Simvastatin相关论文
Simvastatin Improves Outcomes of Endotoxin-induced Coagulopathy by Regulating Intestinal Microenviro
Objective:The systemic inflammatory response is regarded as the major cause of endotoxin-induced coagulopathy,which is a......
目的 分析比索洛尔联合辛伐他汀治疗老年不稳定心绞痛的临床效果。方法 从2017年9月至2018年9月到我院进行治疗的不稳定性心绞痛患......
目的:探讨缺氧条件下辛伐他汀(Sim)对体外培养的人视网膜色素上皮(RPE-19)细胞的影响及其可能机制.方法:将体外培养的人RPE-19细胞......
Drug-associated reward memories are conducive to intense craving and often trigger relapse.Simvastatin has been shown to......
Ilexgenin A enhances the effects of simvastatin on non-alcoholic fatty liver disease without changes
Cardiovascular disease (CVD) is the most common cause of death in patients with non-alcoholic fatty liver disease (NAFLD......
Multifunctional simvastatin-loaded porous hydroxyapatite microspheres/collagen composite scaffold fo
The multifunctional composite scaffolds with both excellent angiogenic and osteogenic activities are highly desirable to......
Bioactive scaffolds-based tissue engineering is a promising strategy for repairing cranial defects[1].How to impart the ......
Osteoporosis is a systemic and metabolic skeleton disease.It is urgent to develop the new drugs with good curative effec......
Intraosseous Injection of Simvastatin/Poloxamer 407 Hydrogel Improves Pedicle Screws Fixation in Ova
Background:Osteoporosis leads to poor osseointegration and reduction in implant stability.Statins have been found to sti......
Intraosseous Injection of Simvastatin/Poloxamer 407 Hydrogel Improves Pedicle Screws Fixation in Ova
Background:Osteoporosis leads to poor osseointegration and reduction in implant stability....
InjectableSimvastatinHydrogelPromotesPETArtificialGraft-BoneHealingOnRabbitACLReconstruct
Introduction:ToprepareaPEG–PLGAcopolymershydrogelloadedwithsimvastatinreleasesystem.Investigateitspotentialon polyethyl......
EffectsofSimvastatinandCombinationofSimvastatinandNylestriolonBoneMetabolisminOvariecto
Weaimtocomparetheeffectsofsimvastatinandcombinationofsimvastatinandnylestriolonbonemetabolismin ovariectomized(OVX)rats.......
Simvastatin Alleviated Airway Inflammation and Airway Remodeling through the Upregulation of Autopha
目的 Statins have been widely used ininflammatory diseases including asthma,because of their anti-inflammatory and immun......
Objective: To assess the effects of simvastatin on the ex vivo differentiation and proliferation of human mesenchymal st......
Objective To study the effects of simvastatin on the serum-induced hypertrophy of cultured rat cardiomyocytes, and to in......
Aim: To investigate the protective effect and the mechanism of simvastatin on myocardial injury caused by diabetes with ......
Aim: To assess the bioequivalence of two simvastatin tablet formulations in 24 male healthy volunteers.Methods: The stud......
Effects of CYP3A4*1G, CYP3AP1*3 and gender on pharmacokinetics of simvastatin and simvastatin acid i
Aim: To study effects of CYP3A4*1G (G＞A), CYP3AP1*3 (G＞A) and gender on pharmacokinetics of simvastatin and simvastatin ac......
Single-step bioproduction of the simvastatin precursor monacolin J in an industrial strain of Asperg
Monacolin J is a key precursor for the synthesis of simvastatin(Zocor),an important drug for treating hypercholesterolem......
Simvastatin protects cerebral microvascular endothelial cells through decreasing HMGB-1 release in h
Objective: Cerebrovascular disease (CVD) is a cerebral dysfunction caused by a variety of vascular encephalopathy,diabet......
目的：辛伐他汀(Simvastatin,SIM)属于3-羟基-3 甲基戊二酰辅酶A 还原酶抑制剂,能提高骨密度,促进成骨。辛伐他汀促进种植体周围成骨......
会议
Maltodextrin based polymeric micelle composite injectable hydrogels for controlledsimvastatinrelease
As a kind of artificial extracellular matrix materials,injectable hydrogelshave been widely used as carrier materials fo......
Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxife
Background: Acquired tamoxifen resistance(TamR)remains a major challenge in breast cancer endocrine therapy.The mechanis......
Cell Homing Strategy For Bone Tissue Engineering Based on the Cooperative Actions of Simvastatin and
Purpose: The purpose of this study was to investigate the cooperative effects of simvastatin(SIM)and stromal cell derive......
Simvastatin is a typical lipid lowering agent and often detected in aquatic environments,and the potential adverse effec......
目的 浅析他汀类药与其他药物联用时不良反应的特点及合理用药措施。方法 采集100例2018年5月至2019年8月在本院联合用药治疗后出......
目的 研究分析常规剂量、短疗程辛伐他汀对老年2型糖尿病（T2DM）患者血脂、C反应蛋白（CRP）的影响与临床意义。方法 120例LDL-C≥2.6mmol......
Objective To compare the effects of Xuezhikang and Simvastatin in patients with primary hyperlipidemia. Methods 108 pa......
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Effects of simvastatin on cigarette smoke extract induced tissue-type plasminogen activator and plas
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Intensive cholesterol lowering with statin improves the outcomes of percutaneous coronary interventi
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Cardioprotective effects of simvastatin on reversing electrical remodeling induced by myocardial isc
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Effect of simvastatin on the expression of farnesoid X receptor in diabetic animal models of altered
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目的 探讨辛伐他汀对结肠癌裸鼠移植瘤血管生成的影响.方法 以人结肠癌colo-320细胞注入12只雌性裸鼠皮下建立移植瘤模型,随机分为......
目的探讨辛伐他汀不同剂量应用于缺血性脑血管病患者对脑血管储备能力(CVR)的影响。方法选取2011年3月至2013年8月收治的缺血性脑......
小剂量Ｓｉｍｖａｓｔａｔｉｎ治疗慢性肾衰高脂血症临床观察第二附属医院肾内科李军，朱笑萍，刘映红，罗季安，成梅初关键词肾功能衰竭，慢性；Ｓｉｍｖａｓｔａｔｉｎ；血脂过多；治疗应用近年......
多危险因素干预实验资料研究表明,糖尿病病人冠心病发生的主要危险因素与非糖尿病病人一样是高胆固醇血症、吸烟和舒张压的增高,......
近年研究证明抑制胆固醇合成的调速酶(3-羟-3甲基戊二酰辅酶 A 还原酶,简称 HMG CoA 还原酶)对治疗原发性高胆固醇血症和糖尿病引......
3羟－3甲基成二酸辅酶A还原酶抑制剂（HMG－COA）是降LDL－胆固醇（LDL－C）最有效的药物。氟伐他汀（fluvastatin）为其中最新，也是第一个能完全合成的......
目的建立测定辛伐他汀及其有关物质洛伐他汀的含量的反相高效液相色谱方法。方法采用Symmetry C18(250 mm×4.6 mm,5μm)色谱柱,流......
舒降之,又名辛伐他汀(simvastatin),新近国外研究证实,它能有效调节异常血脂,减少冠心病人心血管事件的发生率和死亡率,但国内报......
我院干部病房自1995年9月至1996年3月应用舒降之(Simvastatin)治疗老年性高脂血症50例,取得了较满意的效果,现将结果报道如下。 ......
In vitro and in vivo cytochrome P450 3A enzyme inhibition by Aframomum melengueta and Dennettia trip
Objective: To evaluate the in vitro and in vivo inhibitory effects of two commonly used herbs, Aframomum melengueta(A. m......
Objective: To observe the effects of red yeast rice(RYR) on blood lipid levels, aortic atherosclerosis(AS), and plaque s......
Protective Effects of Xiongshao Capsule(芎芍胶囊) on Anti-inflammatory Function of High-Density Lipoprot
Objective: To observe the effects of Xiongshao Capsule(芎芍胶囊, XSC) on anti-inflammatory properties of high-density li......
随着饮食结构的变化，高脂血症的发病率逐渐增加，其中，高甘油三酯血症合并脂肪肝更随之增加。因此，本文对合并脂肪肝的高脂血症病人，在饮......
The effect of simvastatin on bone mineral density and bone turnover of diabetic osteoporosis patient
INTRODUCTIONManybasicandclinicalexperimentsshowedthatdrugsofstatinsmightstimulateproliferationanddifferentiationofosteob......
