GENES相关论文
36. Study on p16INK4a and p15INK4b genes of human bronchial epithelial cells malignantly transformed
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Conservation genomics of sibling grouse in boreal forests reveals introgression and adaptive populat
The Chinese Grouse(Tetrastes sewerzowi)and Hazel Grouse(T.bonasia)are sibling species that are well-adapted to harsh hig......
目的:探讨结直肠癌(CRC)患者中循环肿瘤细胞(CTC)、RAS/RAF基因突变及其与临床病理特征之间的相关性。方法:使用扩增阻滞突变系统-......
目的:应用甲基化芯片与生物信息技术，筛选大气污染细颗粒物（PMn 2.5）对人支气管上皮（HBE）细胞的差异甲基化位点及其包含的基因和通......
目的:探讨F框/WD-40域蛋白7（FBXW7）基因突变对非小细胞肺癌（NSCLC）患者免疫治疗预后的影响。方法:（1）选取2019年1月至2021年6月南京医科......
目的:通过对3个n PTPN11基因突变的综合征型耳聋家系的临床表型和基因进行分析，了解其分子生物学病因。n 方法:对2019年1......
目的:探讨n miR-767-3p参与结直肠癌发病的确切机制。n 方法:收集临床原发性结直肠癌患者的结直肠癌组织及其相应癌旁正......
肾母细胞瘤(n WT)n 1基因位于人类染色体11p13，其编码的WT1具有抑制肿瘤生长与激活癌基因转录的双重功能，是一个双向转录因......
目的:筛选支气管哮喘核心差异表达基因并对其进行生物信息学分析。方法:从基因表达数据库（GEO）下载哮喘患者巨噬细胞基因芯片数据GSE......
Activation of the Brain to Postpone Dementia: A Concept Originating from Postmortem Human Brain Stud
Alzheimer\'s disease (AD) is characterized by decreased neuronal activity and atrophy,while hyperactivity of neurons s......
Transcriptome Analysis of Resistance to Meloidogyne incognita in Cucumis Reveals Key Genes Resistant
The southern root-knot nematode, Meloidogyne incognita (Kofoid & White) Chitwood,is a major limiting factor in commercia......
Identification of germline variants that predispose to breast cancer in Chinese Han population by wh
Objective Triple-negative breast cancer(TNBC),the most aggressive subtype of breast cancer,defined by the absence of est......
BACKGROUND:The expression of Src and phospho-Src(p-Src) is closely related to tumor invasion and metastasis. The aim of ......
Prevalence and Clinical Features of Germline Variants in DNA-Repair Pathway Genes in 2353 Unselected
Objective DNA-repair pathway genes play an important role in the etiology and progression of breast cancer.BRCA1/2,along......
Identification of the germline variants that predispose to breast cancer in Chinese Han population b
Objective Background: Triple negative breast cancer(TNBC),the most aggressive subtype of breast cancer,defined by the ab......
The investigation on association of the gene polymorphism with renin-angiotensin system and the neph
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Integrated analysis of differential miRNA and mRNA Expression Profiles in Human Radioresistant and R
To identify miRNAs and genes involved in NPC radioresistance,and explore the underlying mechanisms in the development of......
Protective Immune Responses against Genital Tract Challenge Infection of Dendritic Cells Transfected
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目的:对1个X连锁视网膜劈裂症（XLRS）家系进行基因分析，观察其n RS1基因的突变位点。n 方法:回顾性临床研究。一个4代26人的X......
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The mutation of insulin receptor substrate-1 gene in Chinese patients with non-insulin-dependent dia
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Polymorphisms in the coagulation factor Ⅶ gene and the risk of myocardial infarction in patients und
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GJB2 (Cx26) gene mutations in Chinese patients with congenital sensorineural deafness and a report o
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A genome-wide allelotype study of primary and corresponding recurrent glioblastoma multiforme in one
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Characterization of erythromycin-resistant Streptococcus pneumoniae isolates causing invasive diseas
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乳腺癌易感基因（BRCA）是重要的抑癌基因，其突变与乳腺癌、卵巢癌、胰腺癌、前列腺癌等肿瘤的发生相关。本文综述近年来BRCA基因突变与......
不宁腿综合征（RLS）是一种常见的神经系统疾病，成年人患病率为1%~15%。RLS的病因、发病机制及相关的基因治疗目前尚不完全清楚，研究结果......
目的评价维奈克拉单药或联合CD20单克隆抗体（单抗）治疗复发/难治性慢性淋巴细胞白血病（R/R CLL）的安全性。方法检索PubMed、Embase、中......
目的总结分析儿童非肌性肌球蛋白重链9相关疾病（MYH9-RD）的临床特征及遗传学特点，提高该类疾病的早期诊断。方法通过基因和临床相关指......
目的了解海南省白沙黎族自治县新生儿地中海贫血（简称地贫）检出情况及基因特征，为政府决策部门拟定适宜的地贫防控政策提供数据支持。......
收集海南省2007—2019年参加新生儿疾病筛查的干血斑样本，共1 295 516例，确诊高苯丙氨酸血症43例。其中确诊四氢生物蝶呤缺乏症8例，男......
肌阵挛性癫痫伴破碎红纤维（MERRF）-Leigh叠加综合征是一种罕见的线粒体脑肌病。文中报道1例线粒体基因8344A>G（m. 8344A>G）突变相关的M......
目的对1个并多指(趾)畸形家系中同源盒D13(HOXD13)基因进行分析，探讨该家系中HOXD13基因的突变情况。方法收集2013年8月就诊于福建......
Abstract ［Objectives］ This study was conducted to determine the functions of eight ORF genes of porcine circovirus-like vi......
BACKGROUND Colorectal cancer(CRC)is one of the most malignant gastrointestinal cancers worldwide.The liver is the most i......
Geraniol is an acyclic monoterpenoid compound,which exists widely in aromatic plants.Geraniol has antibacterial and anti......
Genome wide identification and characterization of light-harvesting Chloro a/b binding(LHC)genes rev
Background: Cotton is an important commercial crop for being a valuable source of natural fiber.Its production has under......
BRCA mutation rate and characteristics of prostate tumor in breast and ovarian cancer families:analy
Objective:As prostate cancer(Pr C)shows a BRCA mutation rate as high as 30%,it becomes crucial to find the optimal selec......
Genome-wide association study of micronaire using a natural population of representative upland cott
Background: Micronaire is a comprehensive index reflecting the fineness and maturity of cotton fiber.Micronaire is one o......
