尚未完全阐释清楚.目前研究认为,IMN的发病与足细胞密切相关,在其免疫发病机制中,足细胞既是靶细胞......
在糖尿病条件下糖基化终末产物(AGEs)形成速率加快,引起足细胞损伤,进而参与糖尿病肾病(DN)的发生.AGEs形成于葡萄糖和蛋白的相互......
激素耐药型肾病综合征的治疗十分棘手,其发病机制尚未完全阐明.近年来,相关研究发现一些足细胞突变基因可能在激素耐药型肾病综合......
全反式维甲酸(ATRA)是维生素A类衍生物,在调节细胞聚集、分化、凋亡、增殖及炎症反应中起重要作用.近年来ATRA在肾脏疾病的作用,特......
瞬时受体电位阳离子通道蛋白6(TRPC6)是由 TRPC6 基因编码的瞬时受体超家族成员之一,在人体内各组织或器官广泛表达,在肾小球足细......
目的 观察人脐带间充质干细胞(hUCMSCs)对微小病变型肾病(MCN)大鼠蛋白尿及足细胞的作用,并探讨其可能的机制.方法 60只雄性SD大鼠......
Effect of Down-regulation of TRPC6 on the Puromycin Aminonucleoside-induced Apoptosis of Mouse Podoc
poptosis induced by PAN....
To investigate the protective effects of eplerenone on adriamycin-induced renal injury and the possible mechanisms invol......
目的 观察IgA肾病(IgAN)患者足细胞损伤的各种表现,探讨其与蛋白尿的关系.方法 收集35例伴有明显蛋白尿[尿蛋白量(24 h)>1.0 gl的I......
目的 观察活性维生素D(VitD)对足细胞钙敏感受体(CaSR)表达的影响,探讨其对足细胞保护作用的可能机制.方法 体外分化培养的小鼠永......
Tongluo Digui decoction(通络地龟汤)treats renal injury in diabetic rats by promoting autophagy of podocyt
OBJECTIVE:To investigate the effects of Tongluo Digui decoction on renal injury and streptozoto-cin-induced podocyte aut......
目的观察肾苏Ⅱ方对局灶节段性肾小球硬化(focal segmental glomerulosclerosis,FSGS)大鼠肾脏功能、病理、足细胞数量、Notch-P53......
目的观察不同浓度缬沙坦体外干预高糖环境下小鼠足细胞间充质细胞转分化及转化生长因子-β1(TGF-β)/Smad信号通路的调节作用。方......
,Changes in angiopoietin expression in glomeruli involved in glomerulosclerosis in rats with daunoru
Aim: To study the potential pathological role of endogenous angiopoietins in daunorubicin-induced progressive glomerulos......
,Curcumin attenuates high glucose-induced podocyte apoptosis by regulating functional connections be
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目的 探讨兔抗鼠Fx1A抗体诱导膜性肾病大鼠模型的方法及病理特点.方法 SD雄性大白鼠64只随机分为正常对照组(18只)、正常兔血清组(......
CD28/B7-1是一对参与机体特异性免疫应答极其重要作用的分子。CD28主要存在于T淋巴细胞表面，而B7-1为CD28的配体之一，可表达于肾脏足......
A Potential Pathological Role of Angiopoietins Expression in Glomeruli during Progressive Glomerulis
A potential pathological role of angiopoietins (Ang) in glomeruli following podocyte injury-induced progressive glomerul......
Endoplasmic reticulum stress is involved in podocyte apoptosis induced by saturated fatty acid palmi
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目的：观察阿米洛利在经典的5/6肾切除大鼠模型中对蛋白尿的影响，探讨其影响蛋白尿的机制。方法构建经典的5/6肾切除大鼠模型，实验分为......
目的探讨线粒体分裂-动力相关蛋白1(Drp1)及其抑制剂Mdivi-1在醛固酮肾损伤小鼠足细胞中的作用及可能机制。方法 20只小鼠随机均分......
Assessment value of serum 25-hydroxy-vitamin D content detection for patients with diabetic nephropa
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 探讨降脂药辛伐他汀及血管紧张素Ⅱ受体拮抗剂类药物缬沙坦对早期糖尿病肾病大鼠肾脏的保护作用.方法 用链脲佐菌素(STZ)诱导......
糖尿病肾病(DN)的发病机制未完全明了,近年来发现DN的发病与炎性反应、缓激肽减少、足细胞损伤及microRNA等有关.由于DN的发病机制......
目的 研究高脂诱导的大鼠肾小球足细胞损害及肾组织整合素连接激酶(ILK)的表达.方法 36只Wistar大鼠分3组:高脂饮食组给予高脂饲料......
目的 观察不同浓度非诺贝特对高糖培养的足细胞的影响,探讨糖尿病肾病(DN)的早期机制. 方法 分离收集大鼠肾小球并进行足细胞原代......
局灶节段性肾小球硬化(FSGS)由多种病因引起,临床主要以大量蛋白尿及肾病综合征为主要表现,病理表现为肾小球局灶节段性硬化.患者......
