SIGNALING相关论文
30. Knockdown of IGF-IR by Antisense Oligodeoxynucleotide auguments the sensitivity of bladder cance
AND AIM: Transitional cell carcinoma (TCC) of the bladder represents the fifth most prevalent malignancy in Western popu......
Plant hormone cytokinin signals through histidine-aspartic acid(H-D)phosphorelay to regulate plant growth and developmen......
Background:This study investigated the protective effects of L. reuteri ZJ617 on intestinal and liver injury and the und......
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The Plasma Membrane Protein PREN is a Potential Receptor Candidate of Fungal Elicitor PeaT1 which In
Protein elicitor PeaT1, which was originally isolated from Alternaria tenuissima, could induce systemic acquired resista......
How to optimization and improve the coverage and quality of the highway communication network has always been a signific......
Effects of DHEA on Human Marrow Stromal Cells: Role of Vitamin D Metabolism 1α-Hydroxylase/CYP27B1 i
With aging, there is a decline in bone mass and in osteoblast differentiation of human mesenchymal stem cells (hMSCs) in......
The Sucrose Transporter SUT4 Interacts with HXK1 and FUSCA3 respectively to Regulate Seed Germinatio
SUT4 is a kind of sucrose transporter located in the vacuole membrane, it has been confirmed that SUT4 interacts with Cy......
Extracellular proteins are vital for cell activities, including cell migration.Calumenin is highly conserved among eukar......
Somatic mutation and altered protein expression patterns cause inappropriate activation and deactivation of key players ......
Proteomic discovery of H2O2 response in roots and functional characterization of PutGLP gene from al
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Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a recently discoverednegative regulator of multiple gr......
Multifaceted roles of Arabidopsis PP6 phosphatase in regulating hormone signaling and plant developm
Reversible protein phosphorylation catalyzed by kinases and phosphatases is a major form of posttranslational regulation......
Neural inhibition in the brain is mainly mediated by onotropic GABA type A receptors.Apart from the GABA type receptors,......
Numerous studies have indicated oxidative stress as a key pathological factor in ischemic brain injury.One of the key li......
Ovarian cancer is the prime cause of death from gynecological malignancies in European and North American women. However......
Sex-determining Region of Y Chromosome-related High-mobility-group Box 2 in Malignant Tumors: Curren
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OBJECTIVE To identify the inhibitory effect of ursolic acid on the colorectal cancer HCT116 cells in vitro and in vivo,a......
OBJECTIVE To investigate the effect of scutellarin on the apoptosis of human colorectal cancer cells via the Hippo signa......
Inhibitory action of berberine on colorectal cancer HCT116 cells by regulation of Hedgehog signaling
OBJECTIVE To investigate the inhibition and mechanism of berberine on human colorectal cancer HCT116 cells through canon......
OBJECTIVE To investigate the pharmacological effect of ursolic acid(UA)on colitis-associated colorectal cancer(CAC)and i......
Suppression of AOM/DSS-induced colorectal cancer by scutellarin through downregulation of Wnt signal
OBJECTIVE To investigate the therapeutic effect of scutellarin on colitis-associated cancer(CAC)and its underlying mecha......
Giant cell arteritis(GCA)is a commonly occurring large vacuities characterized by angiopathy of medium and large-sized v......
Renal gluconeogenesis is one of the major pathways for endogenous glucose production.Impairment in this process may cont......
Hepatocellular carcinoma(HCC)is one of the most common malignant tumors in clinical practice.The pathogenesis of HCC is ......
Neuritin is a member of the neurotrophic factor family,which plays an important role in the promotion and development of......
BACKGROUND Pancreatic cancer is a highly malignant tumor of the gastrointestinal system whose emerging resistance to che......
Carvacrol Promotes Cell Cycle Arrest and Apoptosis through PI3K/AKT Signaling Pathway in MCF-7 Breas
Objective:To examine the role of carvacrol in modulating PI3 K/AKT signaling involved in human breast cancer pathogenesi......
DET1-mediated COP1 regulation avoids HY5 activity over second-site gene targets to tune plant photom
DE-ETIOLATED 1(DET1)and CONSTITUTIVE PHOTOMORPHOGENESIS 1(COP1)are two essential repressors of Arabidopsis photomorphoge......
Upregulation of the PPAR signaling pathway and accumulation of lipids are related to the morphologic
Goldfish comprise around 300 different strains with drastically altered and aesthetical morphologies making them suitabl......
Male sexual signaling and expected effects of hatchery-induced sperm competition vary with water dep
Salmonids like whitefish(Coregonus spp.)are often propagated in supportive breeding.Spawners are caught from their spawn......
An oncolytic adenovirus delivering TSLC1 inhibits Wnt signaling pathway and tumor growth in SMMC-772
Tumor suppressor in lung cancer-1(TSLC1)was first identified as a tumor suppressor for lung cancer,and frequently downre......
Dasatinib inhibits proliferation of liver cancer cells,but activation of Akt/mTOR compromises dasati
Dasatinib is a multi-target protein tyrosine kinase inhibitor.Due to its potent inhibition of Src,Abl,the platelet-deriv......
During virus infection,RIG-I-like receptors(RLRs)recognize viral RNAs and recruit the adaptor protein VISA to activate d......
A high-resolution cell atlas of the domestic pig lung and an online platform for exploring lung sing
The genetically engineered pig is regarded as an optimal source of organ transplantation for humans and an excellent mod......
Ufl1 deficiency causes kidney atrophy associated with disruption of endoplasmic reticulum homeostasi
The UFMylation modification is a novel ubiquitin-like conjugation system,consisting of UBA5(E1),UFC1(E2),UFL1(E3),and th......
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Ethylene as a gas phytohormone plays significant roles in the whole life cycle of plant,ranging from growth and deve......
O-GlcNAc,a monosaccharide derived from glucose,cycles on and off thousands of nucleocytoplasmic proteins and has ext......
The human glucagon receptor(GCGR)belongs to the class B G protein-coupled receptor(GPCR)family and plays a key role ......
The G-Protein-Coupled Receptors Transmit 20-hydroxyecdysone Signaling on the Cell Membrane to the Nu
Animal steroid hormones are conventionally known to initiate signaling via a genomic pathway by binding to the nucle......
Macroautophagy is a catabolic pathway that targets large, long-lived structures such as protein aggregates, damaged ......
Molecular identification and functional analysis of ethylene receptor regulators in Arabidopsis thal
As a gas hormone ethylene directly regulates plant growth and development, fruit ripening, organ senescence and the ......
We know ambient CO2 is continuing rising and this rising CO2 causes plants stomatal pores closing and thus regulates......
Regulation of ABA signaling and biosynthesis by OsbZIP23 that targets diverse drought resistance rel
The OsbZIP23 transcription factor,a close homolog of Arabidopsis ABI5,has been characterized for its essential role ......
Comprehensive Analysis of Autophagy-related Genes Genome-wide Identified in Tobacco Suggests a Centr
Autophagy is an evolutionarily conserved mechanism in both animals and plants,which has been shown to be involved in......
Spinal IL-33ST2 signaling contributes to the pathogenesis of neuropathic pain through astroglial JAK
Interleukin (IL)-33, a novel member of IL-1 family, has attracted growing interest since its discovery in 2003.In our pr......
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miR-146a-5p affects inflammation response of trophoblast by inhibiting TRAF6/NF-кB signaling pathway
Objective:To investigate the association of Micro-rna(miR)-146a-5p expression with preeclampsia,and further explore the ......
