Nox4相关论文
背景：研究发现，芒柄花素具有抗氧化、抗炎和免疫调节等生物活性。然而，芒柄花素是否具有调节葡萄糖氧化酶诱导大鼠肝星状细胞氧化应激......
第一部分淫羊藿苷ICA对RANKL诱导下RAW264.7细胞向破骨细胞分化过程的ROS的影响及破骨细胞形成的影响目的:通过测定RANKL诱导RAW26......
目的 探讨槲皮素对肺纤维化大鼠肺组织细胞间质转化、炎症及对NOX4-P62信号途径的影响，为进一步阐明槲皮素对肺纤维化的作用机制提......
第一部分Nox4在草酸钙结石患者肾乳头中的表达及其机制的初步探究【目的】探讨烟酰胺腺嘌呤二核苷酸磷酸氧化酶亚单位4（Nox4）在草酸......
研究目的随着年龄的增长和体内雌激素水平的下降,机体氧化-抗氧化系统失衡诱发氧化应激反应增加,导致骨量丢失和骨折风险增加。中......
探讨甲基丁香酚对缺氧/复氧(hypoxia/reoxygenation,H/R)致人肾小管上皮细胞HK-2损伤的影响及机制.通过细胞计数试剂盒(cell count......
背景：研究表明，应激状态下小鼠心肌、骨骼肌、肾脏及脑组织NOX蛋白过度上调，而NOX介导氧化应激在过量饮酒导致的酒精性肝损伤中的作用......
Idiopathic pulmonary fibrosis (IPF) is an aging-associated disease with a poor prognosis.Emerging evidence has revealed ......
目的通过检测炎症、氧化应激和细胞凋亡等神经损伤相关基因的表达,检测铁死亡信号通路相关蛋白的表达,从而探讨电针治疗慢性脑低灌......
骨形成蛋白和激活素的跨膜蛋白抑制因子（BMP and Activin Membrane-Bound Inhibitor,BAMBI）是一种跨膜糖蛋白,因其胞内结构与TGFβ家......
目的:NADPH oxidase 4（NOX4）,是体内产生活性氧（reactive oxygen species,ROS）的一个重要来源。目前,不断有研究发现NOX4涉及肿瘤发生......
目的:观察CCl4诱导的大鼠肝纤维化形成过程中肝组织中还原型烟酰胺腺嘌呤二核苷酸磷酸氧化酶4（NOX4）及核因子E2相关因子2（Nrf2）表达的......
ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and
Ferroptotic cell death is characterized by iron-dependent lipid peroxidation that is initiated by ferrous iron and H2O2 ......
Angiotensin-(1-7) improves cigarette smoking-related pulmonary fibrosis via attenuating the impaired
目的 To investigate the effect of Ang(1-7) on smoking-related lung fibrosis by the regulation of autophagy and ROS. 方法......
Inhibition of Notch signaling leads to increased intracellular ROS by upregulating Nox4 expression i
The essential roles of Notch pathway in angiogenesis have been reported for years.However, how Notch pathway plays its r......
目的 探究血管紧张素(1-7)如何通过调控活性氧(ROS)及自噬,以及对大鼠吸烟相关性肺纤维化的影响。方法 在体内动物实验方面,wistar......
会议
Aims: Apelin is the endogenous ligand for the G protein coupled receptor APJ.It promotes vascular smooth muscle cell pro......
目的 观察吡非尼酮对老年慢性阻塞性肺病合并肺间质纤维化患者NOX4、TGF-β1表达的影响,旨在探讨吡非尼酮治疗肺间质纤维化的作用......
Mutant Kras-and p16-Regulated NOX4 Activation Overcomes Metabolic Checkpoints in Development of Panc
Background: Kras activation and p16 inactivation are required for development of pancreatic ductal adenocarcinoma(PDAC).......
NADPH Oxidase 4 regulates anoikis resistance of gastric cancer through reactive oxygen species gener
Objective Gastric cancer is one of the most common malignancy and the third dominant cause of cancer death worldwide.The......
目的 通过研究血管紧张素Ⅱ(AngⅡ)和血管紧张素(1-7)(Ang(1-7))对博来霉素(BLM)诱导大鼠肺纤维化模型炎症水平的影响,探讨AngⅡ和......
背景和目的 肺癌是目前全世界发病率和死亡率最高的癌症.机体受到外界刺激时,会产生大量活性氧(reactive oxygen species,ROS).NAD......
Aim: In the formation process of atherosclerosis, naringin has showed potential protective effects.However, the mechanis......
Total glucosides of Danggui Buxue Tang inhibits bleomycin-induced pulmonary fibrosis via targeting H
Objective: Danggui Buxue Tang (DBT) is a classical traditional Chinese herbal formula.Previous studies showed that total......
目的：通过观察12周游泳训练和/或表没食子儿茶素没食子酸酯(EGCG)给药对2型糖尿病大鼠心肌NOX4蛋白表达的影响，探讨运动训练和/或EGC......
目的 随着纳米SiO2在人类生产生活中越来越广泛的应用，其诱导的细胞毒性及机制已经成为近年来的研究热点，目前已有大量文献报道纳米S......
Novel hydrogen sulfide releasing derivatives of 3-n-Butylphthallde attenuate ischemic brain damage i
Aim: NBP was employed as the lead compound to obtain a novel class of H2Sreleasing derivatives.We investigated their ant......
Effect of sesamin on pulmonary vascular remodeling in monocrotaline-induced pulmonary hypertension o
Objective: The present study was to investigate the effects of sesamin on pulmonary vascular remodeling in monocrotaline......
心血管疾病是全世界发病率和死亡率最高的疾病，高于肿瘤及其他疾病，占我国居民疾病死亡构成的40%以上。动脉粥样硬化是心血管疾病的......
心肌肥大的特征是心肌细胞体积增大，蛋白质合成增加和肌节组织改变。病理情况下，持续的心肌肥大会伴随间质纤维化、细胞凋亡和收缩功......
β-Arrestin2 deficiency attenuates oxidative stress in mouse hepatic fibrosis through modulation of N
Hepatic fibrosis is a disease characterized by excessive deposition of extracellular matrix(ECM)in the liver.Activation ......
氧化应激是特发性肺纤维化(IPF)的主要致病机制之一,主要通过线粒体和体内酶系统产生的过量活性氧(ROS)引起机体氧化-抗氧化失衡。......
β-Arrestin2 deficiency attenuates oxidative stress in mouse hepatic fibrosis through modulation of N
Hepatic fibrosis is a disease characterized by excessive deposition of extracellular matrix (ECM) in the liver. Activati......
目的:研究雷公藤红素靶向调节NOX4后抑制肿瘤相关成纤维细胞形成的作用和机制.方法:小鼠成纤维细胞NIH3T3和肝癌H22共培养,将细胞......
NOX4-autophagy pathway mediates monocytes-human umbilical vein endothelial cells adhesion enhanced b
Objective: Apelin is the endogenous peptide of the G protein coupled receptor,APJ.Monocytes (MCs) and human umbilica......
目的:探究还原型烟酰胺腺嘌呤二核苷酸磷酸(NADPH)氧化酶4(NOX4)、炎症细胞因子IL-6、hs-CRP水平与房颤的关联性及其对房颤的诊断......
目的:观察苦荞麦总黄酮对软脂酸诱导的人脐静脉内皮(EA.hy926)细胞中还原型尼克酰胺腺嘌呤二核苷酸磷酸氧化酶4(NOX4)表达等指标的......
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[目的]探讨邓老冠心方防治动脉粥样硬化(AS)不稳定斑块发生发展的可能作用机制.[方法]以高脂饲料喂养雄性载脂蛋白E基因敲除(ApoE-......
氧化应激是特发性肺纤维化(IPF)的主要致病机制之一,主要通过线粒体和体内酶系统产生的过量活性氧(ROS)引起机体氧化-抗氧化失衡.......
