Helicobacter pylori(H.pylori)is known to be a major risk factor for the development of gastric cancer.In recent years,in......

Xuanwei area,in southwestern China,harbors the highest female lung cancer rate in the country (Supplementary Table 1) [1......

Circular RNAs (circRNAs) are noncoding RNAs that form covalently closed loop structures. CircRNAs are dysregulated in ca......

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin tumor in humans. Ultraviolet (UV) radiation is a......

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Objective Cancer is believed to arise from stem cells,but the mechanisms that have evolved by stem cells to limit the ac......

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Bladder cancer is an urinary commom tumor, it is difficult to treat and easy recurrence.The commom treatment drug bladde......

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Background Genetic alterations occurred in etiology and pathogenesis of papillary thyroid cancer (PTC)have been widely i......

Although tumor-associated fetal protein AFP has demonstrated utility as a clinicaltumor marker,the significance of intra......

Many human cancers develop by following many different pathways.These cancers include lung cancer, colon cancer, liver c......

Although tumor-associated fetal protein AFP has demonstrated utility as a clinicaltumor marker,the significance of intra......

DEHP,Di-(2-ethylhexyl)phthalate,the most common plasticizer used in manufactures.It can be leached into a liquid that co......

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Hepatocellular carcinoma(HCC)is the most common type of cancer among primary malignant tumors of the liver and is a cons......

Helicobacter pylori(H.pylori)is an infectious agent influencing as much as 50%of the world’s population.It is the causa......

　　My research group studies human exposure to environmental contaminants and the potential health effects arising from......

　　Objective: To study the mechanism on malignant transformation of human bronchial epithelial cell line BEP2D induced ......

Lung cancer is a worldwide leading cause of cancer death.But carcinogenic mechanism of lung cancer still need to be eluc......

Heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1,an RNA binding protein,is overexpressed in many tumor cells and it......

Objective:Hepatocyte nuclear factor 4α (HNF4A) has been demonstrated to be an oncogene in gastric cancer (GC). However,......

Multiple myeloma (MM) is a uniformly fatal disease characterized by a clonal proliferation of neoplastic plasma cells in......

BACKGROUND: TMS1/ASC is a bipartite protein comprising two protein-protein interactive domains: pyrin (PYD) and caspase ......

Objective: This study was designed to investigate promoter methylation status and protein expression of p14ARF gene in n......

Objective To examine the differentially expressed invasion-related genes in two anchorage-independent uterine cervical c......

AIM: To investigate whether krUppel-like factor 6 (KLF6) plays an important role in the development and/or progression o......

AIM: To study the differential gene expression profiles of target cells in primary gastric cancer and its metastatic lym......

AIM:To investigate the interrelationship of Epstein-Barrvirus(EBV)and EBV-encoded proteins with Helicobacterpylori(H py......

AIM: To investigate the distribution of beta-catenin in nuclei or membrane/cytoplasm of gastric carcinoma cells, the rel......

In 1979, the mechanism of chemical carcinogenesis, a challenging and difficult scientific problem pending for a number o......

The risk of hepatocellular carcinoma(HCC) development increases as hepatitis virus C(HCV)-related liver diseases progres......

Objective: To investigate the correlation between 17-beta-hydroxysteroid dehydrogenase type1(17β-HSD-1) gene polymorphi......

It is evidenced by the filter elution method that two carcinogenic aromatic hydrocarbons, benzo[a]pyrene and dibenzo[a,h......

Ab initio calculation is carried out to study the different supposed mechanisms of DNA base alkylation by [β-sulphate-n......

BACKGROUND:Recent studies have confirmed that the expression of Ezrin,hepatocyte growth factor(HGF)and its receptor(C-me......

迄今已有不少文献报道,癌患者常常有原发性的或继发性的硒缺乏,并认为它可能与致癌作用(carcinogenesis)和肿瘤行为有关。另一方......

Over the past years,it has been found that the epigenetic silence of tumor suppressor genes induced by overexpression of......

Microbial polyhydroxyalkanoates(PHAs) are a family of biopolyesters produced by many wild type and engineered bacteria.P......

An increasing body of evidence suggests that apoptosis of structural cells in the lung might be an important upstream ev......

Objective:The aim of our study was to investigate the expression of guanine nucleotide exchange factor Dock180 in ovaria......

Gastric cancer is a leading cause of cancer-related deaths. However, the mechanisms underlying gastric carcinogenesis re......

Gastric cancer(GC) is one of the most common carcino-ma and the second leading cause of cancer-related deaths worldwide.......

Objective: The aim of the study was to investigate the correlation of zinc-finger protein 217(ZNF217) gene expression wi......