SMEDDS相关论文
Objectives: The objective of this investigation was to optimize an effective SMEDDS formulation for Rh1 to improve its i......
Application of nanobiotechnology to deliver therapeutic drugs selectively to diseased sites with imp
A number of drugs only give rise to limited clinical response when causing remarkable toxicities due to wide distributio......
Self-microemulsifying drug delivery systems(SMEDDSs)have recently returned to the lime-light of academia and industry du......
目的探讨SMEDDS对靛玉红口服给药生物利用度的影响。方法采用单剂量灌胃给药进行大鼠体内药代动力学试验,利用HPLC检测大鼠全血中......
索拉非尼(Somfenib)是一种新型抗肿瘤药物,但其在水中难溶,生物利用度低.为了增加索拉非尼的生物利用度,本研究制备了索拉非尼自微......
葫芦素B临床应用于肝炎和原发性肝癌的治疗。本文以难溶性药物葫芦素B为模型药物，以微乳为载体，研究制备葫芦素B注射用自乳化微乳制......
,Self-microemulsifying drug delivery system for improving the bioavailability of huperzine A by lymp
Huperzine A (Hup-A) is a poorly water-soluble drug with low oral bioavailability.A self-microemulsifying drug delivery s......
该研究主要进行了以下几方面的工作:1.在原有处方的基础上,对口服胰岛素胶囊的内容物—自微乳传输系统(SMEDDS)进行了处方优化,使......
目的考察松萝酸原料及自微乳的抗菌抗炎作用。方法采用体外抑菌实验观察松萝酸原料及自微乳的抑菌效果；采用MTT法考察松萝酸原料及......
靛玉红(Indirubin)为青黛等中药的有效成分,具有抗炎、抗肿瘤等作用,临床用于治疗慢性粒细胞白血病(CML)。但因口服生物利用度低、......
Effect of ionization of drug on drug solubilization in SMEDDS prepared using Capmul MCM and caprylic
The purpose of this study was to investigate the effect of ionization of drug on drug solubilization in SMEDDS(self-micr......
February 2017Elsevier would like to bring to your attention a pagination gap in Volume/Issue 12/1.Unfortunately,there is......
Preparation and characterization of solidified SMEDDS containing flurbiprofen by spray drying method
Flurbiprofen, a non-steroidal anti-inflammatory agent, is used to treat rheumatoid arthritis and sore throat (1)However,......
<正>设计制备了5种水难溶性药物(维生素A、维生素K2、辅酶Q10、槲皮素和反式白藜芦醇)的自微乳化给药系统（SMEDDS）,也称微乳预浓缩物......
综述了近年SMEDDS在中药制剂中的应用研究进展情况,认为SMEDDS在中药制剂研究中已经得到了普遍的关注和应用,已经取得了一定的研究......
水飞蓟素（silymarin，SM）是从水飞蓟（Silybum marianum（L．）Gaertner．）果实中提取分离得到的黄酮类有效成分，由水飞蓟宾（silybin）、水飞蓟宁（silid......
自乳化释药系统(Self－emulsifying drug delivery system,SEDDS)系油相、乳化剂、潜溶剂组成的固体或液体系统,一般分装于软或硬胶......
