forkhead相关论文
卵巢癌缺少早期诊断方法,而晚期患者通过肿瘤细胞减灭术和基础化疗等传统治疗方案后易复发,因此从卵巢癌发生发展的分子机制探索新......
Objective To investigate the apoptosis-inducing effect of endogenous nitric oxide (NO) suppression in gastric cancer cel......
Objective The forkhead transcription factor FOXP3 is a key molecular which can mediate regulatory T cells immune-related......
Objective Parkinson’s disease(PD),a neurodegenerative disorder,has been reported to be associated with brain neuroinfla......
叉头状/翼状螺旋转录因子3(forkhead or winged helix transcription,FOXP3)是叉头家族成员之一,特异地表达于CD4+CD25+Treg(regul......
The transcription factor forkhead box protein A2(FOXA2, also known as hepatocyte nuclear factor 3β or transcription fac......
Free fatty acids are known to play a key role in promoting loss of insulin sensitivity in type 2 diabetes mellitus but t......
目的观察转录因子Foxp3(forkhead box protein P3)在原发性干燥综合征患者(primary Sjgren’s syndrome,pSS)外周血和唇腺中的表......
Currently,60 million women of reproductive age(18-44 years old) worldwide,and approximately 3 million American women hav......
FOX(forkhead box)是脊椎动物叉头样转录因子的总称,是一个具有多种功能的转录因子大家族,通常和细胞生长发育的调控有关[1].FOXP3......
Foxc(forkhead box C)基因在人、鼠等多个物种间高度保守,其亚家族成员Foxc1基因和Foxc2基因参与了细胞内多条重要信号转导通路,与......
AIM:To investigate the dysfunction of the immunological barrier of the intestinal mucosa during endotox-emia and to eluc......
AIM:To study whether immune-activation stage in serum of adult Crohn’s disease (CD) patients correlates with disease ac......
AIM: To assess the anti-inflammatory effect of the probiotic Bifidobacterium lactis (B. lactis) in an adoptive transfer ......
High mobility group box-1 protein inhibits regulatory T cell immune activity in liver failure in pat
BACKGROUND:Liver failure in chronic hepatitis B(CHB) patients is a severe,life-threatening condition.Intestinal endotoxe......
CD4 T helper(Th) cell differentiation into distinct T cell subsets is critical to the normal function of the immune syst......
Ribavirin contributes to eradicate hepatitis C virus through polarization of T helper 1/2 cell balan
The mechanism of action of ribavirin(RBV) as an immunomodulatory and antiviral agent and its clinical significance in th......
Objective:Foxp3,the main regulator of Treg (regulatory T) cells, is down-regulated in breast carcinoma and other cancers......
Foxm1基因是Fox蛋白家族的一个亚型,参与调控肿瘤细胞的增殖、凋亡、浸润与侵袭等。近年来研究发现它在胃癌中存在过高表达并对胃......
目的 :探讨miR-30a在人乳腺癌细胞系中的表达,及其对乳腺癌细胞系增殖、迁移和侵袭的影响,并寻找作用靶基因。方法:用q RT-PCR法检......
Objective:To establish a stable and high efficient method for collection of CD4+CD25+ regulatory T cells from rats in vi......
The homeostasis of the immune system depends on the balance between the immune response to an invaded pathogen and the i......
目的观察高迁移率族蛋白B1(high mobility group box-1 protein,HMGB1)对调节性T细胞(regulatory Tcell,Treg)叉头翼状螺旋转录因......
长期以来,由于缺乏确切的细胞表面标志和发挥抑制作用的分子基础,免疫学家对体内是否存在以抑制自身T细胞活化等免疫反应为主要功......
PTEN基因是目前发现的第一个具磷酸酶活性的抑癌基因,与数种具肿瘤倾向的遗传性疾病及多种散发性肿瘤有关。PTEN能特异性地使磷脂......
Forkhead蛋白是一类在进化上高度保守的重要转录因子家族。目前,已经发现超过100种编码Forkhead蛋白的基因,Forkhead蛋白的典型结......
Effects of Shen-Fu Injection (参附注射液) on Apoptosis of Regulatory T Lymphocytes in Spleen during Post-
Objective: To investigate whether Shen-Fu Injection(参附注射液, SFI) reduces post-resuscitation immune dysfunction in a ......
AIM: To show the efficient generation of hepatocytelike cells(HLCs) differentiated from the induced pluripotent stem cel......
Aim:To investigate the apoptosis-inducing effect of oridonin,a diterpenoid iso-lated from Rabdosia rubescens,in the hum......
皮质脊髓投射神经细胞(cortico-spinal projection neurons,CSPN)对于大脑的功能非常重要,但目前还缺乏研究小鼠发育期CSPN基因表......
目的研究广西巴马地区居民血清中叉头框蛋白O3A(forkhead box protein O3A,FOXO3A)基因mRNA及蛋白表达水平的差异,探讨其与家庭聚......
先天性睑裂狭小综合征,即睑裂狭小-上睑下垂-逆向内眦赘皮综合征(Blepharophimosis-ptosis-epicanthus inversus syndrome,BPES)为......
Checkpoint with forkhead-associated and ring finger promoter hypermethylation correlates with micros
AIM:To examine the methylation status of the promoter region of the checkpoint with forkhead-associated and ring fi nger......
AIM: To study the biological and clinical characteristics of transcription factor forkhead box protein 3 (FOXP3) in hepa......
AIM: To investigate whether the 7-difluoromethoxyl-5, 4’-di-n-octylgenistein (DFOG), a novel synthetic genistein analog......
AIM:To investigate the expression of B7-H1 in human colorectal carcinoma (CRC) to define its regulating effects on T cel......
叉头转录因子O亚型(forkhead box O,FoxO)3a是FoxO家族一员,具有抑癌基因的作用,调控多种肿瘤的发生发展,包括乳腺癌、前列腺癌、......
Remarkably Reduced Expression of FoxO3a in Metaplastic Colorectum, Primary Colorectal Cancer and Liv
The forkhead family members of transcription factors (FoxOs) are expected to be potential cancer-related drug targets an......
目的:构建人FOXQ1(homo sapiens forkhead box Q1)基因真核表达载体pAcGFP1-N1-FOXQ1,并在大肠癌细胞系Colo-320中瞬时表达.方法:......
Hepatocellular carcinoma(HCC)and pancreatic cancer remain difficult to treat,and despite the ongoing development of new ......
Objective:To screen the proteins interacting with the Treg specification factor forkhead box protein P3 (FOXP3) by yeast......
叉头框C2是属于forkhead或winged helix家族“C”亚族的一个转录因子.目前,对FOXC2基因功能的研究主要集中在FOXC2基因表达以及突......
转录因子叉头框Q1(forkhead box Q1,FOXQ1)是叉头框(forkhead box,FOX)超家族的成员之一,广泛存在于人体的多种组织和器官,参与胚......
FoxM1 overexpression promotes epithelial-mesenchymal transition and metastasis of hepatocellular car
AIM: To investigate the expression of forkhead box protein M1(Fox M1) in the process of epithelial mesenchymal transitio......
叉头框蛋白M1(forkhead box M1,Fox M1)属于Fox转录因子家族,在多种恶性肿瘤中异常高表达,与多个癌基因信号通路相关,在肿瘤的发生......
