scRNA-seq相关论文
近年来单细胞转录组测序技术（scRNA-seq）快速发展,相关生物信息学方法也应运而生。这些处理和分析方法能以单细胞分辨率来分析细胞群......
单细胞RNA测序数据分辨率的提高和不断增长的数据集带来了令人兴奋的机会。聚类分析是研究分析这些庞大的单细胞数据异质性的有利......
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单细胞RNA测序（Single-cell RNA-seq,scRNA-seq）能够测定数万、数十万个细胞所组成的样本中每个细胞的转录组状态,通过分析细胞之间......
呼伦贝尔草原短尾羊是由国家农业部认定的内蒙古的地方肉羊品种,因其尾短、产肉性能好、瘦肉率高等特点成为牧民养殖绵羊的良好选......
Neural stem cells(NSCs)in the spinal cord hold great potential for repair after spinal cord injury(SCI).The ependyma in ......
Single-cell RNA-seq and chromatin accessibility profiling decipher the heterogeneity of mouse γδ T c
The distinct characteristics of γδ T cells determine their vital roles in the formation of local immune responses and ......
Background:Spermatogenesis is the process by which male gametes are formed from spermatogonial stem cells and it is esse......
Mapping Human Pluripotent Stem Cell-derived Erythroid Differentiation by Single-cell Transcriptome A
There is an imbalance between the supply and demand of functional red blood cells (RBCs) in clinical appli-cations. This......
Development of thoracolumbar vertebra (TLV) and rib primordium (RP) is a common evolutionary feature across vertebrates,......
Annotating cell types is a critical step in single-cell RNA sequencing (scRNA-seq) data analysis.Some supervised or semi......
意大利蜜蜂是重要的经济昆虫,它们独特的级型分化现象和劳动分工机制一直是研究的热点。蜜蜂这些独特的行为,使得它们成为研究昆虫......
A high-resolution cell atlas of the domestic pig lung and an online platform for exploring lung sing
The genetically engineered pig is regarded as an optimal source of organ transplantation for humans and an excellent mod......
A high-resolution cell atlas of the domestic pig lung and an online platform for exploring lung sing
The genetically engineered pig is regarded as an optimal source of organ transplantation for humans and an excellent mod......
Dispen-Seq: a single-microparticle dispenser based strategy towards flexible cell barcoding for sing
Single-cell RNA sequencing (scRNA-seq) has become one of the most powerful tools to understand the heterogeneity of biol......
,Analysis of alternative cleavage and polyadenylation in mature and differentiating neurons using RN
Background:Most eukaryotic protein-coding genes exhibit altative cleavage and polyadenylation (APA),resulting in mRNA is......
Cells of eukaryotic multicellular organisms have inherent heterogeneity.Recent advances in single-cell gene expression s......
正则化是scRNA-seq数据分析的核心并影响决定下游分析的质量.相比bulkRNA-seq,由于scRNA-seq的zero inflation,其正则化是一个尚未......
癌症因其克隆异质性和组成复杂性一直是人类难以攻克的挑战。肿瘤由癌细胞和多种非癌细胞类型形成,它们与细胞外基质一起形成了肿......
CRISPR/Cas系统是细菌和古生菌的自适应免疫系统,其对基因组高效精准的编辑,极大地推动了发育生物学、表观遗传学、药物开发、疾病......
