Lynch相关论文
目的 结肠直肠癌(CRC)是人类第三大流行癌症之一，是导致癌症相关死亡的第三大常见原因。大多数结肠直肠癌病例为散发性(约75％)，其余25......
Background & Aims: A significant proportion of Lynch syndrome cases are believed to be due to large genomic alterations ......
产后出血是分娩期严重并发症,目前仍居我国孕产妇死亡原因的首位,产后出血的预后随失血量、失血速度及孕妇体质不同而异,若短时间......
最新研究提示,所有结肠癌患者术后都应进行Lynch综合征检查以确定是否患有携带高风险癌症的遗传性综合征。2%～3%的结肠癌患者可能......
随着对Lynch综合征相关的病原学与癌症风险因素研究的进一步深入,Lynch综合征的表型光谱和基因-表型关系已逐步明确。为了评估Lync......
Lynch综合征是由DNA错配修复(MMR)基因突变引起的常染色体显性遗传病,子宫内膜癌是女性Lynch综合征患者最常见的恶性肿瘤。与散发......
Lynch综合征相关性子宫内膜癌(LS-EC)与散发性子宫内膜癌不同,该病是常染色体显性遗传病,是由于DNA错配修复基因(MLH1、MSH2、MSH6......
Reflecting on the Legacy of Kevin Lynch’s Cognitive Approach to City Design through Italian Didactic
In Italy, the writings of Kevin Lynch (1918-1984) have had great influence. However, if The Image of the City (1960, tra......
AIM:To explore the epithelial-mesenchymal transition(EMT)in tissue from patients with Lynch syndrome,and to interpret bi......
Constitutional Mismatch Repair-Deficiency Syndrome Is a Rare Cause of Cancer Even in a Highly Consan
Biallelic germline mutations in the mismatch repair genes, including MLH1, MSH2, MSH6 or PMS2, lead to a recessive const......
Increased and decreased methylation at specific sequences(hypermethylation and hypomethylation, respectively) is charact......
一提到Kevin Lynch，你最先想到的是什么?Bingo，是Dreamweaver!任何一个网页制作者，不论是菜鸟还是开发高手，都离不开它。其实，Dreamweav......
Gastric serrated adenomas are histologically characterized by protruding glands with lateral saw tooth-like indentations......
Lynch syndrome, also known as hereditary nonpolyposiscolorectal cancer, is an autosomal dominant geneticcondition that h......
Hereditary non-polyposis colorectal cancer(HNPCC) was previously synonymous with Lynch syndrome; however,identification ......
Identification of novel Lynch syndrome mutations in Chinese patients with endometriod endometrial ca
Objective:Lynch syndrome(LS)predisposes patients to early onset endometrioid endometrial cancer(EEC).However,little is k......
Colorectal cancer (CRC) incidence and mortality are constantly decreasing, but CRC still remains the third most prevalen......
[Objectives]The research aimed to determine the contents of moisture,ash and extract of wild Paeonia veitchii Lynch prod......
<正>结直肠癌的发病率近几年呈逐年上升趋势,已成为我国的主要恶性肿瘤之一。Lynch综合征(lynch syndrome,LS),又称为遗传性非息肉......
<正>患遗传性非息肉性结肠直肠癌(Lynch综合征)的妇女患子宫内膜癌的终生风险为40％～60％,患卵巢癌的终生风险为10％～12％。对患此类综合征的......
<正>Lynch综合征(lynch syndrome,LS),又称遗传性非息肉状结直肠癌(hereditary non-polyposis color-ectal cancer,HNPCC),属常染......
<正>1病例报告患者,52岁,因月经经期较前延长3~+月,于2017年6月入住我院妇科。3月前开始出现月经经期延长,约10天,经量无明显增多,......
<正>Lynch综合征(LS)是遗传性结直肠癌中最常见(约占5%)的一类常染色体显性遗传病,错配修复基因的种系突变和微卫星不稳定是其区别......
背景和目的大部分结直肠癌属于散发、非遗传性疾病。而Lynch综合征(LS)是最常见的遗传性结直肠癌综合征:每35例结直肠癌中就有一例......
