A series of 6-fluoro-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline-2-carboxamide derivatives was designed based on the......

Two novel iV-heterocycle-containing benzotriazole compounds,5-(5-chloro-2-benzotriazolyl)-6-hydroxy-l,4-dimethyl-3-car-b......

A facile synthesis of suvorexant,an orexin receptor antagonist,is described.The key intermediate 6 was prepared from R-3......

Linear triblock copolymers of poly(N-isopropylacrylamide) (PNIPAM) and poly(ethylene glycol) (PEG) with two azide groups......

Macrocyclic tri- and tetra-amines containing a hydroxyl group in the ring have been prepared in moderate yields by a 1:......

在有盐酸存在的情况下，利用邻氨基苯甲醇和硫脲反应合成2-亚氨基-四氢-3，1-苯并噻嗪，并对反应机理进行了分析．此外，利用傅立叶红外光谱......

含1，2，4-三嗪结构的化合物具有抗病毒、调节植物生长等作用。本文用α-叔戊酰基硫代甲酰取代苯胺缩氨基脲环化得到4-取代苯基-6．叔丁......

从γ-丁内酯出发经开环、环合、水解三步反应合成得到环丙烷甲酸（总收率77．6％）。对γ-氯代丁酸酯环合一步反应进行改进，用廉价的Na2CO3......

以二苯甲胺、环氧氯丙烷为起始原料,经开环、环合、甲磺酰化、氰基取代再水解,催化氢化还原共5步反应的新路线简化了含氮杂环化合......